Search Results - "Mavromatis, Blanche"

MammaPrint guides treatment decisions in breast Cancer: results of the IMPACt trial by Soliman, Hatem, Shah, Varsha, Srkalovic, Gordan, Mahtani, Reshma, Levine, Ellis, Mavromatis, Blanche, Srinivasiah, Jayanthi, Kassar, Mohamad, Gabordi, Robert, Qamar, Rubina, Untch, Sarah, Kling, Heather M, Treece, Tina, Audeh, William

“…Increased usage of genomic risk assessment assays suggests increased reliance on data provided by these assays to guide therapy decisions. The current study…”
Get full text

Breakthrough SARS-CoV-2 infections among patients with cancer following two and three doses of COVID-19 mRNA vaccines: a retrospective observational study from the COVID-19 and Cancer Consortium by Choueiri, Toni K., Labaki, Chris, Bakouny, Ziad, Hsu, Chih-Yuan, Schmidt, Andrew L., de Lima Lopes, Gilberto, Hwang, Clara, Singh, Sunny R.K., Jani, Chinmay, Weissmann, Lisa B., Griffiths, Elizabeth A., Halabi, Susan, Wu, Ulysses, Berg, Stephanie, O'Connor, Timothy E., Wise-Draper, Trisha M., Panagiotou, Orestis A., Klein, Elizabeth J., Joshi, Monika, Yared, Fares, Dutra, Miriam Santos, Gatson, Na Tosha N., Blau, Sibel, Singh, Harpreet, Nanchal, Rahul, McKay, Rana R., Nonato, Taylor K., Quinn, Ryann, Rubinstein, Samuel M., Puc, Matthew, Mavromatis, Blanche H., Vikas, Praveen, Faller, Bryan, Zaren, Howard A., Del Prete, Salvatore, Russell, Karen, Reuben, Daniel Y., Accordino, Melissa K., Singh, Harpreet, Friese, Christopher R., Mishra, Sanjay, Rivera, Donna R., Shyr, Yu, Farmakiotis, Dimitrios, Warner, Jeremy L.

“…Breakthrough SARS-CoV-2 infections following vaccination against COVID-19 are of international concern. Patients with cancer have been observed to have worse…”
Get full text

Monoclonal Antibody Therapy of Chronic Lymphocytic Leukemia by MAVROMATIS, Blanche, CHESON, Bruce D

“…Chemotherapeutic approaches during the last decade have failed to result in major advances in the outcome of patients with chronic lymphocytic leukemia (CLL)…”
Get full text

Preferential killing of PTEN-null myelomas by PI3K inhibitors through Akt pathway by JIE ZHANG, YONG CHOI, MAVROMATIS, Blanche, LICHTENSTEIN, Alan, WEIQUN LI

“…We recently reported that internal deletion of PTEN tumor suppressor gene in OPM2 and Delta47 myeloma lines led to high Akt activation. Re-expression of PTEN…”
Get full text

Novel therapies for chronic lymphocytic leukemia by Mavromatis, Blanche H, Cheson, Bruce D

“…New therapies for chronic lymphocytic leukemia (CLL) are moving away from non-specific cytotoxic to more targeted approaches. The monoclonal antibody…”
Get full text

Pre- and post-treatment evaluation of non-Hodgkin's lymphoma by Mavromatis, Blanche H., Cheson, Bruce D.

“…Once the diagnosis of a non-Hodgkin's lymphoma (NHL) has been established three critical steps in patient management must follow. The first is the…”
Get full text

Abstract OT2-07-01: The FLEX real-world data platform explores new gene expression profiles and investigator-initiated protocols in early-stage breast cancer by Ma, Cynthia X., Maganini, Robert, Whitworth, Pat, Crozier, Jennifer A., O'Shaughnessy, Joyce, Diab, Sami, Lesnikoski, Beth-Ann, Lee, June, D'Abreo, Nina, Mavromatis, Blanche H., Kelemen, Pond, Pronin, Darina, Abebe, Hiwot, Bolner, Michelle L., Finn, Christine, Blumencranz, Lisa, Audeh, William

“…Background: Genomic signatures provide prognostic information such as tumor metastatic potential, outperforming information gained from clinicopathologic…”
Get full text

Abstract P2-14-11: Treatment recommendations in ER+ patients ≤ 50 years: Comparison of the 21-gene assay and 70-gene signature in the PROMIS study by Tsai, Michaela, Soliman, Hatem, Lo, Shelly, Qamar, Rubina, Budway, Raye, Levine, Ellis, Whitworth, Pat, Mavromatis, Blanche, Zon, Robin, Untch, Sarah, Blumencranz, Lisa, McKelley, Joseph, Audeh, William

