Search Results - "Mayboroda, O A"

O-Glycomic and Proteomic Signatures of Spontaneous and Butyrate-Stimulated Colorectal Cancer Cell Line Differentiation by Madunić, K., Luijkx, Y.M.C.A., Mayboroda, O.A., Janssen, G.M.C., van Veelen, P.A., Strijbis, K., Wennekes, T., Lageveen-Kammeijer, G.S.M., Wuhrer, M.

“…Gut microbiota of the gastrointestinal tract provide health benefits to the human host via bacterial metabolites. Bacterial butyrate has beneficial effects on…”
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Urinary metabolites predict prolonged duration of delayed graft function in DCD kidney transplant recipients by Kostidis, S., Bank, J. R., Soonawala, D., Nevedomskaya, E., Kooten, C., Mayboroda, O. A., Fijter, J. W.

“…Extending kidney donor criteria, including donation after circulatory death (DCD), has resulted in increased rates of delayed graft function (DGF) and primary…”
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Metabolomic analysis of avocado fruits by GC-APCI-TOF MS: effects of ripening degrees and fruit varieties by Hurtado-Fernández, E., Pacchiarotta, T., Mayboroda, O. A., Fernández-Gutiérrez, A., Carrasco-Pancorbo, A.

“…In order to investigate avocado fruit ripening, nontargeted GC-APCI-TOF MS metabolic profiling analyses were carried out. Principal component analysis (PCA)…”
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Derivatization of the tricarboxylic acid cycle intermediates and analysis by online solid-phase extraction-liquid chromatography–mass spectrometry with positive-ion electrospray ionization by Kloos, D., Derks, R.J.E., Wijtmans, M., Lingeman, H., Mayboroda, O.A., Deelder, A.M., Niessen, W.M.A., Giera, M.

“…The analysis of cellular metabolic processes is of fundamental biological interest. Cellular metabolites, such as the intermediates of the tricarboxylic acid…”
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A cross-platform metabolomics workflow for volume-restricted tissue samples: application to an animal model for polycystic kidney disease by Sánchez-López, E, Happé, H, Steenvoorden, E, Crego, A L, Marina, M L, Peters, D J M, Mayboroda, O A

“…Metabolic profiling provides an unbiased view of the physiological status of an organism as a "function" of the metabolic composition of a measured sample…”
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Urokinase Activates the Jak/Stat Signal Transduction Pathway in Human Vascular Endothelial Cells by Dumler, Inna, Kopmann, Angela, Weis, Angelika, Mayboroda, Oleg A, Wagner, Kai, Gulba, Dietrich C, Haller, Hermann

“…Endothelial cells demonstrate high urokinase expression and upregulation of urokinase receptors in response to vascular injury. Urokinase receptor binding…”
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HDL functionality in South Asians as compared to white Caucasians by Bakker, L.E.H, Boon, M.R, Annema, W, Dikkers, A, van Eyk, H.J, Verhoeven, A, Mayboroda, O.A, Jukema, J.W, Havekes, L.M, Meinders, A.E, Willems van Dijk, K, Jazet, I.M, Tietge, U.J.F, Rensen, P.C.N

“…Abstract Background and Aims South Asians have an exceptionally high risk of developing cardiovascular disease compared to white Caucasians. A contributing…”
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Urokinase-induced mitogenesis is mediated by casein kinase 2 and nucleolin by Dumler, I., Stepanova, V., Jerke, U., Mayboroda, O.A., Vogel, F., Bouvet, P., Tkachuk, V., Haller, H., Gulba, D.C.

“…Background: Urokinase (uPA) and the urokinase receptor (uPAR) form a multifunctional system capable of concurrently regulating pericellular proteolysis,…”
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Metabolic “footprints” of the circulating cancer mucins: CA125 in the high-grade ovarian cancer by Chagovets, VV, Vasil'ev, VG, Iurova, MV, Khabas, GN, Pavlovich, SV, Starodubtseva, NL, Mayboroda, OA

“…Mucins are large glycoproteins characterized by the abundant O-linked oligosaccharides (O-glycans) clustered on a protein backbone. Most of the circulating…”
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Upregulation of metabotropic glutamate receptor subtype mGluR3 and mGluR5 in reactive astrocytes in a rat model of mesial temporal lobe epilepsy by Aronica, Eleonora, Van Vliet, Erwin A., Mayboroda, Oleg A., Troost, Dirk, Da Silva, Fernando H. Lopes, Gorter, Jan A.

