Search Results - "Maxwell, Jack N."

Exploring the role of CITED transcriptional regulators in the control of macrophage polarization by Wiggins, Derek A, Maxwell, Jack N, Nelson, David E

“…Macrophages are tissue resident innate phagocytic cells that take on contrasting phenotypes, or polarization states, in response to the changing combination of…”
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WDR5 facilitates recruitment of N-MYC to conserved WDR5 gene targets in neuroblastoma cell lines by Bumpous, Leigh A., Moe, Kylie C., Wang, Jing, Carver, Logan A., Williams, Alexandria G., Romer, Alexander S., Scobee, Jesse D., Maxwell, Jack N., Jones, Cheyenne A., Chung, Dai H., Tansey, William P., Liu, Qi, Weissmiller, April M.

“…Collectively, the MYC family of oncoprotein transcription factors is overexpressed in more than half of all malignancies. The ability of MYC proteins to access…”
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The SWI/SNF ATPase BRG1 facilitates multiple pro-tumorigenic gene expression programs in SMARCB1-deficient cancer cells by Moe, Kylie C., Maxwell, Jack N., Wang, Jing, Jones, Cheyenne A., Csaki, Grace T., Florian, Andrea C., Romer, Alexander S., Bryant, Daniel L., Farone, Anthony L., Liu, Qi, Tansey, William P., Weissmiller, April M.

“…Malignant rhabdoid tumor (MRT) is driven by the loss of the SNF5 subunit of the SWI/SNF chromatin remodeling complex and then thought to be maintained by…”
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Multiple interactions of the oncoprotein transcription factor MYC with the SWI/SNF chromatin remodeler by Woodley, Chase M., Romer, Alexander S., Wang, Jing, Guarnaccia, Alissa D., Elion, David L., Maxwell, Jack N., Guerrazzi, Kiana, McCann, Tyler S., Popay, Tessa M., Matlock, Brittany K., Flaherty, David K., Lorey, Shelly L., Liu, Qi, Tansey, William P., Weissmiller, April M.

“…The SNF5 subunit of the SWI/SNF chromatin remodeling complex has been shown to act as a tumor suppressor through multiple mechanisms, including impairing the…”
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