Search Results - "May, Sean T"
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Brassinosteroids participate in the control of basal and acquired freezing tolerance of plants
Published in Proceedings of the National Academy of Sciences - PNAS (04-10-2016)“…Brassinosteroids (BRs) are growth-promoting plant hormones that play a role in abiotic stress responses, but molecular modes that enable this activity remain…”
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The Response of the Human Umbilical Vein Endothelial Cell Transcriptome to Variation in Magnesium Concentration
Published in Nutrients (31-08-2022)“…Vascular endothelial cells have a critical role in the maintenance of cardiovascular function. Evidence suggests that endothelial function may be compromised…”
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Repurposing Antibacterial AM404 as a Potential Anticancer Drug for Targeting Colorectal Cancer Stem-Like Cells
Published in Cancers (31-12-2019)“…Tumour-promoting inflammation is involved in colorectal cancer (CRC) development and therapeutic resistance. However, the antibiotics and antibacterial drugs…”
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Yeast m6A Methylated mRNAs Are Enriched on Translating Ribosomes during Meiosis, and under Rapamycin Treatment
Published in PloS one (17-07-2015)“…Interest in mRNA methylation has exploded in recent years. The sudden interest in a 40 year old discovery was due in part to the finding of FTO's (Fat Mass…”
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How to decide? Different methods of calculating gene expression from short oligonucleotide array data will give different results
Published in BMC bioinformatics (15-03-2006)“…Short oligonucleotide arrays for transcript profiling have been available for several years. Generally, raw data from these arrays are analysed with the aid of…”
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Paternal low protein diet perturbs inter-generational metabolic homeostasis in a tissue-specific manner in mice
Published in Communications biology (08-09-2022)“…The underlying mechanisms driving paternally-programmed metabolic disease in offspring remain poorly defined. We fed male C57BL/6 mice either a control normal…”
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CG7379 and ING1 suppress cancer cell invasion by maintaining cell-cell junction integrity
Published in Open biology (08-09-2021)“…Approximately 90% of cancer-related deaths can be attributed to a tumour's ability to spread. We have identified CG7379, the fly orthologue of human ING1, as a…”
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comparison of the Thlaspi caerulescens and Thlaspi arvense shoot transcriptomes
Published in The New phytologist (01-01-2006)“…• Whole-genome transcriptome profiling is revealing how biological systems are regulated at the transcriptional level. This study reports the development of a…”
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Changes in gene expression in Arabidopsis shoots during phosphate starvation and the potential for developing smart plants
Published in Plant physiology (Bethesda) (01-06-2003)“…Our aim was to generate and prove the concept of "smart" plants to monitor plant phosphorus (P) status in Arabidopsis. Smart plants can be genetically…”
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Authentication of Coffee by Means of PCR-RFLP Analysis and Lab-on-a-Chip Capillary Electrophoresis
Published in Journal of agricultural and food chemistry (04-10-2006)“…Coffee is one of the most important world food commodities, commercial trade consisting almost entirely of Arabica and Robusta varieties. The former is…”
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Analysis of ripening-related gene expression in papaya using an Arabidopsis-based microarray
Published in BMC plant biology (21-12-2012)“…Papaya (Carica papaya L.) is a commercially important crop that produces climacteric fruits with a soft and sweet pulp that contain a wide range of health…”
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Heterologous oligonucleotide microarrays for transcriptomics in a non-model species; a proof-of-concept study of drought stress in Musa
Published in BMC genomics (16-09-2009)“…'Systems-wide' approaches such as microarray RNA-profiling are ideally suited to the study of the complex overlapping responses of plants to biotic and abiotic…”
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A Genetic Analysis of Tumor Progression in Drosophila Identifies the Cohesin Complex as a Suppressor of Individual and Collective Cell Invasion
Published in iScience (26-06-2020)“…Metastasis is the leading cause of death for patients with cancer. Consequently it is imperative that we improve our understanding of the molecular mechanisms…”
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Adaptive resistance is not responsible for long-term drug resistance in a cellular model of triple negative breast cancer
Published in Gene (20-01-2023)Get full text
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A Brassica exon array for whole-transcript gene expression profiling
Published in PloS one (16-09-2010)“…Affymetrix GeneChip® arrays are used widely to study transcriptional changes in response to developmental and environmental stimuli. GeneChip® arrays comprise…”
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MicroRNA-495/TGF-β/FOXC1 axis regulates multidrug resistance in metaplastic breast cancer cells
Published in Biochemical pharmacology (01-10-2021)“…[Display omitted] Triple-negative metaplastic breast carcinoma (MBC) poses a significant treatment challenge due to lack of targeted therapies and chemotherapy…”
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Susceptibility to experimental infection of the invertebrate locusts (Schistocerca gregaria) with the apicomplexan parasite Neospora caninum
Published in PeerJ (San Francisco, CA) (02-12-2014)“…Neuropathogenesis is a feature of Neospora caninum infection. In order to explore this in the absence of acquired host immunity to the parasite, we have tested…”
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Mast Cell Tryptase Release Contributes to Disease Progression in Lymphangioleiomyomatosis
Published in American journal of respiratory and critical care medicine (15-08-2021)“…Lymphangioleiomyomatosis is a multisystem disease causing lung cysts and respiratory failure. Loss of tuberous sclerosis complex (TSC) gene function results in…”
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Using genomic DNA-based probe-selection to improve the sensitivity of high-density oligonucleotide arrays when applied to heterologous species
Published in Plant methods (09-11-2005)“…High-density oligonucleotide (oligo) arrays are a powerful tool for transcript profiling. Arrays based on GeneChip technology are amongst the most widely used,…”
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Transcriptional effects of carbon and nitrogen starvation on Ganoderma boninense, an oil palm phytopathogen
Published in Molecular biology reports (01-12-2024)“…Background Ganoderma boninense is a phytopathogen of oil palm, causing basal and upper stem rot diseases. Methods The genome sequence was used as a reference…”
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