Search Results - "May, John M."

Biological characterization of a novel, orally active small molecule gonadotropin-releasing hormone (GnRH) antagonist using castrated and intact rats by Anderes, Kenna L, Luthin, David R, Castillo, Rosemary, Kraynov, Eugenia A, Castro, Mary, Nared-Hood, Karen, Gregory, Margaret L, Pathak, Ved P, Christie, Lance C, Paderes, Genevieve, Vazir, Haresh, Ye, Qiang, Anderson, Mark B, May, John M

“…Gonadotropin-releasing hormone (GnRH) receptor antagonists have potential in treating numerous hormone-dependent pathologies including cancers of the prostate,…”
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Characterization of mono- and diaminopyrimidine derivatives as novel, nonpeptide gonadotropin releasing hormone (GnRH) receptor antagonists by Luthin, David R, Hong, Yufeng, Tompkins, Eileen, Anderes, Kenna L, Paderes, Genevieve, Kraynov, Eugenia A, Castro, Mary A, Nared-Hood, Karen D, Castillo, Rosemary, Gregory, Margaret, Vazir, Haresh, May, John M, Anderson, Mark B

“…A novel series of derivatives of mono- and diaminopyrimidines 1 potently displaced binding of a radiolabeled GnRH analogue to human and rat GnRH receptors…”
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A study of the precursors leading to ‘organisational’ accidents in complex industrial settings by Taylor, Richard H., van Wijk, Lorenzo G.A., May, John H.M., Carhart, Neil J.

“…•12 accident investigations are analysed highlighting common organisational issues.•Statements of expectation are derived to address organisational learning…”
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The discovery of novel small molecule non-peptide gonadotropin releasing hormone (GnRH) receptor antagonists by Luthin, David R., Hong, Yufeng, Pathak, Ved P., Paderes, Genevieve, Nared-Hood, Karen D., Castro, Mary A., Vazir, Haresh, Li, Haitao, Tompkins, Eileen, Christie, Lance, May, John M., Anderson, Mark B.

“…A novel series of non-peptide derivatives 1, 14, and 15 that bind with high affinity to the human GnRH receptors is discussed. The discovery was made from…”
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Synthesis and biological activity of oxo-7H-benzo[E]perimidine-4-carboxylic acid derivatives as potent, nonpeptide corticotropin releasing factor (CRF) receptor antagonists by LUTHIN, D. R, RABINOVICH, A. K, BHUMRALKAR, D. R, YOUNGBLOOD, K. L, BYCHOWSKI, R. A, DHANOA, D. S, MAY, J. M

“…A novel series of derivatives of oxo-7H-benzo[e]perimidine-4-carboxylic acid (I) potently displaced radioligand binding of 125I-CRF to both CRF1 and CRF2…”
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Y1 and Y2 Receptor Selective Neuropeptide Y Analogs: Evidence for a Y1 Receptor Subclass by Kirby, Dean A, Koerber, Steven C, May, John M, Hagaman, Cristin, Cullen, Mary Jane, Pelleymounter, Mary Ann, Rivier, Jean E

“…Neuropeptide Y (NPY), a 36-residue polypeptide produced abundantly in both nervous and peripheral tissues, appears to play a significant role in the regulation…”
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A new look at cash, profit, growth, risk, and time by May, John M

“…The events and trends of 1974 caused traditional corporate objectives to be changed rather drastically, and the remaining years of the 1970s promise further…”
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Exendin is a Partial Agonist at the Human Glucagon-like Peptide-1 Receptor by KIEL, DAN, LAKIS, JAMES N, MAY, JOHN M

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Effect of testosterone suppression on the pharmacokinetics of a potent GnRH receptor antagonist by IATSIMIRSKAIA, Eugenia A, GREGORY, Margaret L, MAY, John M, ANDERES, Kenna L, CASTILLO, Rosemary, MILGRAM, K. Eric, LUTHIN, David R, PATHAK, Ved P, CHRISTIE, Lance C, VAZIR, Haresh, ANDERSON, Mark B

