Search Results - "Mayberg, Helen S"

Stuck in a rut: rethinking depression and its treatment by Holtzheimer, Paul E, Mayberg, Helen S

“…The current definition of major depressive disorder (MDD) emerged from efforts to create reliable diagnostic criteria for clinical and research use. However,…”
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MicroRNA 135 Is Essential for Chronic Stress Resiliency, Antidepressant Efficacy, and Intact Serotonergic Activity by Issler, Orna, Haramati, Sharon, Paul, Evan D., Maeno, Hiroshi, Navon, Inbal, Zwang, Rayya, Gil, Shosh, Mayberg, Helen S., Dunlop, Boadie W., Menke, Andreas, Awatramani, Rajeshwar, Binder, Elisabeth B., Deneris, Evan S., Lowry, Christopher A., Chen, Alon

“…The link between dysregulated serotonergic activity and depression and anxiety disorders is well established, yet the molecular mechanisms underlying these…”
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Time for united action on depression: a Lancet–World Psychiatric Association Commission by Herrman, Helen, Patel, Vikram, Kieling, Christian, Berk, Michael, Buchweitz, Claudia, Cuijpers, Pim, Furukawa, Toshiaki A, Kessler, Ronald C, Kohrt, Brandon A, Maj, Mario, McGorry, Patrick, Reynolds, Charles F, Weissman, Myrna M, Chibanda, Dixon, Dowrick, Christopher, Howard, Louise M, Hoven, Christina W, Knapp, Martin, Mayberg, Helen S, Penninx, Brenda W J H, Xiao, Shuiyuan, Trivedi, Madhukar, Uher, Rudolf, Vijayakumar, Lakshmi, Wolpert, Miranda

“…[...]depression is a heterogeneous entity experienced with various combinations of signs and symptoms, severity levels, and longitudinal trajectories…”
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Targeting abnormal neural circuits in mood and anxiety disorders: from the laboratory to the clinic by Ressler, Kerry J, Mayberg, Helen S

“…Recent decades have witnessed tremendous advances in the neuroscience of emotion, learning and memory, and in animal models for understanding depression and…”
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Deep brain stimulation for psychiatric disorders by Holtzheimer, Paul E, Mayberg, Helen S

“…Medications, psychotherapy, and other treatments are effective for many patients with psychiatric disorders. However, with currently available interventions, a…”
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Resting-state connectivity biomarkers define neurophysiological subtypes of depression by Drysdale, Andrew T, Grosenick, Logan, Downar, Jonathan, Dunlop, Katharine, Mansouri, Farrokh, Meng, Yue, Fetcho, Robert N, Zebley, Benjamin, Oathes, Desmond J, Etkin, Amit, Schatzberg, Alan F, Sudheimer, Keith, Keller, Jennifer, Mayberg, Helen S, Gunning, Faith M, Alexopoulos, George S, Fox, Michael D, Pascual-Leone, Alvaro, Voss, Henning U, Casey, BJ, Dubin, Marc J, Liston, Conor

“…Using functional MRI in a large multisite sample of more that 1,000 patients, four distinct neurophysiological biotypes of depression are defined. These…”
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A whole brain fMRI atlas generated via spatially constrained spectral clustering by Craddock, R. Cameron, James, G.Andrew, Holtzheimer III, Paul E., Hu, Xiaoping P., Mayberg, Helen S.

“…Connectivity analyses and computational modeling of human brain function from fMRI data frequently require the specification of regions of interests (ROIs)…”
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Defining Critical White Matter Pathways Mediating Successful Subcallosal Cingulate Deep Brain Stimulation for Treatment-Resistant Depression by Riva-Posse, Patricio, Choi, Ki Sueng, Holtzheimer, Paul E, McIntyre, Cameron C, Gross, Robert E, Chaturvedi, Ashutosh, Crowell, Andrea L, Garlow, Steven J, Rajendra, Justin K, Mayberg, Helen S

“…Background Subcallosal cingulate white matter (SCC) deep brain stimulation (DBS) is an evolving investigational treatment for depression. Mechanisms of action…”
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Decreased Cortical Representation of Genital Somatosensory Field After Childhood Sexual Abuse by Heim, Christine M., Mayberg, Helen S., Mletzko, Tanja, Nemeroff, Charles B., Pruessner, Jens C.

“…ObjectiveSexual dysfunction is a common clinical symptom in women who were victims of childhood sexual abuse. The precise mechanism that mediates this…”
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A Shared Vision for Machine Learning in Neuroscience by Vu, Mai-Anh T, Adalı, Tülay, Ba, Demba, Buzsáki, György, Carlson, David, Heller, Katherine, Liston, Conor, Rudin, Cynthia, Sohal, Vikaas S, Widge, Alik S, Mayberg, Helen S, Sapiro, Guillermo, Dzirasa, Kafui

“…With ever-increasing advancements in technology, neuroscientists are able to collect data in greater volumes and with finer resolution. The bottleneck in…”
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Deep Brain Stimulation for Treatment-Resistant Depression: Follow-Up After 3 to 6 Years by Kennedy, Sidney H., Giacobbe, Peter, Rizvi, Sakina J., Placenza, Franca M., Nishikawa, Yasunori, Mayberg, Helen S., Lozano, Andres M.

