Search Results - "Mayer, Catherine A."

A critical postnatal period of heightened vulnerability to lipopolysaccharide by Rourke, Kyle S, Mayer, Catherine A, MacFarlane, Peter M

“…Highlights • Vulnerability of respiratory neural control to LPS during a window of postnatal development. • An aberrant increase in brainstem cytokine mRNA…”
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Prenatal Maternal Lipopolysaccharide and Mild Newborn Hyperoxia Increase Intrapulmonary Airway but Not Vessel Reactivity in a Mouse Model by Kuper-Sassé, Margaret E, MacFarlane, Peter M, Mayer, Catherine A, Martin, Richard J, Prakash, Y S, Pabelick, Christina M, Raffay, Thomas M

“…Maternal infection is a risk for preterm delivery. Preterm newborns often require supplemental oxygen to treat neonatal respiratory distress. Newborn hyperoxia…”
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Cardiorespiratory anomalies and increased brainstem microglia in a rat model of neonatal opioid withdrawal syndrome by Osborne, Allison, Mayer, Catherine A., Hoffman, Adriana, Cali, Valbona, Hyzny, Rachel, Lewis, Stephen J., MacFarlane, Peter M.

“…•In a rat model of NOWS, offspring exhibit tachypnea and tachycardia.•NOWS rats also exhibit an attenuated HVR and HCVR.•Cardiorespiratory features of NOWS are…”
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CPAP protects against hyperoxia-induced increase in airway reactivity in neonatal mice by MacFarlane, Peter M., Mayer, Catherine A., Jafri, Anjum, Pabelick, Christina M., Prakash, Y. S., Martin, Richard J.

“…Background Oxygen and continuous positive airway pressure (CPAP) are primary modes of respiratory support for preterm infants. Animal models, however, have…”
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Long-term effects of recurrent intermittent hypoxia and hyperoxia on respiratory system mechanics in neonatal mice by Dylag, Andrew M., Mayer, Catherine A., Raffay, Thomas M., Martin, Richard J., Jafri, Anjum, MacFarlane, Peter M.

“…Background: Premature infants are at increased risk for wheezing disorders. Clinically, these neonates experience recurrent episodes of apnea and desaturation…”
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Calcium-sensing receptor and CPAP-induced neonatal airway hyperreactivity in mice by Mayer, Catherine A., Roos, Benjamin, Teske, Jacob, Wells, Natalya, Martin, Richard J., Chang, Wenhan, Pabelick, Christina M., Prakash, Y. S., MacFarlane, Peter M.

“…Background Continuous positive airway pressure (CPAP) in preterm infants is initially beneficial, but animal models suggest longer term detrimental airway…”
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CPAP-induced airway hyper-reactivity in mice is modulated by hyaluronan synthase-3 by Mayer, Catherine A., Ganguly, Abhrajit, Mayer, Aubrey, Pabelick, Christina M., Prakash, Y. S., Hascall, Vince C., Midura, Ron J., Cali, Valbona, Flask, Christopher A., Erokwu, Bernadette O., Martin, Richard J., MacFarlane, Peter M.

“…Background Continuous positive airway pressure (CPAP) is a primary mode of respiratory support for preterm infants. Animal studies have shown long-term…”
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Increased airway reactivity in a neonatal mouse model of continuous positive airway pressure by Mayer, Catherine A., Martin, Richard J., MacFarlane, Peter M.

“…Background: Continuous positive airway pressure (CPAP) is a primary form of respiratory support used in the intensive care of preterm infants, but its…”
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Long-Term Effects of Recurrent Intermittent Hypoxia/Hyperoxia on Respiratory System Mechanics in Neonatal Mice by Dylag, Andrew M., Mayer, Catherine A., Martin, Richard, MacFarlane, Peter M.

“…Premature infants experiencing recurrent episodes of apnea exhibit frequent oxygen desaturation events. Resolving an event is often accompanied by increasing…”
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Acute lung injury in neonatal rats causes postsynaptic depression in nucleus tractus solitarii second-order neurons by Getsy, Paulina M., Mayer, Catherine A., MacFarlane, Peter M., Jacono, Frank J., Wilson, Christopher G.

