Search Results - "Mayeno, A N"

A Physiologically Based Pharmacokinetic Model for Capreomycin by REISFELD, B, METZLER, C. P, LYONS, M. A, MAYENO, A. N, BROOKS, E. J, DEGROOTE, M. A

“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
Get full text

Eosinophils Preferentially Use Bromide to Generate Halogenating Agents by Mayeno, A N, Curran, A J, Roberts, R L, Foote, C S

“…Human eosinophils preferentially utilize bromide to generate a brominating agent, even at physiological halide concentrations, where chloride (140 mM) is over…”
Get full text

Characterization of "Peak E," a Novel Amino Acid Associated with Eosinophilia-Myalgia Syndrome by Mayeno, Arthur N., Lin, Feng, Foote, Christopher S., Loegering, David A., Ames, Matthew M., Hedberg, Craig W., Gleich, Gerald J.

“…Epidemiologic studies strongly associate eosinophilia-myalgia syndrome (EMS) with ingestion of tryptophan containing a contaminant ("peak E"). Prior reports…”
Get full text

Lidocaine in bronchoalveolar lavage fluid (BALF) is an inhibitor of eosinophil‐active cytokines by OHNISHI, T., KITA, H., MAYENO, A. N., OKADA, S., SUR, S., BROIDE, D. H., GLEICH, G. J.

“…Eosinophils and eosinophil granule proteins may play an important role in the pathogenesis of asthma. BALF from 40 patients with symptomatic asthma were…”
Get full text

Granule-associated flavin adenine dinucleotide (FAD) is responsible for eosinophil autofluorescence by Mayeno, A N, Hamann, K J, Gleich, G J

“…Unstained human eosinophils exhibit marked autofluorescence in comparison to other leukocytes due to a granule-associated fluorescent substance. Fluorescence…”
Get more information

investigation of the cause of the eosinophilia-myalgia syndrome associated with tryptophan use by Belongia, E.A, Hedberg, C.W, Gleich, G.J, White, K.E, Mayeno, A.N, Loegering, D.A, Dunnette, S.L, Pirie, P.L, MacDonald, K.L, Osterholm, M.T

“…Background. The eosinophilia-myalgia syndrome is a newly recognized illness that has been associated with the consumption of tryptophan products. It is not…”
Get full text

Eosinophilia-myalgia syndrome and tryptophan production: a cautionary tale by Mayeno, A N, Gleich, G J

“…An epidemic of a new disease, termed eosinophilia-myalgia syndrome, occurred in the USA in 1989. This syndrome was linked to the consumption of L-tryptophan…”
Get more information

3-(Phenylamino)alanine, a novel aniline-derived amino acid associated with the eosinophilia-myalgia syndrome: a link to the toxic oil syndrome? by Mayeno, A N, Belongia, E A, Lin, F, Lundy, S K, Gleich, G J

“…The eosinophilia-myalgia syndrome (EMS) is an inflammatory disease that occurred in epidemic proportions in the United States during 1989. Cases of EMS were…”
Get more information

On-line HPLC-tandem mass spectrometry analysis of contaminants of l-tryptophan associated with the onset of the eosinophilia-myalgia syndrome by Williamson, Brian L, Benson, Linda M, Tomlinson, Andy J, Mayeno, Arthur N, Gleich, Gerald J, Naylor, Stephen

“…The structural characterization of a number of contaminants of l-tryptophan (Trp) associated with eosinophilia myalgia syndrome has been performed for the…”
Get full text

1,1'-Ethylidenebis-[tryptophan] induces pathologic alterations in muscle similar to those observed in the eosinophilia-myalgia syndrome by EMSLIE-SMITH, A. M, MAYENO, A. N, NAKANO, S, GLEICH, G. J, ENGEL, A. G

“…1,1'-Ethylidenebis[tryptophan] (EBT), a derivative of L-tryptophan (LT), is a trace contaminant in batches of LT implicated by epidemiologic evidence in the…”
Get full text