“…Reactive gliosis is a prominent morphological feature of mesial temporal lobe epilepsy. Because astrocytes express glutamate receptors, we examined changes in…”
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Colorectal cancer cell lines show striking diversity of their O-glycome reflecting the cellular differentiation phenotype by Madunić, Katarina, Zhang, Tao, Mayboroda, Oleg A., Holst, Stephanie, Stavenhagen, Kathrin, Jin, Chunsheng, Karlsson, Niclas G., Lageveen-Kammeijer, Guinevere S. M., Wuhrer, Manfred

“…Alterations in protein glycosylation in colorectal cancer (CRC) have been extensively studied using cell lines as models. However, little is known about their…”
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Urokinase Induces Activation and Formation of Stat4 and Stat1-Stat2 Complexes in Human Vascular Smooth Muscle Cells by Dumler, Inna, Kopmann, Angela, Wagner, Kai, Mayboroda, Oleg A., Jerke, Uwe, Dietz, Rainer, Haller, Hermann, Gulba, Dietrich C.

“…Urokinase-type plasminogen activator (uPA) and its specific receptor (uPAR) act in concert to stimulate cytoplasmic signaling machinery and transcription…”
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Analysis of biologically-active, endogenous carboxylic acids based on chromatography-mass spectrometry by Kloos, D., Lingeman, H., Mayboroda, O.A., Deelder, A.M., Niessen, W.M.A., Giera, M.

“…•Analysis of fatty acids, eicosanoids, small carboxylic acids and bile acids.•We explain the pitfalls and the advantages of LC-MS and GC-MS platforms.•Overview…”
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A new approach for fluorescence correlation spectroscopy (FCS) based immunoassays by Mayboroda, Oleg A., van Remoortere, Alexandra, Tanke, Hans J., Hokke, Cornelis H., Deelder, André M.

“…Fluorescence correlation spectroscopy (FCS) is a powerful technique for measuring physicochemical properties, such as concentration and diffusion constant, of…”
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Biliary Microbiota and Bile Acid Composition in Cholelithiasis by Saltykova, Irina V., Sazonov, Alexey E., Merzlikin, Nikolay V., Knyazeva, Elena M., Derks, Rico, Fernández-Peralbo, María A., Petrov, Vyacheslav A., Mayboroda, Oleg A.

“…Background. A functional interplay between BAs and microbial composition in gut is a well-documented phenomenon. In bile, this phenomenon is far less studied,…”
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Mild and selective labeling of malondialdehyde with 2-aminoacridone: assessment of urinary malondialdehyde levels by Giera, Martin, Kloos, Dick-Paul, Raaphorst, Alex, Mayboroda, Oleg A, Deelder, André M, Lingeman, Henk, Niessen, Wilfried M A

“…Malondialdehyde (MDA) has become a well-established biomarker for oxidative stress. The most commonly used way to determine urinary MDA levels is the…”
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The Jak/Stat Pathway and Urokinase Receptor Signaling in Human Aortic Vascular Smooth Muscle Cells by Dumler, Inna, Weis, Angelika, Mayboroda, Oleg A., Maasch, Christian, Jerke, Uwe, Haller, Hermann, Gulba, Dietrich C.

“…The binding of urokinase plasminogen activator (uPA) to its specific receptor (uPAR) facilitates migration of vascular smooth muscle cells (VSMC). However, the…”
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1H-NMR metabolic profiling of cerebrospinal fluid in patients with complex regional pain syndrome–related dystonia by Meissner, Axel, van der Plas, Anton A., van Dasselaar, Nick T., Deelder, André M., van Hilten, Jacobus J., Mayboroda, Oleg A.

“…1H-NMR spectroscopy-based, exploratory metabolomics analysis of cerebrospinal fluid of patients with complex regional pain syndrome–related dystonia suggests a…”
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The feasibility of MS and advanced data processing for monitoring Schistosoma mansoni infection by Balog, Crina I. A., Alexandrov, Theodore, Derks, Rico J., Hensbergen, Paul J., van Dam, Govert J., Tukahebwa, Edridah M., Kabatereine, Narcis B., Thiele, Herbert, Vennervald, Birgitte J., Mayboroda, Oleg A., Deelder, André M.

“…Purpose: Sensitive diagnosis, monitoring of disease progression and the evaluation of chemotherapeutic interventions are of prime importance for the…”
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Explorative Analysis of Urine by Capillary Electrophoresis-Mass Spectrometry in Chronic Patients with Complex Regional Pain Syndrome by Ramautar, Rawi, van der Plas, Anton A, Nevedomskaya, Ekaterina, Derks, Rico J. E, Somsen, Govert W, de Jong, Gerhardus J, van Hilten, Jacobus J, Deelder, André M, Mayboroda, Oleg A

“…Complex Regional Pain Syndrome (CRPS) is characterized by various combinations of sensory, autonomic and motor disturbances. Pain disproportionate to the…”
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