“…Background: The PROMIS trial (NCT01617954) previously evaluated how a definitive result from the MammaPrint 70-gene signature (70-GS) can impact treatment…”
Get full text

Abstract LB-320: The FLEX real world data platform explores new gene expression profiles and investigator-initiated protocols in early stage breast cancer by Crozier, Jennifer, Brufsky, Adam, Grady, Ian, Diab, Sami, Mavromatis, Blanche, D'Abreo, Nina, Dul, Carrie, Rahman, Rakhshanda Layeequr, Untch, Sarah, Yoder, Erin, Kling, Heather M., Truitt, Amy M., Audeh, William, van der Baan, Bastiaan

“…Background: Genomic expression profiles have enabled the classification of breast cancers into molecular subtypes and provide prognostic information about the…”
Get full text

The FLEX real-world data platform explores new gene expression profiles and investigator-initiated protocols in early stage breast cancer by D'Abreo, Nina, Crozier, Jennifer A., Brufsky, Adam, Grady, Ian, Diab, Sami, Mavromatis, Blanche H., Dul, Carrie L., Layeequr Rahman, Rakhshanda, Lee, Laura A., Gadi, Vijayakrishna K., Untch, Sarah, Yoder, Erin, Kling, Heather M., Truitt, Amy, Audeh, William

“…Abstract only TPS7088 Background: Genomic expression profiles have enabled the classification of breast cancers into molecular sub-types and provide prognostic…”
Get full text

Code status and outcomes in patients with cancer and COVID-19: A COVID-19 and cancer consortium (CCC19) registry analysis by Loggers, Elizabeth Trice, Wulff-Burchfield, Elizabeth Marie, Subbiah, Ishwaria Mohan, Khaki, Ali Raza, Egan, Pamela, Farmakiotis, Dimitrios, Phull, Hardeep, Nakasone, Elizabeth, Labaki, Chris, Yu, Peter Paul, Joshi, Monika, Griffiths, Elizabeth A., Wise-Draper, Trisha Michel, Jani, Chinmay, Thakkar, Astha, Puc, Matthew, Hwang, Clara, Mavromatis, Blanche H., Shah, Dimpy P, Warner, Jeremy Lyle

“…Abstract only 12035 Background: In-hospital mortality among patients with cancer (pts) and COVID-19 infection is high. The frequency of, and factors associated…”
Get full text

Association of 70-Gene Signature Assay Findings With Physicians' Treatment Guidance for Patients With Early Breast Cancer Classified as Intermediate Risk by the 21-Gene Assay by Tsai, Michaela, Lo, Shelly, Audeh, William, Qamar, Rubina, Budway, Raye, Levine, Ellis, Whitworth, Pat, Mavromatis, Blanche, Zon, Robin, Oldham, Dwight, Untch, Sarah, Treece, Tina, Blumencranz, Lisa, Soliman, Hatem

“…Among patients who undergo the 21-gene assay (21-GA), 39% to 67% receive an intermediate risk result and may receive ambiguous treatment guidance. The 70-gene…”
Get more information

The impact of cancer metastases on COVID‐19 outcomes: A COVID‐19 and Cancer Consortium registry‐based retrospective cohort study by Castellano, Cecilia A., Sun, Tianyi, Ravindranathan, Deepak, Hwang, Clara, Balanchivadze, Nino, Singh, Sunny R. K., Griffiths, Elizabeth A., Puzanov, Igor, Ruiz‐Garcia, Erika, Vilar‐Compte, Diana, Cárdenas‐Delgado, Ana I., McKay, Rana R., Nonato, Taylor K., Ajmera, Archana, Yu, Peter P., Nadkarni, Rajani, O’Connor, Timothy E., Berg, Stephanie, Ma, Kim, Farmakiotis, Dimitrios, Vieira, Kendra, Arvanitis, Panos, Saliby, Renee M., Labaki, Chris, El Zarif, Talal, Wise‐Draper, Trisha M., Zamulko, Olga, Li, Ningjing, Bodin, Brianne E., Accordino, Melissa K., Ingham, Matthew, Joshi, Monika, Polimera, Hyma V., Fecher, Leslie A., Friese, Christopher R., Yoon, James J., Mavromatis, Blanche H., Brown, Jacqueline T., Russell, Karen, Nanchal, Rahul, Singh, Harpreet, Tachiki, Lisa, Moria, Feras A., Nagaraj, Gayathri, Cortez, Kimberly, Abbasi, Saqib H., Wulff‐Burchfield, Elizabeth M., Puc, Matthew, Weissmann, Lisa B., Bhatt, Padmanabh S., Mariano, Melissa G., Mishra, Sanjay, Halabi, Susan, Beeghly, Alicia, Warner, Jeremy L., French, Benjamin, Bilen, Mehmet A.

