Search Results - "May-Britt Tessem"

FunHoP analysis reveals upregulation of mitochondrial genes in prostate cancer by Rise, Kjersti, Tessem, May-Britt, Drabløs, Finn, Rye, Morten Beck

“…Mitochondrial activity in cancer cells has been central to cancer research since Otto Warburg first published his thesis on the topic in 1956. Although Warburg…”
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Prediction of recurrence from metabolites and expression of TOP2A and EZH2 in prostate cancer patients treated with radiotherapy by Hansen, Ailin Falkmo, Høiem, Therese Stork, Selnæs, Kirsten Margrete, Bofin, Anna Mary, Størkersen, Øystein, Bertilsson, Helena, Wright, Alan J., Giskeødegård, Guro Fanneløb, Bathen, Tone Frost, Rye, Morten Beck, Tessem, May‐Britt

“…Background The dual upregulation of TOP2A and EZH2 gene expression has been proposed as a biomarker for recurrence in prostate cancer patients to be treated…”
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An optimized MALDI MSI protocol for spatial detection of tryptic peptides in fresh frozen prostate tissue by Høiem, Therese S., Andersen, Maria K., Martin‐Lorenzo, Marta, Longuespée, Rémi, Claes, Britt S.R., Nordborg, Anna, Dewez, Frédéric, Balluff, Benjamin, Giampà, Marco, Sharma, Animesh, Hagen, Lars, Heeren, Ron M.A., Bathen, Tone F., Giskeødegård, Guro F., Krossa, Sebastian, Tessem, May‐Britt

“…MALDI MS imaging (MSI) is a powerful analytical tool for spatial peptide detection in heterogeneous tissues. Proper sample preparation is crucial to achieve…”
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NMR‐based metabolomics of biofluids in cancer by Giskeødegård, Guro F., Madssen, Torfinn S., Euceda, Leslie R., Tessem, May‐Britt, Moestue, Siver A., Bathen, Tone F.

“…Metabolomics is the branch of “omics” technologies that involves high‐throughput identification and quantification of small‐molecule metabolites in the…”
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Integrative metabolic and transcriptomic profiling of prostate cancer tissue containing reactive stroma by Andersen, Maria K., Rise, Kjersti, Giskeødegård, Guro F., Richardsen, Elin, Bertilsson, Helena, Størkersen, Øystein, Bathen, Tone F., Rye, Morten, Tessem, May-Britt

“…Reactive stroma is a tissue feature commonly observed in the tumor microenvironment of prostate cancer and has previously been associated with more aggressive…”
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Spermine and citrate as metabolic biomarkers for assessing prostate cancer aggressiveness by Giskeødegård, Guro F, Bertilsson, Helena, Selnæs, Kirsten M, Wright, Alan J, Bathen, Tone F, Viset, Trond, Halgunset, Jostein, Angelsen, Anders, Gribbestad, Ingrid S, Tessem, May-Britt

“…Separating indolent from aggressive prostate cancer is an important clinical challenge for identifying patients eligible for active surveillance, thereby…”
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DNA methylation changes in response to neoadjuvant chemotherapy are associated with breast cancer survival by Pedersen, Christine Aaserad, Cao, Maria Dung, Fleischer, Thomas, Rye, Morten B, Knappskog, Stian, Eikesdal, Hans Petter, Lanning, Per Eystein, Tost, Jörg, Kristensen, Vessela N, Tessem, May-Britt, Giskeadegård, Guro F, Bathen, Tone F

“…Background Locally advanced breast cancer is a heterogeneous disease with respect to response to neoadjuvant chemotherapy (NACT) and survival. It is currently…”
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Simultaneous Detection of Zinc and Its Pathway Metabolites Using MALDI MS Imaging of Prostate Tissue by Andersen, Maria K, Krossa, Sebastian, Høiem, Therese S, Buchholz, Rebecca, Claes, Britt S. R, Balluff, Benjamin, Ellis, Shane R, Richardsen, Elin, Bertilsson, Helena, Heeren, Ron M. A, Bathen, Tone F, Karst, Uwe, Giskeødegård, Guro F, Tessem, May-Britt

“…Levels of zinc, along with its mechanistically related metabolites citrate and aspartate, are widely reported as reduced in prostate cancer compared to healthy…”
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SFRP4 gene expression is increased in aggressive prostate cancer by Sandsmark, Elise, Andersen, Maria K., Bofin, Anna M., Bertilsson, Helena, Drabløs, Finn, Bathen, Tone F., Rye, Morten B., Tessem, May-Britt

“…Increased knowledge of the molecular differences between indolent and aggressive prostate cancer is needed for improved risk stratification and treatment…”
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FunHoP: Enhanced Visualization and Analysis of Functionally Homologous Proteins in Complex Metabolic Networks by Rise, Kjersti, Tessem, May-Britt, Drabløs, Finn, Rye, Morten B.

