Search Results - "Mayer, Emeran A."

The Gut-Brain Axis by Mayer, Emeran A, Nance, Karina, Chen, Shelley

“…Preclinical evidence has firmly established bidirectional interactions among the brain, the gut, and the gut microbiome. Candidate signaling molecules and at…”
Get full text

The Microbiota-Gut-Brain Axis: From Motility to Mood by Margolis, Kara G., Cryan, John F., Mayer, Emeran A.

“…The gut-brain axis plays an important role in maintaining homeostasis. Many intrinsic and extrinsic factors influence signaling along this axis, modulating the…”
Get full text

Brain–gut–microbiome interactions in obesity and food addiction by Gupta, Arpana, Osadchiy, Vadim, Mayer, Emeran A.

“…Normal eating behaviour is coordinated by the tightly regulated balance between intestinal and extra-intestinal homeostatic and hedonic mechanisms. By…”
Get full text

The Gut–Brain Axis and the Microbiome: Mechanisms and Clinical Implications by Osadchiy, Vadim, Martin, Clair R., Mayer, Emeran A.

“…Based largely on results from preclinical studies, the concept of a brain gut microbiome axis has been established, mediating bidirectional communication…”
Get full text

Altered brain-gut axis in autism: Comorbidity or causative mechanisms? by Mayer, Emeran A., Padua, David, Tillisch, Kirsten

“…The concept that alterated communications between the gut microbiome and the brain may play an important role in human brain disorders has recently received…”
Get full text

Brain–Gut Microbiome Interactions and Functional Bowel Disorders by Mayer, Emeran A, Savidge, Tor, Shulman, Robert J

“…Alterations in the bidirectional interactions between the intestine and the nervous system have important roles in the pathogenesis of irritable bowel syndrome…”
Get full text

Gut microbes and the brain: paradigm shift in neuroscience by Mayer, Emeran A, Knight, Rob, Mazmanian, Sarkis K, Cryan, John F, Tillisch, Kirsten

“…The discovery of the size and complexity of the human microbiome has resulted in an ongoing reevaluation of many concepts of health and disease, including…”
Get full text

The brain-gut axis in abdominal pain syndromes by Mayer, Emeran A, Tillisch, Kirsten

“…The importance of bidirectional brain-gut interactions in gastrointestinal (GI) illness is increasingly recognized, most prominently in the area of functional…”
Get full text

Role of brain imaging in disorders of brain-gut interaction: a Rome Working Team Report by Mayer, Emeran A, Labus, Jennifer, Aziz, Qasim, Tracey, Irene, Kilpatrick, Lisa, Elsenbruch, Sigrid, Schweinhardt, Petra, Van Oudenhove, Lukas, Borsook, David

“…Imaging of the living human brain is a powerful tool to probe the interactions between brain, gut and microbiome in health and in disorders of brain-gut…”
Get more information

Considering Sex as a Biological Variable in Basic and Clinical Studies: An Endocrine Society Scientific Statement by Bhargava, Aditi, Arnold, Arthur P, Bangasser, Debra A, Denton, Kate M, Gupta, Arpana, Hilliard Krause, Lucinda M, Mayer, Emeran A, McCarthy, Margaret, Miller, Walter L, Raznahan, Armin, Verma, Ragini

“…Abstract In May 2014, the National Institutes of Health (NIH) stated its intent to “require applicants to consider sex as a biological variable (SABV) in the…”
Get full text

Quantitative Meta-analysis Identifies Brain Regions Activated During Rectal Distension in Irritable Bowel Syndrome by Tillisch, Kirsten, Mayer, Emeran A, Labus, Jennifer S

“…Background and Aims The responsiveness of the central nervous system is altered in patients with irritable bowel syndrome (IBS). However, because of variations…”
Get full text

An update on the use and investigation of probiotics in health and disease by Sanders, Mary Ellen, Guarner, Francisco, Guerrant, Richard, Holt, Peter R, Quigley, Eamonn M M, Sartor, R Balfour, Sherman, Philip M, Mayer, Emeran A

“…Probiotics are derived from traditional fermented foods, from beneficial commensals or from the environment. They act through diverse mechanisms affecting the…”
Get more information

The visceral sensitivity index: A novel tool for measuring GI‐symptom‐specific anxiety in inflammatory bowel disease by Trieschmann, Kimberly, Chang, Lin, Park, Sarah, Naliboff, Bruce, Joshi, Swapna, Labus, Jennifer S., Sauk, Jenny S., Limketkai, Berkeley N., Mayer, Emeran A.

