Search Results - "Maxey, C."

Membrane proteins and membrane proteomics by Tan, Sandra, Tan, Hwee Tong, Chung, Maxey C.M

“…Biological membranes form an essential barrier between living cells and their external environments, as well as serve to compartmentalize intracellular…”
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Serum autoantibodies as biomarkers for early cancer detection by Tan, Hwee Tong, Low, Jiayi, Lim, Seng Gee, Chung, Maxey C.M

“…Autoantibodies against autologus tumor-associated antigens have been detected in the asymptomatic stage of cancer and can thus serve as biomarkers for early…”
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Identification of Key Players for Colorectal Cancer Metastasis by iTRAQ Quantitative Proteomics Profiling of Isogenic SW480 and SW620 Cell Lines by Ghosh, Dipanjana, Yu, Han, Tan, Xing Fei, Lim, Teck Kwang, Zubaidah, Ramdzan M, Tan, Hwee Tong, Chung, Maxey C. M, Lin, Qingsong

“…This study compared the whole cell proteome profiles of two isogenic colorectal cancer (CRC) cell lines (primary SW480 cell line and its lymph node metastatic…”
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EP01.19: First trimester screening and prevention of pre‐eclampsia: a patient perspective by Silang, K.A., Pastuck, M., Tomforh‐Madsen, L., Maxey, C., Johnson, J.M.

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A simple biomarker scoring matrix for early gastric cancer detection by Wu, Wei, Yong, Wen Wei, Chung, Maxey C. M.

“…Gastric cancer (GC) is a major cause of death in many parts of the world. While 90% of early GC is curable by resection, only about 5% of patients diagnosed in…”
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Mining the Gastric Cancer Secretome: Identification of GRN as a Potential Diagnostic Marker for Early Gastric Cancer by Loei, Hendrick, Tan, Hwee Tong, Lim, Teck Kwang, Lim, Kiat Hon, So, Jimmy Bok-Yan, Yeoh, Khay Guan, Chung, Maxey C. M

“…Gastric cancer is the second leading cause of cancer deaths worldwide, and currently, there are no clinically relevant biomarkers for gastric cancer diagnosis…”
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Cancer proteomics by Tan, Hwee Tong, Lee, Yie Hou, Chung, Maxey C.M.

“…Cancer presents high mortality and morbidity globally, largely due to its complex and heterogenous nature, and lack of biomarkers for early diagnosis. A…”
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Subcellular fractionation methods and strategies for proteomics by Lee, Yie Hou, Tan, Hwee Tong, Chung, Maxey C.M

“…Developments in subcellular fractionation strategies have provided the means to profile and analyze the protein composition of organelles and cellular…”
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Aging: Mechanisms, Measures, and Interventions by Chung, Maxey C. M., Kennedy, Brian K.

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Identification and Functional Validation of Caldesmon as a Potential Gastric Cancer Metastasis-associated Protein by Hou, Qian, Tan, Hwee Tong, Lim, Kiat Hon, Lim, Teck Kwang, Khoo, Avery, Tan, Iain B.H, Yeoh, Khay Guan, Chung, Maxey C. M

“…In this study, we aim to identify biomarkers for gastric cancer metastasis using a quantitative proteomics approach. The proteins extracted from a panel of 4…”
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iTRAQ analysis of colorectal cancer cell lines suggests Drebrin (DBN1) is overexpressed during liver metastasis by Lin, Qifeng, Tan, Hwee Tong, Lim, Teck Kwang, Khoo, Avery, Lim, Kiat Hon, Chung, Maxey C. M.