“…Cytoscape is often used for visualization and analysis of metabolic pathways. For example, based on KEGG data, a reader for KEGG Markup Language (KGML) is used…”
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Magnetic Resonance Metabolomics of Intact Tissue: A Biotechnological Tool in Cancer Diagnostics and Treatment Evaluation by BATHEN, Tone F, SITTER, Beathe, SJOBAKK, Torill E, TESSEM, May-Britt, GRIBBESTAD, Ingrid S

“…Personalized medicine is increasingly important in cancer treatment for its role in staging and its potential to improve stratification of patients. Different…”
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HR MAS MR spectroscopy in metabolic characterization of cancer by Moestue, Siver, Sitter, Beathe, Bathen, Tone Frost, Tessem, May-Britt, Gribbestad, Ingrid Susann

“…One of the central hallmarks of cancer is the rapid and infinite cellular proliferation. In order to cope with increased requirement for building blocks and…”
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Evaluation of lactate and alanine as metabolic biomarkers of prostate cancer using 1H HR-MAS spectroscopy of biopsy tissues by Tessem, May-Britt, Swanson, Mark G., Keshari, Kayvan R., Albers, Mark J., Joun, David, Tabatabai, Z. Laura, Simko, Jeffry P., Shinohara, Katsuto, Nelson, Sarah J., Vigneron, Daniel B., Gribbestad, Ingrid S., Kurhanewicz, John

“…The goal of this study was to investigate the use of lactate and alanine as metabolic biomarkers of prostate cancer using 1H high‐resolution magic angle…”
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A Balanced Tissue Composition Reveals New Metabolic and Gene Expression Markers in Prostate Cancer by Tessem, May-Britt, Bertilsson, Helena, Angelsen, Anders, Bathen, Tone F, Drabløs, Finn, Rye, Morten Beck

“…Molecular analysis of patient tissue samples is essential to characterize the in vivo variability in human cancers which are not accessible in cell-lines or…”
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Spatially matched in vivo and ex vivo MR metabolic profiles of prostate cancer - investigation of a correlation with Gleason score by Selnæs, Kirsten M., Gribbestad, Ingrid S., Bertilsson, Helena, Wright, Alan, Angelsen, Anders, Heerschap, Arend, Tessem, May-Britt

“…MR metabolic profiling of the prostate is promising as an additional diagnostic approach to separate indolent from aggressive prostate cancer. The objective of…”
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A new method to provide a fresh frozen prostate slice suitable for gene expression study and MR spectroscopy by Bertilsson, Helena, Angelsen, Anders, Viset, Trond, Skogseth, Haakon, Tessem, May-Britt, Halgunset, Jostein

“…BACKGROUND Fresh frozen tissue from radical prostatectomy specimens is highly valuable material for research on gene expression and cellular metabolites. The…”
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High-resolution magic angle spinning (HR MAS) MR spectroscopy in metabolic characterization of human cancer by Sitter, Beathe, Bathen, Tone F., Tessem, May-Britt, Gribbestad, Ingrid S.

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Cholesterol synthesis pathway genes in prostate cancer are transcriptionally downregulated when tissue confounding is minimized by Rye, Morten Beck, Bertilsson, Helena, Andersen, Maria K, Rise, Kjersti, Bathen, Tone F, Drabløs, Finn, Tessem, May-Britt

“…The relationship between cholesterol and prostate cancer has been extensively studied for decades, where high levels of cellular cholesterol are generally…”
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The effect of sampling procedures and day-to-day variations in metabolomics studies of biofluids by Giskeødegård, Guro F., Andreassen, Trygve, Bertilsson, Helena, Tessem, May-Britt, Bathen, Tone F.

“…Metabolomics analysis of biofluids is a feasible tool for disease characterization and monitoring due to its minimally invasive nature. To reduce unwanted…”
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Sample Preparation for Metabolite Detection in Mass Spectrometry Imaging by Andersen, Maria K, Giampà, Marco, Midtbust, Elise, Høiem, Therese S, Krossa, Sebastian, Tessem, May-Britt

“…Metabolites reflect the biological state of cells and tissue, and metabolomics is therefore a field of high interest both to understand normal physiological…”
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