“…Background Irritable bowel syndrome (IBS) and inflammatory bowel disease (IBD) are chronic gastrointestinal (GI) disorders. GI symptom‐specific anxiety (GSA)…”
Get full text

Brain Structure and Response to Emotional Stimuli as Related to Gut Microbial Profiles in Healthy Women by Tillisch, Kirsten, Mayer, Emeran A, Gupta, Arpana, Gill, Zafar, Brazeilles, Rémi, Le Nevé, Boris, van Hylckama Vlieg, Johan E T, Guyonnet, Denis, Derrien, Muriel, Labus, Jennifer S

“…Brain-gut-microbiota interactions may play an important role in human health and behavior. Although rodent models have demonstrated effects of the gut…”
Get full text

Brain-Gut-Microbiome Interactions and Intermittent Fasting in Obesity by Frank, Juliette, Gupta, Arpana, Osadchiy, Vadim, Mayer, Emeran A

“…The obesity epidemic and its metabolic consequences are a major public health problem both in the USA and globally. While the underlying causes are…”
Get full text

Association Between Early Adverse Life Events and Irritable Bowel Syndrome by Bradford, Kara, Shih, Wendy, Videlock, Elizabeth J, Presson, Angela P, Naliboff, Bruce D, Mayer, Emeran A, Chang, Lin

“…Background & Aims Although childhood and adult abuse are more prevalent among patients with irritable bowel syndrome (IBS) than healthy individuals (controls),…”
Get full text

Expression of the Bitter Taste Receptor, T2R38, in Enteroendocrine Cells of the Colonic Mucosa of Overweight/Obese vs. Lean Subjects by Latorre, Rocco, Huynh, Jennifer, Mazzoni, Maurizio, Gupta, Arpana, Bonora, Elena, Clavenzani, Paolo, Chang, Lin, Mayer, Emeran A, De Giorgio, Roberto, Sternini, Catia

“…Bitter taste receptors (T2Rs) are expressed in the mammalian gastrointestinal mucosa. In the mouse colon, T2R138 is localized to enteroendocrine cells and is…”
Get full text

Differences in gut microbial composition correlate with regional brain volumes in irritable bowel syndrome by Labus, Jennifer S, Hollister, Emily B, Jacobs, Jonathan, Kirbach, Kyleigh, Oezguen, Numan, Gupta, Arpana, Acosta, Jonathan, Luna, Ruth Ann, Aagaard, Kjersti, Versalovic, James, Savidge, Tor, Hsiao, Elaine, Tillisch, Kirsten, Mayer, Emeran A

“…Preclinical and clinical evidence supports the concept of bidirectional brain-gut microbiome interactions. We aimed to determine if subgroups of irritable…”
Get full text

Psychometric properties of the early trauma inventory-self report by BREMNER, J. Douglas, BOLUS, Roger, MAYER, Emeran A

“…Childhood trauma is an important public health problem, but there are limitations in our ability to measure childhood abuse. The purpose of this study was to…”
Get full text

Correlation of tryptophan metabolites with connectivity of extended central reward network in healthy subjects by Osadchiy, Vadim, Labus, Jennifer S, Gupta, Arpana, Jacobs, Jonathan, Ashe-McNalley, Cody, Hsiao, Elaine Y, Mayer, Emeran A

“…A growing body of preclinical and clinical literature suggests that brain-gut-microbiota interactions play an important role in human health and disease,…”
Get full text