Search Results - "Maxson, Rob"
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Cyclic alopecia' in Msx2 mutants: defects in hair cycling and hair shaft differentiation
Published in Development (Cambridge) (01-01-2003)“…Msx2 -deficient mice exhibit progressive hair loss, starting at P14 and followed by successive cycles of wavelike regrowth and loss. During the hair cycle,…”
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EctopicMsx2Overexpression Inhibits andMsx2Antisense Stimulates Calvarial Osteoblast Differentiation
Published in Developmental biology (01-05-1999)“…Msx2is believed to play a role in regulating bone development, particularly in sutures of cranial bone. In this study we investigated the effects of…”
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Analyses of regenerative wave patterns in adult hair follicle populations reveal macro-environmental regulation of stem cell activity
Published in The International journal of developmental biology (2009)“…The control of hair growth in the adult mammalian coat is a fascinating topic which has just begun to be explored with molecular genetic tools. Complex hair…”
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Direct Induction of DNA Hypermethylation in Sea Urchin Embryos by Microinjection of 5-Methyl dCTP Stimulates Early Histone Gene Expression and Leads to Developmental Arrest
Published in Developmental biology (1993)“…The role of DNA methylation in gene inactivation has been studied extensively in vertebrates but it is not clear whether it serves similar functions in other…”
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Adaptation: A developmental biologist in the Antarctic
Published in Genesis (New York, N.Y. : 2000) (01-07-2005)Get full text
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The Molecular Basis of Boston-Type Craniosynostosis: The Pro148→His Mutation in the N-Terminal Arm of the MSX2 Homeodomain Stabilizes DNA Binding without Altering Nucleotide Sequence Preferences
Published in Human molecular genetics (01-12-1996)“…Craniosynostosis, Boston type is an autosomal dominant disorder that results in the premature fusion of cal-varial bones and ensuing abnormalities in skull…”
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A mutation in the homeodomain of the human MSX2 gene in a family affected with autosomal dominant craniosynostosis
Published in Cell (05-11-1993)“…Craniosynostosis, the premature fusion of calvarial sutures, is a common developmental anomaly that causes abnormal skull shape. The locus for one autosomal…”
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Ectopic Msx2 overexpression inhibits and Msx2 antisense stimulates calvarial osteoblast differentiation
Published in Developmental biology (15-05-1999)“…Msx2 is believed to play a role in regulating bone development, particularly in sutures of cranial bone. In this study we investigated the effects of…”
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Disruption of primary mesenchyme cell patterning by misregulated ectodermal expression of SpMsx in sea urchin embryos
Published in Developmental biology (15-09-1998)“…The patterning of the mesoderm of the sea urchin embryo is a classical paradigm of epithelial mesenchymal interactions in organogenesis, yet little is known of…”
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Disruption of Primary Mesenchyme Cell Patterning by Misregulated Ectodermal Expression ofSpMsxin Sea Urchin Embryos
Published in Developmental biology (15-09-1998)“…The patterning of the mesoderm of the sea urchin embryo is a classical paradigm of epithelial mesenchymal interactions in organogenesis, yet little is known of…”
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SpHbox7, a new Abd‐B class homeobox gene from the sea urchin Strongylocentrotus purpuratus: Insights into the evolution of hox gene expression and function
Published in Developmental dynamics (01-12-1996)“…Hox genes, by virtue of their key functions in axial patterning, have long been thought to be pivotal players in the evolution of developmental mechanisms…”
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Genomic structure, chromosomal location, and evolution of the mouse Hox 8 gene
Published in Genomics (San Diego, Calif.) (01-04-1993)“…We isolated genomic clones containing the mouse Hox 8 gene, a member of the msh gene family. We show that Hox 8 comprises two exons of approximately 600 and…”
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A POU gene required for early cleavage and protein accumulation in the sea urchin embryo
Published in Development (Cambridge) (01-07-1994)“…SpOct is a POU gene expressed during oogenesis and early embryogenesis of the sea urchin, Strongylocentrotus purpuratus. In the first use of antisense…”
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Promoter analysis meets pattern formation: transcriptional regulatory genes in sea urchin embryogenesis
Published in Current opinion in genetics & development (1994)“…Analyses of spatial and temporal gene control mechanisms in the sea urchin embryo have identified several important trans-regulatory factors, including some…”
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Function of the Msx2 gene in the morphogenesis of the skull
Published in Annals of the New York Academy of Sciences (01-06-1996)Get more information
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An octamer element is required for the expression of the alpha H2B histone gene during the early development of the sea urchin
Published in Developmental biology (01-04-1992)“…Early (alpha) histone genes are one of several histone gene families in the sea urchin genome. They are expressed at high levels in blastula-stage embryos and…”
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Orphons: dispersed genetic elements derived from tandem repetitive genes of eucaryotes
Published in Cell (01-03-1981)“…We have discovered in animal cells a novel class of dispersed, solitary genetic elements derived from tandem multigene families. We refer to such displaced…”
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Miz1, a novel zinc finger transcription factor that interacts with Msx2 and enhances its affinity for DNA
Published in Mechanisms of development (01-07-1997)“…Msx2 is a homeobox gene with a regulatory role in inductive tissue interactions, including those that pattern the skull. We demonstrated previously that…”
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SpOct, a Gene Encoding the Major Octamer-Binding Protein in Sea Urchin Embryos: Expression Profile, Evolutionary Relationships, and DNA Binding of Expressed Protein
Published in Developmental biology (01-08-1993)“…We have characterized a sea urchin gene, SpOct, that encodes a 78-kDa POU-domain protein related to mammalian Oct-1 and Oct-2. The SpOct protein binds octamer…”
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