Search Results - "Maxwell, George"

Gut microbiota changes are detected in asymptomatic very young children with SARS-CoV-2 infection by Nashed, Lydia, Mani, Jyoti, Hazrati, Sahel, Stern, David B, Subramanian, Poorani, Mattei, Lisa, Bittinger, Kyle, Hu, Weiming, Levy, Shira, Maxwell, George L, Hourigan, Suchitra K

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Programmed cortical ER collapse drives selective ER degradation and inheritance in yeast meiosis by Otto, George Maxwell, Cheunkarndee, Tia, Leslie, Jessica Mae, Brar, Gloria Ann

“…The endoplasmic reticulum (ER) carries out essential and conserved cellular functions, which depend on the maintenance of its structure and subcellular…”
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Seq-ing answers: uncovering the unexpected in global gene regulation by Otto, George Maxwell, Brar, Gloria Ann

“…The development of techniques for measuring gene expression globally has greatly expanded our understanding of gene regulatory mechanisms in depth and scale…”
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Genotype first: Clinical genomics research through a reverse phenotyping approach by Wilczewski, Caralynn M., Obasohan, Justice, Paschall, Justin E., Zhang, Suiyuan, Singh, Sumeeta, Maxwell, George L., Similuk, Morgan, Wolfsberg, Tyra G., Turner, Clesson, Biesecker, Leslie G., Katz, Alexander E.

“…Although genomic research has predominantly relied on phenotypic ascertainment of individuals affected with heritable disease, the falling costs of sequencing…”
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Utility of whole-genome sequencing for detection of newborn screening disorders in a population cohort of 1,696 neonates by Bodian, Dale L., Klein, Elisabeth, Iyer, Ramaswamy K., Wong, Wendy S.W., Kothiyal, Prachi, Stauffer, Daniel, Huddleston, Kathi C., Gaither, Amber D., Remsburg, Irina, Khromykh, Alina, Baker, Robin L., Maxwell, George L., Vockley, Joseph G., Niederhuber, John E., Solomon, Benjamin D.

“…To assess the potential of whole-genome sequencing (WGS) to replicate and augment results from conventional blood-based newborn screening (NBS)…”
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Integrated multi-omic analysis of low-grade ovarian serous carcinoma collected from short and long-term survivors by Wong, Kwong-Kwok, Bateman, Nicholas W, Ng, Chun Wai, Tsang, Yvonne T M, Sun, Charlotte S, Celestino, Joseph, Nguyen, Tri V, Malpica, Anais, Hillman, R Tyler, Zhang, Jianhua, Futreal, P Andrew, Rojas, Christine, Conrads, Kelly A, Hood, Brian L, Dalgard, Clifton L, Wilkerson, Matthew D, Phippen, Neil T, Conrads, Thomas P, Maxwell, George L, Sood, Anil K, Gershenson, David M

“…Low-grade serous ovarian cancer (LGSOC) is a rare disease that occurs more frequently in younger women than those with high-grade disease. The current…”
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Racial disparities in high-risk uterine cancer histologic subtypes: A United States Cancer Statistics study by Abel, Mary Kathryn, Liao, Cheng-I, Chan, Chloe, Lee, Danny, Rohatgi, Atharva, Darcy, Kathleen M., Tian, Chunqiao, Mann, Amandeep K., Maxwell, George L., Kapp, Daniel S., Chan, John K.

“…Black women with uterine cancer on average have worse survival outcomes compared to White women, in part due to higher rates of aggressive, non-endometrioid…”
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Route of myomectomy and fertility: a prospective cohort study by Wise, Lauren A., Thomas, Laine, Anderson, Sophia, Baird, Donna D., Anchan, Raymond M., Terry, Kathryn L., Marsh, Erica E., Wegienka, Ganesa, Nicholson, Wanda Kay, Wallace, Kedra, Bigelow, Robert, Spies, James, Maxwell, George L., Jacoby, Vanessa, Myers, Evan R., Stewart, Elizabeth A.