“…•We studied the effects of acute lung injury in neonatal rats on synaptic efficacy of 2nd-order nTS neurons.•ALI significantly decreases amplitude of…”
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Vagal afferents modulate cytokine-mediated respiratory control at the neonatal medulla oblongata by Balan, Kannan V, Kc, Prabha, Hoxha, Zana, Mayer, Catherine A, Wilson, Christopher G, Martin, Richard J

“…Abstract Perinatal sepsis and inflammation trigger lung and brain injury in preterm infants, and associated apnea of prematurity. We hypothesized that…”
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Adenosine A2A receptors mediate GABAergic inhibition of respiration in immature rats by Mayer, Catherine A, Haxhiu, Musa A, Martin, Richard J, Wilson, Christopher G

“…1 Department of Pediatrics, Rainbow Babies and Children's Hospital, and Case Western Reserve University, Cleveland, Ohio; and 2 Department of Physiology and…”
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Lung and brainstem cytokine levels are associated with breathing pattern changes in a rodent model of acute lung injury by Jacono, Frank J, Mayer, Catherine A, Hsieh, Yee-Hsee, Wilson, Christopher G, Dick, Thomas E

“…Abstract Acute lung injury evokes a pulmonary inflammatory response and changes in the breathing pattern. The inflammatory response has a centrally mediated…”
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Intrapulmonary lipopolysaccharide exposure upregulates cytokine expression in the neonatal brainstem by Balan, Kannan V, Kc, Prabha, Mayer, Catherine A, Wilson, Christopher G, Belkadi, Abdelmadjid, Martin, Richard J

“…Perinatal inflammation and neonatal sepsis trigger lung and brain injury. We hypothesized that endotoxin exposure in the immature lung upregulates…”
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Airway Hyperreactivity Is Delayed after Mild Neonatal Hyperoxic Exposure by Onugha, Harris, MacFarlane, Peter M, Mayer, Catherine A, Abrah, Akua, Jafri, Anjum, Martin, Richard J

“…Wheezing disorders are prominent in former preterm infants beyond the neonatal period. We used a neonatal mouse model to investigate the time course of airway…”
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Effect of supplemental oxygen on reinitiation of breathing after neonatal resuscitation in rat pups by BOOKATZ, G. Bradley, MAYER, Catherine A, WILSON, Christopher G, VENTO, Maximo, GELFAND, Steven L, HAXHIU, Musa A, MARTIN, Richard J

“…To test our hypothesis that resuscitation with 21% and 40% oxygen (O2) would shorten time to onset of respiratory activity when compared with resuscitation…”
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Hyperbilirubinemia Diminishes Respiratory Drive in a Rat Pup Model by Mesner, Oded, Miller, Martha J, Iben, Sabine C, Prabha, KC, Mayer, Catherine A, Haxhiu, Musa A, Martin, Richard J

“…Although apnea is common in premature babies, there is a paucity of information concerning the pathophysiologic basis of these episodes and their relationship…”
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Allergic lung inflammation affects central noradrenergic control of cholinergic outflow to the airways in ferrets by Wilson, Christopher G, Akhter, Shamima, Mayer, Catherine A, Kc, Prabha, Balan, Kannan V, Ernsberger, Paul, Haxhiu, Musa A

“…Departments of 1 Pediatrics, 2 Nutrition, 3 Anatomy, and 4 Medicine, Case Western Reserve University, School of Medicine, Cleveland, Ohio; and 5 Department of…”
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Chemical profile of vagal preganglionic motor cells innervating the airways in ferrets: the absence of noncholinergic neurons by Kc, Prabha, Mayer, Catherine A, Haxhiu, Musa A

“…1 Department of Physiology and Biophysics, Howard University College of Medicine, Washington, District of Columbia 20059; and Departments of 2 Pediatrics and 3…”
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Mutation in the myelin proteolipid protein gene alters BK and SK channel function in the caudal medulla by Mayer, Catherine A, Macklin, Wendy B, Avishai, Nanthawan, Balan, Kannan, Wilson, Christopher G, Miller, Martha J

“…Abstract Proteolipid protein ( Plp ) gene mutation in rodents causes severe CNS dysmyelination, early death, and lethal hypoxic ventilatory depression ( Miller…”
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