Search Results - "Mayer, P R"

Phase I trial of oral MAC-321 in subjects with advanced malignant solid tumors by LOCKHART, A. C, BUKOWSKI, R, ROTHENBERG, M. L, WANG, K. K, COOPER, W, GROVER, J, APPLEMAN, L, MAYER, P. R, SHAPIRO, M, ZHU, A. X

“…MAC-321 is a novel taxane that has demonstrated exceptional activity in human xenograft models when administered intravenously and orally. Preclinical studies…”
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Pharmacodynamic Modeling of Pantoprazole's Irreversible Effect on Gastric Acid Secretion in Humans and Rats by Ferron, Geraldine M., McKeand, William, Mayer, Philip R.

“…The relationship between the pharmacokinetics of pantoprazole, an irreversible proton pump inhibitor, and its effect on gastric acid secretion was evaluated in…”
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Pharmacokinetics of promethazine hydrochloride after administration of rectal suppositories and oral syrup to healthy subjects by Strenkoski-Nix, LC, Ermer, J, DeCleene, S, Cevallos, W, Mayer, PR

“…The pharmacokinetics of promethazine hydrochloride after administration of rectal suppositories at three dosage strengths and oral syrup were studied. The…”
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Differential Amplifier With Current-Mirror Load: Influence of Current Gain, Early Voltage, and Supply Voltage on the DC Output Voltage by Paulik, G. F., Mayer, R. P.

“…A differential amplifier composed of an emitter-coupled pair is useful as an example in lecture presentations and laboratory experiments in electronic circuit…”
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Lack of Pharmacokinetic Interaction between Oral Pantoprazole and Cisapride in Healthy Adults by Ferron, Geraldine M., Paul, Jeffrey C., Fruncillo, Richard J., Martin, Patrick T., Yacoub, Lena, Mayer, Philip R.

“…Pantoprazole, an irreversible proton pump inhibitor, may be administered with cisapride, a prokinetic agent. As increased cisapride concentrations may result…”
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Absorption, metabolism, and other factors that influence drug exposure in toxicology studies by Mayer, P R

“…Drug exposure in toxicology studies is dependent on input from the drug delivery system and elimination of the drug once absorbed. Although seemingly…”
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Capillary zone electrophoresis compared with agarose gel and immunofixation electrophoresis by Smalley, D L, Mayer, R P, Bugg, M F

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Excretion of fluorescein into breast milk by Mattern, J, Mayer, P R

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Pulmonary inversion of 2-arylpropionic acids: influence of protein binding by Hall, S D, Hassanzadeh-Khayyat, M, Knadler, M P, Mayer, P R

“…The possible contribution of pulmonary metabolism to the putative first-pass metabolism of 2-arylpropionic acid nonsteroidal antiinflammatory drugs has not…”
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Relationship between rat renal accumulation of gentamicin, tobramycin, and netilmicin and their nephrotoxicities by BRIER, M. E, MAYER, P. R, BRIER, R. A, VISSCHER, D, LUFT, F. C, ARONOFF, G. R

“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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A comparison of phenytoin dosing methods in private practice seizure patients by Welty, T E, Robinson, F C, Mayer, P R

“…In an attempt to evaluate the accuracy of phenytoin (PHT) pharmacokinetic dosage adjustments in a private practice setting, three single dose-concentration…”
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Effect of acute renal failure on insulin disposition in the isolated perfused rat kidney by Brier, M E, Aronoff, G R, Mayer, P R

“…The renal disposition of insulin in acute renal failure has not been evaluated. We used the isolated perfused rat kidney to test the hypothesis that acute…”
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Saturable tissue binding and imirestat pharmacokinetics in rats by CHIEN, J. Y, BANFIELD, C. R, BRAZZELL, R. K, MAYER, P. R, SLATTERY, J. T

“…To investigate the hypothesis that the pharmacokinetics of imirestat, an aldose reductase inhibitor, are influenced by saturable binding to tissues, three…”
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Dose-dependent pharmacokinetics of the aldose reductase inhibitor imirestat in man by BRAZZELL, R. K, MAYER, P. R, DOBBS, R, MCNAMARA, P. J, RENLI TENG, SLATTERY, J. T

“…The pharmacokinetics of imirestat were studied in healthy volunteers following single and multiple oral doses. After single doses of 20 to 50 mg, imirestat…”
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Determination of AL01576 concentration in rat lenses and plasma by bioassay for aldose reductase activity measurements by Hockwin, O, Müller, P, Krolczyk, J, McCue, B A, Mayer, P R

“…Investigations on the disposition of the highly effective aldose reductase inhibitor AL01576 were carried out in pigmented rats after oral dosing and topical…”
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Pharmacokinetic analysis of potassium cyanate in mice using whole blood and expired air by Johnson, J D, Mayer, P R, Isom, G E

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Comparison of the pharmacokinetics and pharmacodynamics of the aldose reductase inhibitors, AL03152 (RS), AL03802 (R), and AL03803 (S) by YOUNG HAN PARK, MAYER, P. R, BARKER, R, DUPRIEST, M, GRIFFIN, B. W, WILLIAMS, G. W, YORK, B. M, SLATTERY, J. T

“…The pharmacokinetics of AL03152 (RS) and its enantiomers, AL03802 (R) and AL03803 (S), were studied in the Sprague-Dawley rat following intravenous bolus…”
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The effect of carbon monoxide on aminopyrine metabolism in the isolated perfused rabbit lung by Trela, B A, Carlson, G P, Mayer, P R

“…Carbon monoxide (CO) is a ubiquitous environmental pollutant widely recognized for its ability to inhibit cytochrome P450-mediated metabolism of xenobiotics in…”
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Conversion of p-tyrosine to p-tyramine in the isolated perfused rat kidney: modulation by perfusate concentrations of p-tyrosine by Brier, M E, Bowsher, R R, Mayer, P R, Henry, D P

“…We used the isolated perfused rat kidney to evaluate the role of renal decarboxylation of p-tyrosine as the source of urinary p-tyramine. Kidneys were perfused…”
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Topical and systemic absorption of sodium pyrithione following topical application to the nails of the rhesus monkey by Mayer, P R, Couch, R C, Erickson, M K, Wooldridge, C B, Brazzell, R K

“…A study was performed to investigate the local penetration into the nail, the systemic absorption into the rest of the body, and the routes of excretion of…”
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