Studies with 1,1'-ethylidenebis(tryptophan), a contaminant associated with L-tryptophan implicated in the eosinophilia-myalgia syndrome by Sidransky, H, Verney, E, Cosgrove, J W, Latham, P S, Mayeno, A N

“…L-Tryptophan binds to a rat liver nuclear envelope protein, and this binding is saturable, stereospecific, and of high affinity. Utilizing an in vitro assay of…”
Get more information

EBT, a tryptophan contaminant associated with eosinophilia myalgia syndrome, is incorporated into proteins during translation as an amino acid analog by Buss, W C, Stepanek, J, Bankhurst, A D, Mayeno, A N, Pastuszyn, A, Peabody, D

“…The tryptophan dimer 1,1'-ethylidenebis[L-tryptophan] was identified as a contaminant of tryptophan preparations associated with Eosinophilia-Myalgia Syndrome…”
Get more information

Eosinophil-active cytokine from mononuclear cells cultured with L-tryptophan products: An unexpected consequence of endotoxin contamination by Kita, Hirohito, Mayeno, Arthur N., Weyand, Cornelia M., Goronzy, Jörg J., Weiler, Deborah A., Lundy, Steven K., Abrams, John S., Gleich, Gerald J.

“…Background: The eosinophilia-myalgia syndrome, caused by a contaminant or contaminants in epidemiologically implicated L-tryptophan products, is characterized…”
Get full text

Biotransformation of 3-(Phenylamino)-1,2-propanediol to 3-(Phenylamino)alanine: A Chemical Link between Toxic Oil Syndrome and Eosinophilia-Myalgia Syndrome by Mayeno, Arthur N, Benson, Linda M, Naylor, Stephen, Colberg-Beers, Marelisa, Puchalski, Jonathan T, Gleich, Gerald J

“…During late 1989, the eosinophilia-myalgia syndrome (EMS) developed as an epidemic in the United States, with numerous additional cases reported in several…”
Get full text

1,1'-Ethylidenebis[L-tryptophan], an impurity in L-tryptophan associated with eosinophilia-myalgia syndrome, stimulates type I collagen gene expression in human fibroblasts in vitro by Zangrilli, J G, Mayeno, A N, Vining, V, Varga, J

“…Eosinophilia-myalgia syndrome (EMS), a recently described inflammatory disorder characterized by myalgia, peripheral eosinophilia, and multisystem inflammation…”
Get more information

The eosinophilia-myalgia syndrome: lessons from Germany by Mayeno, A N, Gleich, G J

Get more information

The eosinophilia-myalgia syndrome and tryptophan by Belongia, E.A. (Minnesota Department of Health, Minneapolis, MN), Mayeno, A.N, Osterholm, M.T

“…This chapter examines the therapeutic use of tryptophan and the biochemistry and metabolism of this amino acid. It examines the risk factors for…”
Get full text

Computational Toxicology of Chloroform: Reverse Dosimetry Using Bayesian Inference, Markov Chain Monte Carlo Simulation, and Human Biomonitoring Data by Lyons, Michael A., Yang, Raymond S. H., Mayeno, Arthur N., Reisfeld, Brad

“…Background: One problem of interpreting population-based biomonitoring data is the reconstruction of corresponding external exposure in cases where no such…”
Get full text

Biochemical Reaction Network Modeling:  Predicting Metabolism of Organic Chemical Mixtures by Mayeno, Arthur N, Yang, Raymond S. H, Reisfeld, Brad

“…All organisms are exposed to multiple xenobiotics, through food, environmental contamination, and drugs. These xenobiotics often undergo biotransformation, a…”
Get full text

A novel, sensitive method for determining benzo[ a]pyrene-diones using high-performance liquid chromatography with post-column zinc reduction by Liao, Kai H., Mayeno, Arthur N., Reardon, Kenneth F., Yang, Raymond S.H.

“…A novel and sensitive high-performance liquid chromatography (HPLC) method was developed to analyze dione metabolites of benzo[ a]pyrene (BaP). Because…”
Get full text