“…Background COVID‐19 can have a particularly detrimental effect on patients with cancer, but no studies to date have examined if the presence, or site, of…”
Get full text

Brief Report: Impact of Anti-Cancer Treatments on Outcomes of COVID-19 in Patients With Thoracic Cancers: A CCC19 Registry Analysis by Kulkarni, Amit A., Hennessy, Cassandra, Wilson, Grace, Ramesh, Vidhyalakshmi, Hwang, Clara, Awosika, Joy, Bakouny, Ziad, Khan, Hina, Vilar-Compte, Diana, McKay, Rana, Jani, Chinmay, Weissmann, Lisa, Griffiths, Elizabeth, Batist, Gerald, Bouganim, Nathaniel, Mavromatis, Blanche, Bashir, Babar, Nguyen, Ryan H., Riess, Jonathan W., Puc, Matthew, Kasi, Anup, Berg, Stephanie, Castillo, Dan Ran, Hayes-Lattin, Brandon, Hosmer, Wylie, Flora, Daniel, Mishra, Sanjay, French, Benjamin, Warner, Jeremy L., Lopes, Gilberto, Peters, Solange, Florez, Narjust

“…•Patients with thoracic cancers and COVID-19 have high mortality and morbidity.•Systematic data evaluating the impact of recent anti-cancer therapies on…”
Get full text

Effect of metabolic syndrome on risk of recurrence and immune pathways in invasive lobular carcinoma disparately compared to ductal by Robinson, Patricia A., Treece, Tina, Osipo, Clodia, Qamar, Rubina, Zon, Robin, Levine, Ellis Glenn, Budway, Raye, Mavromatis, Blanche H., Untch, Sarah, Bernards, Rene, Audeh, M. William, Soliman, Hatem Hussein

“…Abstract only…”
Get full text

Abstract PO4-02-03: Distribution of MammaPrint, BluePrint, and Response Predictive Subtypes based on ImPrint and Reprint in ER+/HER2- Invasive Lobular Carcinoma – A FLEX sub study by Mukhtar, Rita, Yau, Christina, Wolf, Denise, Brufsky, Adam, Linden, Hannah, Hunter, Natasha, Mahtani, Reshma, Sivapiragasam, Abirami, Feinstein, Trevor, Yan, Fengting, Grady, Ian, McAuliffe, Priscilla, Tsai, Michaela, O'Shaughnessy, Joyce, Mavromatis, Blanche, Davis, Sasha, Haan, Josien, Audeh, William, Samraj, Lavanya

“…Background: Invasive lobular carcinoma (ILC), the second most common histologic subtype of breast cancer, is increasingly recognized as a distinct tumor type…”
Get full text

Abstract PD9-08: ImPrint immune signature in 10,000 early-stage breast cancer patients from the real-world FLEX database by Brufsky, Adam M., Kuilman, Midas, Mukhtar, Rita, Wolf, Denise M., Yau, Christina, O’Shaughnessy, Joyce, Graham, Cathy, Gadi, Vijayakrishna K., Whitworth, Pat, Hindenburg, Alexander, Grady, Ian, Srkalovic, Gordon, Hoskins, Kent, Dhakal, Ajay, Ma, Cynthia, Hunter, Natasha, Crozier, Jennifer, Mavromatis, Blanche, Mittempergher, Lorenza, Finn, Christine, Modh, Shraddha, Yoder, Erin B., Dauer, Patricia, Menicucci, Andrea, van der Baan, Bas, Audeh, William, Esserman, Laura J.

“…BACKGROUND: Immune checkpoint inhibitors in combination with chemotherapy have demonstrated an improvement of pathologic complete response (pCR) in patients…”
Get full text

Sjögren-like Disease and Silicone Implants A Greek Experience by Mavromatis, Blanche H, Tzioufas, Athanasios G, Moutsopoulos, Haralampos M

Get full text

Efficacy of solubilized vemurafenib administered via nasogastric tube by Khimani, Farhad, Hoban, Christina, Williams, Vicky, Mavromatis, Blanche, Auber, Miklos L, Abraham, Jame, Higa, Gerald M

“…Until only a few years ago, there was only one truly effective therapy for patients with metastatic melanoma. While long-term remission could be achieved in…”
Get more information

Four Cycles of Standard Bortezomib and Dexamethasone Produce Significant Overall Response Rates In Patients with Relapsed/Refractory Multiple Myeloma by Trivedi, Harsha, Mavromatis, Blanche, Chamarthy, Usha Sree, Al-Janadi, Anas, Gilreath, Vicki, Srkalovic, Gordan

“…Abstract 5046 Bortezomib (B) is a reversible proteasome inhibitor approved by FDA for relapsed/refractory multiple myeloma (MM) patients (pts) in second and…”
Get full text