“…To assess prospectively the association between the myomectomy route and fertility. Prospective cohort study. The Comparing Treatments Options for Uterine…”
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The Comparing Options for Management: PAtient-centered REsults for Uterine Fibroids (COMPARE-UF) registry: rationale and design by Stewart, Elizabeth A., Lytle, Barbara L., Thomas, Laine, Wegienka, Ganesa R, Jacoby, Vanessa, Diamond, Michael P., Nicholson, Wanda K., Anchan, Raymond M., Venable, Sateria, Wallace, Kedra, Marsh, Erica E., Maxwell, George L., Borah, Bijan J., Catherino, William H., Myers, Evan R.

“…Uterine fibroids are common in premenopausal women, yet comparative effectiveness research on uterine fibroid treatments is rare. The purpose of this study was…”
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Ancestral characterization of 1018 cancer cell lines highlights disparities and reveals gene expression and mutational differences by Kessler, Michael D., Bateman, Nicholas W., Conrads, Thomas P., Maxwell, George L., Dunning Hotopp, Julie C., O’Connor, Timothy D.

“…Background Although cell lines are an essential resource for studying cancer biology, many are of unknown ancestral origin, and their use may not be optimal…”
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Genomic and molecular characterization of preterm birth by Knijnenburg, Theo A., Vockley, Joseph G., Chambwe, Nyasha, Gibbs, David L., Humphries, Crystal, Huddleston, Kathi C., Klein, Elisabeth, Kothiyal, Prachi, Tasseff, Ryan, Dhankani, Varsha, Bodian, Dale L., Wong, Wendy S. W., Glusman, Gustavo, Mauldin, Denise E., Miller, Michael, Slagel, Joseph, Elasady, Summer, Roach, Jared C., Kramer, Roger, Leinonen, Kalle, Linthorst, Jasper, Baveja, Rajiv, Baker, Robin, Solomon, Benjamin D., Eley, Greg, Iyer, Ramaswamy K., Maxwell, George L., Bernard, Brady, Shmulevich, Ilya, Hood, Leroy, Niederhuber, John E.

“…Preterm birth (PTB) complications are the leading cause of long-term morbidity and mortality in children. By using whole blood samples, we integrated…”
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Fear of recurrence, emotional well-being and quality of life among long-term advanced ovarian cancer survivors by Osann, Kathryn, Wenzel, Lari, McKinney, Chelsea, Wagner, Lynne, Cella, David, Fulci, Giulia, Scroggins, Mary J., Lankes, Heather A., Wang, Victoria, Nephew, Kenneth P., Maxwell, George L., Mok, Samuel C., Conrads, Thomas P., Miller, Austin, Birrer, Michael

“…Although advanced stage epithelial ovarian cancer is widely considered life-threatening, 17% of women with advanced disease will survive long-term. Little is…”
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Epidemiological and microbiome associations of Clostridioides difficile carriage in infancy and early childhood by Mani, Jyoti, Levy, Shira, Angelova, Angelina, Hazrati, Sahel, Fassnacht, Ryan, Subramanian, Poorani, Richards, Tiana, Niederhuber, John E., Maxwell, George L., Hourigan, Suchitra K.

“…There has been an increase in the prevalence of Clostridioides difficile (C. diff) causing significant economic impact on the health care system. Although…”
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ATP1A1-linked diseases require a malfunctioning protein product from one allele by Spontarelli, Kerri, Young, Victoria C., Sweazey, Ryan, Padro, Alexandria, Lee, Jeannie, Bueso, Tulio, Hernandez, Roberto M., Kim, Jongyeol, Katz, Alexander, Rossignol, Francis, Turner, Clesson, Wilczewski, Caralynn M., Maxwell, George L., Holmgren, Miguel, Bailoo, Jeremy D., Yano, Sho T., Artigas, Pablo

“…Heterozygous germline variants in ATP1A1, the gene encoding the α1 subunit of the Na+/K+-ATPase (NKA), have been linked to diseases including primary…”
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Clinical significance of homologous recombination deficiency score testing in endometrial Cancer by Siedel, Jean H., Ring, Kari L., Hu, Wei, Dood, Robert L., Wang, Ying, Baggerly, Keith, Darcy, Kathleen M., Conrads, Thomas P., Gallagher, Shannon, Tshiaba, Placede, Neff, Chris, Timms, Kirsten M., Mangala, Selanere, Westin, Shannon N., Broaddus, Russell, Lopez-Berestein, Gabriel, Lu, Karen H., Coleman, Robert L., Maxwell, George L., Sood, Anil K.