“…Colorectal cancer is currently the third in cancer incidence worldwide and the fourth most common cause of cancer deaths. Mortality in colorectal cancer is…”
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Anti-cancer properties of anthraquinones from rhubarb by Huang, Qing, Lu, Guodong, Shen, Han-Ming, Chung, Maxey C.M., Ong, Choon Nam

“…Rhubarb has been used as a traditional Chinese medicine since ancient times and today it is still present in various herbal preparations. In this review the…”
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Integrative Toxicoproteomics Implicates Impaired Mitochondrial Glutathione Import as an Off-Target Effect of Troglitazone by Lee, Yie Hou, Goh, Wilson Wen Bin, Ng, Choon Keow, Raida, Manfred, Wong, Limsoon, Lin, Qingsong, Boelsterli, Urs A, Chung, Maxey C. M

“…Troglitazone, a first-generation thiazolidinedione of antihyperglycaemic properties, was withdrawn from the market due to unacceptable idiosyncratic…”
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11th Asia Oceania Human Proteome Organization Congress Report by Grey, Angus C., Lin, Qingsong, Low, Teck Yew, Wu, Wei, Haynes, Paul A., Chung, Maxey C.M., Chen, Yu-Ju, Cordwell, Stuart J., Ishihama, Yasushi, Xu, Ping, Hoffmann, Peter, Kwon, Ho Jeong, Poon, Terence C.W.

“…As the first in-person Asia Oceania Human Proteomics Organization (AOHUPO) congress since 2018, the 11th AOHUPO congress was an opportune time for the research…”
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Analysis of colorectal cancer glyco-secretome identifies laminin β-1 (LAMB1) as a potential serological biomarker for colorectal cancer by Lin, Qifeng, Lim, Hannah S.R., Lin, Hui Ling, Tan, Hwee Tong, Lim, Teck Kwang, Cheong, Wai Kit, Cheah, Peh Yean, Tang, Choong Leong, Chow, Pierce K. H., Chung, Maxey C. M.

“…The high mortality rate in colorectal cancer is mostly ascribed to metastasis, but the only clinical biomarker available for disease monitoring and prognosis…”
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A proteomic analysis of thioacetamide-induced hepatotoxicity and cirrhosis in rat livers by Low, Teck Yew, Leow, Chon Kar, Salto-Tellez, Manuel, Chung, Maxey C. M.

“…Thioacetamide (TAA) administration is an established technique for generating rat models of liver fibrosis and cirrhosis. Oxidative stress is believed to be…”
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Proteomic Analysis of the Oil Palm Fruit Mesocarp Reveals Elevated Oxidative Phosphorylation Activity is Critical for Increased Storage Oil Production by Loei, Hendrick, Lim, Justin, Tan, Melvin, Lim, Teck Kwang, Lin, Qing Song, Chew, Fook Tim, Kulaveerasingam, Harikrishna, Chung, Maxey C. M

“…Palm oil is a highly versatile commodity with wide applications in the food, cosmetics, and biofuel industries. Storage oil in the oil palm mesocarp can make…”
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Proteomic Analysis of Colorectal Cancer Metastasis: Stathmin-1 Revealed as a Player in Cancer Cell Migration and Prognostic Marker by Tan, Hwee Tong, Wu, Wei, Ng, Yi Zhen, Zhang, Xuxiao, Yan, Benedict, Ong, Chee Wee, Tan, Sandra, Salto-Tellez, Manuel, Hooi, Shing Chuan, Chung, Maxey C. M

“…Metastasis accounts largely for the high mortality rate of colorectal cancer (CRC) patients. In this study, we performed comparative proteome analysis of…”
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Heart extracellular matrix supports cardiomyocyte differentiation of mouse embryonic stem cells by Higuchi, Sayaka, Lin, Qingsong, Wang, Jigang, Lim, Teck Kwang, Joshi, Shashikant B., Anand, Ganesh Srinivasan, Chung, Maxey C.M., Sheetz, Michael P., Fujita, Hideaki

“…We have evaluated the effect of heart extracellular matrix (ECM) on the cardiomyocyte differentiation of mouse embryonic stem cells (ES cells) using…”
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Next Generation Proteomics for Clinical Biomarker Detection Using SWATH-MS by Lin, Qifeng, Tan, Hwee Tong, Chung, Maxey C M

“…The technology of "sequential windowed acquisition of all theoretical fragment ion spectra," known as SWATH-MS, is rapidly gaining popularity as a next…”
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