Search Results - "Mayer, Karoline"
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Lipid Peroxidation Plays an Important Role in Chemotherapeutic Effects of Temozolomide and the Development of Therapy Resistance in Human Glioblastoma
Published in Translational oncology (01-03-2020)“…BACKGROUND: Glioblastoma (GBM) is the most malignant primary brain tumor. Relapse occurs regularly, and the clinical behavior seems to be due to a…”
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Deciphering the immunological interactions: targeting preeclampsia with Hydroxychloroquine's biological mechanisms
Published in Frontiers in pharmacology (05-02-2024)“…Preeclampsia (PE) is a complex pregnancy-related disorder characterized by hypertension, followed by organ dysfunction and uteroplacental abnormalities. It…”
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Preeclampsia and the Antiphospholipid Syndrome
Published in Biomedicines (01-08-2023)“…Antiphospholipid syndrome (APS) is characterized by venous or arterial thrombosis and/or adverse pregnancy outcome in the presence of persistent laboratory…”
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The Impact of Hydroxychloroquine on Primary Feto-Placental Endothelial Cells from Healthy and Early-Onset Preeclamptic Placentas
Published in International journal of molecular sciences (30-06-2023)“…Hydroxychloroquine (HCQ), an anti-malarial drug, is suggested as a promising candidate for the treatment of pregnancy-related disorders associated with…”
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Obstetrical outcome and treatments in seronegative primary APS: data from European retrospective study
Published in Rheumatic & musculoskeletal diseases open (01-08-2020)“…ObjectiveTo compare characteristics, pregnancies and treatments during pregnancies of seronegative and seropositive antiphospholipid syndrome (APS), to analyse…”
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Response to Plasmapheresis Measured by Angiogenic Factors in a Woman with Antiphospholipid Syndrome in Pregnancy
Published in Case reports in obstetrics and gynecology (01-01-2015)“…An imbalance of angiogenic and antiangiogenic placental factors such as endoglin and soluble fms-like tyrosine kinase 1 has been implicated in the…”
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Inherited thrombophilia in women with poor aPL-related obstetric history: prevalence and outcomes. Survey of 208 cases from the European Registry on Obstetric Antiphospholipid Syndrome cohort
Published in American journal of reproductive immunology (1989) (01-08-2016)“…Aim To analyse the prevalence and effects of inherited thrombophilic disorders (ITD) on maternal–foetal outcomes in cases of antiphospholipid antibody related…”
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Multiscale quantification of morphological heterogeneity with creation of a predictor of longer survival in glioblastoma
Published in International journal of cancer (01-11-2023)“…Intratumor heterogeneity is a main cause of the dismal prognosis of glioblastoma (GBM). Yet, there remains a lack of a uniform assessment of the degree of…”
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Immunohistochemically Characterized Intratumoral Heterogeneity Is a Prognostic Marker in Human Glioblastoma
Published in Cancers (13-10-2020)“…Tumor heterogeneity is considered to be a hallmark of glioblastoma (GBM). Only more recently, it has become apparent that GBM is not only heterogeneous between…”
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The 2023 ACR / EULAR Antiphospholipid Syndrome Classification Criteria
Published in Arthritis & rheumatology (Hoboken, N.J.) (01-10-2023)“…ObjectiveTo develop new antiphospholipid syndrome (APS) classification criteria with high specificity for use in observational studies and trials, jointly…”
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Comparison of mean platelet volume (MPV) and sFlt-1/PlGF ratio as predictive markers for preeclampsia
Published in The journal of maternal-fetal & neonatal medicine (03-05-2021)“…Preeclampsia is characterised by an increased platelet consumption with consecutive reduction of overall platelet count and a consecutive rise in mean platelet…”
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Steroid Profiles and Precursor-to-Product Ratios Are Altered in Pregnant Women with Preeclampsia
Published in International journal of molecular sciences (26-11-2024)“…Steroid hormone imbalance is associated with the pathogenesis of preeclampsia. However, affected enzymes of steroid metabolism and gene and protein expression…”
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Pregnancy Outcome in Women with Obstetric and Thrombotic Antiphospholipid Syndrome—A Retrospective Analysis and a Review of Additional Treatment in Pregnancy
Published in Clinical reviews in allergy & immunology (01-08-2017)“…Antiphospholipid syndrome (APS) is associated with pregnancy complications such as recurrent early fetal loss (RFL), fetal death, preeclampsia (PE), and…”
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Comparative study of obstetric antiphospholipid syndrome (OAPS) and non-criteria obstetric APS (NC-OAPS): report of 1640 cases from the EUROAPS registry
Published in Rheumatology (Oxford, England) (01-06-2020)“…Abstract Objectives To compare clinical features, laboratory data and fetal-maternal outcomes between 1000 women with obstetric APS (OAPS) and 640 with…”
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Preeclampsia before fetal viability in women with primary antiphospholipid syndrome- materno-fetal outcomes in a series of 7 cases
Published in Journal of reproductive immunology (01-04-2020)“…•Women with APS are at increased risk for the development of preeclampsia, sometimes before fetal viability.•Preeclampsia is associated with serious and…”
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Changes of platelet count throughout pregnancy in women with antiphospholipid syndrome
Published in Journal of reproductive immunology (01-11-2019)“…•Platelet count was significantly lower in women with APS to women who developed preeclampsia and to healthy pregnant women.•Platelet count has a high…”
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Angiogenic factors in pregnancies of women with antiphospholipid syndrome and systemic lupus erythematosus
Published in Journal of reproductive immunology (01-06-2018)“…•The antiphospholipid syndrome and systemic lupus erythematosus have an increased risk of developing especially preeclampsia in pregnancy.•Measurement of…”
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The European Registry on Obstetric Antiphospholipid Syndrome (EUROAPS): A survey of 1000 consecutive cases
Published in Autoimmunity reviews (01-04-2019)“…To analyse the clinical features, laboratory data and foetal-maternal outcomes, and follow them up on a cohort of 1000 women with obstetric antiphospholipid…”
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