“…Homologous recombination deficiency (HRD) score is related to chemotherapy response in some cancers, but its role in endometrial cancer in not known. We…”
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Efficient identification of neoantigen-specific T-cell responses in advanced human ovarian cancer by Liu, Song, Matsuzaki, Junko, Wei, Lei, Tsuji, Takemasa, Battaglia, Sebastiano, Hu, Qiang, Cortes, Eduardo, Wong, Laiping, Yan, Li, Long, Mark, Miliotto, Anthony, Bateman, Nicholas W, Lele, Shashikant B, Chodon, Thinle, Koya, Richard C, Yao, Song, Zhu, Qianqian, Conrads, Thomas P, Wang, Jianmin, Maxwell, George L, Lugade, Amit A, Odunsi, Kunle

“…Efficient identification of neoantigen-specific T-cell responses in epithelial ovarian cancer (EOC) remains a challenge. Existing investigations of spontaneous…”
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Faecal zonulin, calprotectin and the infant microbiome in early life by Bacorn, Mickayla, Subramanian, Poorani, Levy, Shira, Chen, Qing, Maxwell, George L., Hourigan, Suchitra K

“…[...]their presence may indicate immune maturation in infants as opposed to pathology. [...]we investigated the relationship between zonulin, calprotectin and…”
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Quality of Life and Adverse Events: Prognostic Relationships in Long-Term Ovarian Cancer Survival by Wenzel, Lari, Osann, Kathryn, McKinney, Chelsea, Cella, David, Fulci, Giulia, Scroggins, Mary J, Lankes, Heather A, Wang, Victoria, Nephew, Kenneth P, Maxwell, George L, Mok, Samuel C, Conrads, Thomas P, Miller, Austin, Mannel, Robert S, Gray, Heidi J, Hanjani, Parviz, Huh, Warner K, Spirtos, Nick, Leitao, Mario M, Glaser, Gretchen, Sharma, Sudarshan K, Santin, Alessandro D, Sperduto, Paul, Lele, Shashikant B, Burger, Robert A, Monk, Bradley J, Birrer, Michael

“…Abstract Background There is a critical need to identify patient characteristics associated with long-term ovarian cancer survival. Methods Quality of life…”
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BPA Alters Estrogen Receptor Expression in the Heart After Viral Infection Activating Cardiac Mast Cells and T Cells Leading to Perimyocarditis and Fibrosis by Bruno, Katelyn Ann, Mathews, Jessica Elizabeth, Yang, Alex Lingyun, Frisancho, J. Augusto, Scott, Ashley Jennie, Greyner, Henry David, Molina, Frank Anthony, Greenaway, Merci Shekinah, Cooper, George Maxwell, Bucek, Adriana, Morales-Lara, Andrea Carolina, Hill, Anneliese Ruth, Mease, Anna Alisa, Di Florio, Damian Nicolas, Sousou, John Michael, Coronado, Alexandria Christine, Stafford, Allison Ray, Fairweather, DeLisa

“…Myocarditis is an inflammatory heart disease that leads to dilated cardiomyopathy (DCM) and heart failure. Sex hormones play an important role in the…”
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Differences in the number of de novo mutations between individuals are due to small family-specific effects and stochasticity by Goldmann, Jakob M, Hampstead, Juliet E, Wong, Wendy S W, Wilfert, Amy B, Turner, Tychele N, Jonker, Marianne A, Bernier, Raphael, Huynen, Martijn A, Eichler, Evan E, Veltman, Joris A, Maxwell, George L, Gilissen, Christian

“…The number of de novo mutations (DNMs) in the human germline is correlated with parental age at conception, but this explains only part of the observed…”
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