Search Results - "Mavromatakis, Yannis E"
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Foxa1 and Foxa2 regulate multiple phases of midbrain dopaminergic neuron development in a dosage-dependent manner
Published in Development (Cambridge) (01-08-2007)“…The role of transcription factors in regulating the development of midbrain dopaminergic (mDA) neurons is intensively studied owing to the involvement of these…”
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Journal Article -
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The mir-279/996 cluster represses receptor tyrosine kinase signaling to determine cell fates in the Drosophila eye
Published in Development (Cambridge) (01-04-2018)“…Photoreceptors in the crystalline eye are recruited by receptor tyrosine kinase (RTK)/Ras signaling mediated by Epidermal growth factor receptor (EGFR) and the…”
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Journal Article -
3
Foxa1 and Foxa2 function both upstream of and cooperatively with Lmx1a and Lmx1b in a feedforward loop promoting mesodiencephalic dopaminergic neuron development
Published in Developmental biology (15-09-2009)“…Mesodiencephalic dopaminergic neurons control voluntary movement and reward based behaviours. Their dysfunction can lead to neurological disorders, including…”
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Journal Article -
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Foxa1 and Foxa2 positively and negatively regulate Shh signalling to specify ventral midbrain progenitor identity
Published in Mechanisms of development (01-01-2011)“…Foxa2, a member of the Foxa family of forkhead/winged helix family of transcription factors, has previously been shown to be an upstream positive regulator of…”
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Journal Article -
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Role of the forkhead transcription factor Foxa2 in the development of the ventral mesencephalon : a study using conditional mouse mutants
Published 01-01-2006“…The developing mesencephalon consists of two distinct domains. The dorsal domain, the tectum, gives rise to the superior and inferior colliculi, which in the…”
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Dissertation