Search Results - "Mayhew, Gregory"

Lung Adenocarcinoma and Squamous Cell Carcinoma Gene Expression Subtypes Demonstrate Significant Differences in Tumor Immune Landscape by Faruki, Hawazin, Mayhew, Gregory M, Serody, Jonathan S, Hayes, D Neil, Perou, Charles M, Lai-Goldman, Myla

“…Molecular subtyping of lung adenocarcinoma (AD) and lung squamous cell carcinoma (SCC) reveal biologically diverse tumors that vary in their genomic and…”
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Fibroblast growth factor receptor 3 alterations and response to immune checkpoint inhibition in metastatic urothelial cancer: a real world experience by Rose, Tracy L., Weir, William H., Mayhew, Gregory M., Shibata, Yoichiro, Eulitt, Patrick, Uronis, Joshua M., Zhou, Mi, Nielsen, Matthew, Smith, Angela B., Woods, Michael, Hayward, Michele C., Salazar, Ashley H., Milowsky, Matthew I., Wobker, Sara E., McGinty, Katrina, Millburn, Michael V., Eisner, Joel R., Kim, William Y.

“…Background FGFR3-altered urothelial cancer (UC) correlates with a non-T cell-inflamed phenotype and has therefore been postulated to be less responsive to…”
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Pesticide exposure and risk of Parkinson's disease: a family-based case-control study by Hancock, Dana B, Martin, Eden R, Mayhew, Gregory M, Stajich, Jeffrey M, Jewett, Rita, Stacy, Mark A, Scott, Burton L, Vance, Jeffery M, Scott, William K

“…Pesticides and correlated lifestyle factors (e.g., exposure to well-water and farming) are repeatedly reported risk factors for Parkinson's disease (PD), but…”
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Mesenchymal gene expression subtyping analysis for early-stage human papillomavirus-negative head and neck squamous cell carcinoma reveals prognostic and predictive applications by Mayhew, Gregory M., Uronis, Joshua M., Hayes, David Neil, Zevallos, Jose P.

“…Patients with oral cavity squamous cell carcinoma (OCSCC) are predominantly human papillomavirus (HPV)(−), and treatment typically involves surgical resection…”
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Association of Antifolate Response Signature Status and Clinical Activity of Pemetrexed-Platinum Chemotherapy in Non-Small Cell Lung Cancer: The Piedmont Study by Eisner, Joel R, Mayhew, Gregory M, Davison, James M, Beebe, Kirk D, Shibata, Yoichiro, Guo, Yuelong, Farhangfar, Carol, Farhangfar, Farhang, Uronis, Joshua M, Conroy, Jeffrey M, Milburn, Michael V, Hayes, David Neil, Mileham, Kathryn F

“…The Piedmont study is a prospectively designed retrospective evaluation of a new 48-gene antifolate response signature (AF-PRS) in patients with locally…”
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Genome-wide association and linkage identify modifier loci of lung disease severity in cystic fibrosis at 11p13 and 20q13.2 by Wright, Fred A, Strug, Lisa J, Doshi, Vishal K, Commander, Clayton W, Blackman, Scott M, Sun, Lei, Berthiaume, Yves, Cutler, David, Cojocaru, Andreea, Collaco, J Michael, Corey, Mary, Dorfman, Ruslan, Goddard, Katrina, Green, Deanna, Kent, Jack W, Lange, Ethan M, Lee, Seunggeun, Li, Weili, Luo, Jingchun, Mayhew, Gregory M, Naughton, Kathleen M, Pace, Rhonda G, Paré, Peter, Rommens, Johanna M, Sandford, Andrew, Stonebraker, Jaclyn R, Sun, Wei, Taylor, Chelsea, Vanscoy, Lori L, Zou, Fei, Blangero, John, Zielenski, Julian, O'Neal, Wanda K, Drumm, Mitchell L, Durie, Peter R, Knowles, Michael R, Cutting, Garry R

“…Garry Cutting and colleagues report a genome-wide association and linkage study for loci that affect lung disease severity in cystic fibrosis. They identify…”
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Correction to: Fibroblast growth factor receptor 3 alterations and response to immune checkpoint inhibition in metastatic urothelial cancer: a real world experience by Rose, Tracy L., Weir, William H., Mayhew, Gregory M., Shibata, Yoichiro, Eulitt, Patrick, Uronis, Joshua M., Zhou, Mi, Nielsen, Matthew, Smith, Angela B., Woods, Michael, Hayward, Michele C., Salazar, Ashley H., Milowsky, Matthew I., Wobker, Sara E., McGinty, Katrina, Millburn, Michael V., Eisner, Joel R., Kim, William Y.

