Search Results - "Mavropoulos, Spyros A."

Progress in Clinical Gene Therapy for Cardiac Disorders by Romeo, Francisco J., Mavropoulos, Spyros A., Ishikawa, Kiyotake

“…Despite significant advances in novel treatments and approaches, cardiovascular disease remains the leading cause of death globally. Gene therapy is a…”
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Device-Based Approaches Targeting Cardioprotection in Myocardial Infarction: The Expanding Armamentarium of Innovative Strategies by Romeo, Francisco José, Mazurek, Renata, Sakata, Tomoki, Mavropoulos, Spyros A, Ishikawa, Kiyotake

“…Coronary reperfusion therapy has played a pivotal role for reducing mortality and heart failure after acute myocardial infarction. Although several adjunctive…”
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Nicotinic acetylcholine receptor-mediated protection of the rat heart exposed to ischemia reperfusion by Mavropoulos, Spyros A, Khan, Nayaab S, Levy, Asaph C J, Faliks, Bradley T, Sison, Cristina P, Pavlov, Valentin A, Zhang, Youhua, Ojamaa, Kaie

“…Reperfusion injury following acute myocardial infarction is associated with significant morbidity. Activation of neuronal or non-neuronal cholinergic pathways…”
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Left Ventricular Pressure Volume Assessment Using Carotid Artery Access in the Rat by Mavropoulos, Spyros A, Ishikawa, Kiyotake

“…Left ventricular (LV) catheterization with either a pressure catheter or pressure-volume catheter provides a means to measure cardiac function, an important…”
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Swine Model of Coronary Artery Dissection by Leonard, Kyra, Mavropoulos, Spyros A, Mazurek, Renata, Ishikawa, Kiyotake

“…Coronary artery dissection (CAD) is the intimal tearing of the coronary arterial wall and can be iatrogenic, spontaneous, or traumatic in origin. CAD is a rare…”
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Cardiac Gene Delivery in Large Animal Models: Antegrade Techniques by Mavropoulos, Spyros A, Yamada, Kelly P, Sakata, Tomoki, Ishikawa, Kiyotake

“…Percutaneous antegrade coronary injection is among the least invasive cardiac selective gene delivery methods. However, the transduction efficiency of a simple…”
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Reduction of left ventricular diastolic pressure as a key regulator of infarct coronary flow under mechanical left ventricular support by Sakata, Tomoki, Mavropoulos, Spyros A., Mazurek, Renata, Romeo, Francisco J., Ravichandran, Anjali J., Marx, Jonas M., Kariya, Taro, Ishikawa, Kiyotake

“…Restoring ischaemic myocardial tissue perfusion is crucial for minimizing infarct size. Acute mechanical left ventricular (LV) support has been suggested to…”
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Impact of ischemia on left atrial remodeling and dysfunction in swine models of mitral regurgitation by Sakata, Tomoki, Mazurek, Renata, Mavropoulos, Spyros A, Romeo, Francisco J, Ravichandran, Anjali J, Watanabe, Shin, Kariya, Taro, Ishikawa, Kiyotake

“…Left atrial (LA) dysfunction is one of the predictive factors of worse outcomes after mitral valve surgery for mitral regurgitation (MR). We aimed to…”
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Correction: Progress in Clinical Gene Therapy for Cardiac Disorders by Romeo, Francisco J., Mavropoulos, Spyros A., Ishikawa, Kiyotake

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Assessing the Effect of Cardiac Gene Therapy Using Catheter-Based Pressure-Volume Measurement in Large Animals by Sakata, Tomoki, Mazurek, Renata, Mavropoulos, Spyros A, Romeo, Francisco J, Ravichandran, Anjali J, Ishikawa, Kiyotake

“…Gene therapy for heart failure targets various pathways that modulate cardiac function. Its detailed evaluation is crucial for proving the efficacy of cardiac…”
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Negative Impact of Acute Reloading after Mechanical Left Ventricular Unloading by Mazurek, Renata, Kariya, Taro, Sakata, Tomoki, Mavropoulos, Spyros A., Ravichandran, Anjali J., Romeo, Francisco J., Yamada, Kelly P., Ishikawa, Kiyotake

“…Mechanical LV unloading for acute myocardial infarction (MI) is a promising supportive therapy to reperfusion. However, no data is available on exit strategy…”
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Inhibition of endothelial-to-mesenchymal transition in a large animal preclinical arteriovenous fistula model leads to improved remodelling and reduced stenosis by Xu, Yang, Korayem, Adam, Cruz-Solbes, Ana S, Chandel, Nirupama, Sakata, Tomoki, Mazurek, Renata, Mavropoulos, Spyros A, Kariya, Taro, Aikawa, Tadao, Yamada, Kelly P, D'Escamard, Valentina, V'Gangula, Bhargavi, Baker, Andrew H, Ma, Lijiang, Björkegren, Johan L M, Fuster, Valentin, Boehm, Manfred, Fish, Kenneth M, Tadros, Rami, Ishikawa, Kiyotake, Kovacic, Jason C

“…Abstract Aims Vein grafts are used for many indications, including bypass graft surgery and arteriovenous fistula (AVF) formation. However, patency following…”
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Abstract P2034: Minimally-invasive Porcine Model For The Study Of Cardiac Remodeling In Type 4 Cardiorenal Syndrome by Mavropoulos, Spyros A, Sakata, Tomoki, Mazurek, Renata, Ravichandran, Anjali, Marx, Jonas, Raisinghani, Nikhil, Sahoo, Susmita, Ishikawa, Kiyotake

“…Abstract only Background: CKD is on the rise, and over half of patients die due to cardiac causes, usually HF. They present with HF not only due to volume…”
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Nicotinic Acetylcholine Receptor-Mediated Protection of the Ischemic/Reperfused Heart by Mavropoulos, Spyros A

“…Reperfusion injury following acute myocardial infarction is associated with significant morbidity, and activation of nicotinic acetylcholine receptors (nAChR)…”
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Inhibition of endothelial to mesenchymal transition in a large animal preclinical arterio-venous fistula model leads to improved remodeling and reduced stenosis by Xu, Yang, Korayem, Adam, Cruz-Solbes, Ana S, Chandel, Nirupama, Sakata, Tomoki, Mazurek, Renata, Mavropoulos, Spyros A, Kariya, Taro, Aikawa, Tadao, Yamada, Kelly P, D'Escamard, Valentina, V'Gangula, Bhargavi, Baker, Andrew H, Ma, Lijiang, Björkegren, Johan L M, Fuster, Valentin, Boehm, Manfred, Fish, Kenneth M, Tadros, Rami, Ishikawa, Kiyotake, Kovacic, Jason C

“…Vein grafts are used for many indications, including bypass graft surgery and arterio-venous fistula (AVF) formation. However, patency following vein grafting…”
Get full text