“…The expression of cytochrome P450 enzymes (CYPs) in animals and humans is under complex hormonal regulation. Chronic treatment with drugs that alter sex…”
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Synthesis and biological activity of oxo-7 H-benzo[ e]perimidine-4-carboxylic acid derivatives as potent, nonpeptide corticotropin releasing factor (CRF) receptor antagonists by Luthin, David R, Rabinovich, Aleksandr K, Bhumralkar, Dilip R, Youngblood, Kenna L, Bychowski, Richard A, Dhanoa, Daljit S, May, John M

“…A novel series of derivatives of oxo-7 H-benzo[ e]perimidine-4-carboxylic acid ( I) potently displaced radioligand binding of 125I-CRF to both CRF 1 and CRF 2…”
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Megestrol acetate-associated adrenal insufficiency by Bulchandani, Deepti, Nachnani, Jagdish, Amin, Alpesh, May, John

“…Megestrol acetate (MA) is commonly used to promote weight gain in malnourished elderly patients. Although adrenal insufficiency has been reported as an adverse…”
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Estimating the Occupational Morbidity for Migrant and Seasonal Farmworkers in New York State: A Comparison of Two Methods by Earle-Richardson, Giulia B., PhD, Brower, Melissa A., MPH, Jones, Amanda M., BA, May, John J., MD, Jenkins, Paul L., PhD

“…Purpose Compare occupational morbidity estimates for migrant and seasonal farmworkers obtained from survey methods versus chart review methods and estimate the…”
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In vitro phosphorylation of a synthetic collagen peptide by cyclic AMP-dependent protein kinase by Glass, D B, May, J M

“…A synthetic tridecapeptide that corresponds closely to amino acid residues 98 to 110 in chick collagen alpha 1(I) contains several determinants of specificity…”
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Advances in the Design, Analysis, and Manufacturing of Steel Leaf Springs by Wachtel, Douglas W., Adkins, David E., May, John M., Hohnstadt, William E.

“…New rear suspension springs were designed for the 1988 General Motors full-size pick-up truck. In order to meet the aggressive project goals for durability and…”
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Resveratrol: Twenty Years of Growth, Development and Controversy by Pezzuto, John M

“…Resveratrol was first isolated in 1939 by Takaoka from Veratrum grandiflorum O. Loes. Following this discovery, sporadic descriptive reports appeared in the…”
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Rethinking Community Policing by Ray, John M

“…Community policing is in decline, threatened with obsolescence by data-driven practices like COMPSTAT and Intelligence-Led Policing. Efficiency driven and…”
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Pyloric Functional Lumen Imaging Probe Measurements Are Dependent on Balloon Position by Brandon Yim, Lennon Gregor, Robert M Siwiec, Mohammad Al-haddad, Thomas V Nowak, John M Wo

“…Background/Aims The functional lumen imaging probe (FLIP) device has been used to assess pyloric dysfunction in patients with gastroparesis. We aim to…”
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Ectopic teeth with disparate migration: A literature review and new case series by Pallak Arora, Madhu K. Nair, Hui Liang, Paras B. Patel, John M. Wright, Mehrnaz Tahmasbi-Arashlow

“…Purpose: Ectopic eruption can be defined as the emergence of a tooth in an abnormal location, where the tooth does not follow its typical eruption pathway…”
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Risk factors for unexpected readmission and reoperation following open procedures for shoulder instability: a national database study of 1,942 cases by John M. Tarazi, Matthew J. Partan, Alton Daley, Brandon Klein, Luke Bartlett, Randy M. Cohn

“…Background: The purpose of this study was to identify demographics and risk factors associated with unplanned 30-day readmission and reoperation following open…”
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Risk factors for unexpected admission following arthroscopic and open treatment of shoulder instability: a national database study of 11,230 cases by Joshua Giordano, John M. Tarazi, Matthew J. Partan, Randy M. Cohn

“…Background: Shoulder instability procedures have low morbidity; however, complications can arise that result in readmission to an inpatient healthcare…”
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