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Validation of the Lung Subtyping Panel in Multiple Fresh-Frozen and Formalin-Fixed, Paraffin-Embedded Lung Tumor Gene Expression Data Sets by Faruki, Hawazin, Mayhew, Gregory M, Fan, Cheng, Wilkerson, Matthew D, Parker, Scott, Kam-Morgan, Lauren, Eisenberg, Marcia, Horten, Bruce, Hayes, D Neil, Perou, Charles M, Lai-Goldman, Myla

“…Context .- A histologic classification of lung cancer subtypes is essential in guiding therapeutic management. Objective .- To complement morphology-based…”
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Distinct Predictive Immunogenomic Profiles of Response to Immune Checkpoint Inhibitors and IL2: A Real-world Evidence Study of Patients with Advanced Renal Cancer by Eisner, Joel R, Beebe, Kirk D, Mayhew, Gregory M, Shibata, Yoichiro, Guo, Yuelong, Farhangfar, Carol, Farhangfar, Farhang, Uronis, Joshua M, Mooney, Jill, Milburn, Michael V, Foureau, David, White, Richard L, Amin, Asim, Milla, Marcos E

“…Recombinant human high-dose IL2 (HD-IL2; aldesleukin) was one of the first approved immune-oncology agents based upon clinical activity in renal cell carcinoma…”
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Family-based case-control study of MAOA and MAOB polymorphisms in Parkinson disease by Kang, Sun J., Scott, William K., Li, Yi-Ju, Hauser, Michael A., van der Walt, Joelle M., Fujiwara, Kenichiro, Mayhew, Gregory M., West, Sandra G., Vance, Jeffery M., Martin, Eden R.

“…Monoamine oxidase (MAO) is an enzyme regulating metabolism of neurotransmitters such as dopamine. Two distinct forms of enzyme, encoded by genes MAOA and MAOB…”
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Dynamic message prioritization in tactical wireless MANET by Mayhew, Gregory L

“…Normal design practice is to decouple the design of applications using a network from the design of the network itself. Designers optimize network performance…”
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Rooted tree graphs and de Bruijn graphs by Mayhew, Gregory L

“…The de Bruijn graph G n illustrates all possible transitions in an n-stage binary shift register. Most feedback functions for an n-stage shift register…”
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Convolutional Codes Using Nonlinear Generators for Rate One-half and Memory Order Four by Mayhew, G.L.

“…Performance of a convolutional code depends on the decoding algorithm and that code's distance properties. Performance bounds suggest constructing codes with…”
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Development of a novel RNA-based immune checkpoint inhibitor response signature (ICI-PRS) that avoids standard-of-care (SOC) prognostic signal for use in patients with urothelial cancer (UC) by Shepherd, Jonathan, Mayhew, Gregory, Guo, John, Beebe, Kirk, Eisner, Joel Robert, Milburn, Michael Vance

“…549 Background: Immune checkpoint inhibition (ICI) shows great promise, including approval of pembrolizumab, nivolumab and avelumab in urothelial cancer (UC)…”
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Group property of the P4, K4, and NR16 error correction codes by Mayhew, Gregory

“…Error correction codes are vital for data accuracy on the communication links in NASA inter-planetary missions. Preparata4, Kerdock4, and Nordstrom-Robinson16…”
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Extreme weight classes of de Bruijn sequences by Mayhew, Gregory L.

“…Order n de Bruijn sequences are the period 2 n binary sequences produced by an n stage feedback shift register. Properties of the number of sequences in the…”
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Development of a novel RNA-based fibroblast growth factor receptor response signature (FGFR-PRS) for use in patients with urothelial cancer (UC) by Pappan, Kirk L., Mayhew, Gregory, Davison, James M., Shibata, Yoichiro, Eisner, Joel Robert, Beebe, Kirk, Milburn, Michael Vance

“…548 Background: Interest in FGFR-targeted (FGFRi) therapies for UC or pan-tumor use is growing (ongoing clinical studies include erdafitinib (NCT05316155;…”
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Further results on de Bruijn weight classes by L. Mayhew, Gregory

“…Order n de Bruijn sequences are the period 2 n binary sequences produced by an n stage feedback shift register. Additional information is given on the weight…”
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Characterization of FGFR Alterations and Activation in Patients with High-Risk Non–Muscle-Invasive Bladder Cancer by Eisner, Joel R., de Jong, Florus C., Shibata, Yoichiro, Mayhew, Gregory M., Davison, James M., Carcione, Jenna, Pappan, Kirk L., Thomas, Shibu, Triantos, Spyros, Santiago-Walker, Ademi, Baig, Mahadi, Milburn, Michael V., Beebe, Kirk D., Zuiverloon, Tahlita C.M.

“…Abstract Purpose: The Genomic Analysis of High-Risk Non–Muscle-Invasive Bladder Cancer (GARNER) study investigated FGFR alteration (ALT) frequency and the…”
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Molecular characterization of advanced muscle invasive bladder cancer (MIBC): Comparison of low-input targeted RNA sequencing (RNAseq) strategies by Shibata, Yoichiro, Uronis, Joshua M., Conroy, Jeffrey M., Glenn, Sean, Guo, John, Mayhew, Gregory, Eisner, Joel Robert, Milburn, Michael Vance

“…Abstract only 564 Background: 5-year survival for advanced MIBC is poor (~5%), but newer targeted agents (e.g., PD-1/PD-L1 or FGFR) have improved survival over…”
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