Search Results - "Mayeux, Jessica M"
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Silicosis and Silica-Induced Autoimmunity in the Diversity Outbred Mouse
Published in Frontiers in immunology (26-04-2018)“…Epidemiological studies have confidently linked occupational crystalline silica exposure to autoimmunity, but pathogenic mechanisms and role of genetic…”
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Facial shape and allometry quantitative trait locus intervals in the Diversity Outbred mouse are enriched for known skeletal and facial development genes
Published in PloS one (05-06-2020)“…The biology of how faces are built and come to differ from one another is complex. Discovering normal variants that contribute to differences in facial…”
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Developmental constraint through negative pleiotropy in the zygomatic arch
Published in EvoDevo (27-01-2018)“…Previous analysis suggested that the relative contribution of individual bones to regional skull lengths differ between inbred mouse strains. If the negative…”
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Development of experimental silicosis in inbred and outbred mice depends on instillation volume
Published in Scientific reports (02-10-2019)“…There is considerable variation in methods to induce experimental silicosis with the effects of dose and route of exposure being well documented. However, to…”
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Mechanisms of Environment-Induced Autoimmunity
Published in Annual review of pharmacology and toxicology (06-01-2021)“…Although numerous environmental exposures have been suggested as triggers for preclinical autoimmunity, only a few have been confidently linked to autoimmune…”
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Silica exposure and chronic virus infection synergistically promote lupus-like systemic autoimmunity in mice with low genetic predisposition
Published in Clinical immunology (Orlando, Fla.) (01-08-2019)“…Considerable evidence indicates that autoimmune disease expression depends on both genetic and environmental factors. Among potential environmental triggers,…”
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Ebola-Specific CD8+ and CD4+ T-Cell Responses in Sierra Leonean Ebola Virus Survivors With or Without Post-Ebola Sequelae
Published in The Journal of infectious diseases (01-10-2020)“…Ebola virus (EBOV) disease has killed thousands of West and Central Africans over the past several decades. Many who survive the acute disease later experience…”
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Induction of Systemic Autoimmunity by a Xenobiotic Requires Endosomal TLR Trafficking and Signaling from the Late Endosome and Endolysosome but Not Type I IFN
Published in The Journal of immunology (1950) (01-12-2017)“…Type I IFN and nucleic acid-sensing TLRs are both strongly implicated in the pathogenesis of lupus, with most patients expressing IFN-induced genes in…”
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IL‐21 promotes the production of anti‐DNA IgG but is dispensable for kidney damage in lyn−/− mice
Published in European journal of immunology (01-02-2013)“…The autoimmune disease systemic lupus erythematosus is characterized by loss of tolerance to nuclear Ags and a heightened inflammatory environment, which…”
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10
Mechanisms of Environmental-Induced Autoimmunity
Published in Annual review of pharmacology and toxicology (28-08-2020)“…Although numerous environmental exposures have been suggested as triggers for pre-clinical autoimmunity, only a few have been confidently linked to autoimmune…”
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11
IL-21 promotes the production of anti-DNA IgG but is dispensable for kidney damage in lyn super(-/-) mice
Published in European journal of immunology (01-02-2013)“…The autoimmune disease systemic lupus erythematosus is characterized by loss of tolerance to nuclear Ags and a heightened inflammatory environment, which…”
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