“…Objective:A prevalence of at least 30% for treatment-resistant depression has prompted the investigation of alternative treatment strategies. Deep brain…”
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Receptor architecture of human cingulate cortex: Evaluation of the four-region neurobiological model by Palomero-Gallagher, Nicola, Vogt, Brent A., Schleicher, Axel, Mayberg, Helen S., Zilles, Karl

“…The structural and functional organization of the human cingulate cortex is an ongoing focus; however, human imaging studies continue to use the century‐old…”
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Disease state prediction from resting state functional connectivity by Craddock, R. Cameron, Holtzheimer III, Paul E., Hu, Xiaoping P., Mayberg, Helen S.

“…The application of multivoxel pattern analysis methods has attracted increasing attention, particularly for brain state prediction and real‐time functional MRI…”
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Metabolomic and inflammatory signatures of symptom dimensions in major depression by Brydges, Christopher R., Bhattacharyya, Sudeepa, Dehkordi, Siamak Mahmoudian, Milaneschi, Yuri, Penninx, Brenda, Jansen, Rick, Kristal, Bruce S., Han, Xianlin, Arnold, Matthias, Kastenmüller, Gabi, Bekhbat, Mandakh, Mayberg, Helen S, Craighead, W. Edward, Rush, A John, Fiehn, Oliver, Dunlop, Boadie W, Kaddurah-Daouk, Rima

“…•Major depressive disorder (MDD) can be theorized as a series of symptom dimensions.•We examined metabolic associations of three MDD symptom…”
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A multicenter pilot study of subcallosal cingulate area deep brain stimulation for treatment-resistant depression by Lozano, Andres M, Giacobbe, Peter, Hamani, Clement, Rizvi, Sakina J, Kennedy, Sidney H, Kolivakis, Theodore T, Debonnel, Guy, Sadikot, Abbas F, Lam, Raymond W, Howard, Andrew K, Ilcewicz-Klimek, Magda, Honey, Christopher R, Mayberg, Helen S

“…Deep brain stimulation (DBS) has been recently investigated as a treatment for major depression. One of the proposed targets for this application is the…”
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Effects of Patient Preferences on Outcomes in the Predictors of Remission in Depression to Individual and Combined Treatments (PReDICT) Study by Dunlop, Boadie W, Kelley, Mary E, Aponte-Rivera, Vivianne, Mletzko-Crowe, Tanja, Kinkead, Becky, Ritchie, James C, Nemeroff, Charles B, Craighead, W. Edward, Mayberg, Helen S

“…Objective:The Predictors of Remission in Depression to Individual and Combined Treatments [PReDICT] study aimed to identify clinical and biological factors…”
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Intraoperative neural signals predict rapid antidepressant effects of deep brain stimulation by Sendi, Mohammad S. E., Waters, Allison C., Tiruvadi, Vineet, Riva-Posse, Patricio, Crowell, Andrea, Isbaine, Faical, Gale, John T., Choi, Ki Sueng, Gross, Robert E., S. Mayberg, Helen, Mahmoudi, Babak

“…Deep brain stimulation (DBS) of the subcallosal cingulate (SCC) is a promising intervention for treatment-resistant depression (TRD). Despite the failure of a…”
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Pretreatment Brain States Identify Likely Nonresponse to Standard Treatments for Depression by McGrath, Callie L, Kelley, Mary E, Dunlop, Boadie W, Holtzheimer III, Paul E, Craighead, W. Edward, Mayberg, Helen S

“…Background Treatment approaches for major depressive disorder (MDD) result in approximately one third of patients achieving remission after a first treatment…”
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Establishing Evidence for Clinical Utility of a Neuroimaging Biomarker in Major Depressive Disorder: Prospective Testing and Implementation Challenges by Kelley, Mary E., Choi, Ki Sueng, Rajendra, Justin K., Craighead, W. Edward, Rakofsky, Jeffrey J., Dunlop, Boadie W., Mayberg, Helen S.

“…Although a number of neuroimaging biomarkers for response have been proposed, none have been tested prospectively for direct effects on treatment outcomes. To…”
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Default mode network connectivity change corresponds to ketamine’s delayed glutamatergic effects by Li, Meng, Woelfer, Marie, Colic, Lejla, Safron, Adam, Chang, Catie, Heinze, Hans-Jochen, Speck, Oliver, Mayberg, Helen S., Biswal, Bharat B., Salvadore, Giacomo, Fejtova, Anna, Walter, Martin

“…Ketamine exerts rapid antidepressant effects peaking 24 h after a single infusion, which have been suggested to be reflected by both reduced functional…”
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