Search Results - "Mauriello, Clifford T"
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Peptide Inhibitor of Complement C1 (PIC1) Rapidly Inhibits Complement Activation after Intravascular Injection in Rats
Published in PloS one (21-07-2015)“…The complement system has been increasingly recognized to play a pivotal role in a variety of inflammatory and autoimmune diseases. Consequently, therapeutic…”
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Hyperglycemia Inhibits Complement-Mediated Immunological Control of S. aureus in a Rat Model of Peritonitis
Published in Journal of diabetes research (01-01-2014)“…Hyperglycemia from diabetes is associated with increased risk of infection from S. aureus and increased severity of illness. Previous work in our laboratory…”
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Association Between Updated Guideline-Based Palivizumab Administration and Hospitalizations for Respiratory Syncytial Virus Infections
Published in The Pediatric infectious disease journal (01-07-2016)“…BACKGROUND:Since its introduction, palivizumab has been used to prevent respiratory syncytial virus (RSV) infection in high-risk populations. Recommendations…”
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An 11-Year-Old Male with Refractory Osteomyelitis
Published in Case reports in pediatrics (01-01-2012)“…We present a case of empirical treatment failure for chronic osteomyelitis in a previously healthy 11-year-old male involving the distal phalanx of the right…”
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Glucose-based dialysis fluids inhibit innate defense against Staphylococcus aureus
Published in Molecular immunology (01-10-2015)“…•Glucose- based PD fluids inhibit complement- mediated opsonization of S. aureus.•Neutrophil recruitment and activation is inhibited in glucose based PD…”
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Complement inhibition significantly decreases red blood cell lysis in a rat model of acute intravascular hemolysis
Published in Transfusion (Philadelphia, Pa.) (01-11-2014)“…Background Prevention of acute hemolytic transfusion reactions is a worldwide concern. The objective of this study was to develop a simple rat model of…”
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A novel peptide inhibitor of classical and lectin complement activation including ABO incompatibility
Published in Molecular immunology (01-01-2013)“…► A 30 residue peptide is described that inhibits ABO incompatibility in vitro. ► This peptide can also inhibit in vivo complement activation in rats. ► This…”
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Clinical hypothermia temperatures increase complement activation and cell destruction via the classical pathway
Published in Journal of translational medicine (24-06-2014)“…Therapeutic hypothermia is a treatment modality that is increasingly used to improve clinical neurological outcomes for ischemia-reperfusion injury-mediated…”
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Inhibition of ABO incompatibility using a novel small peptide
Published in Immunobiology (1979) (01-11-2012)Get full text
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A 1-Year-Old With Mycobacterium tuberculosis Endocarditis With Mass Spectrometry Analysis of Cardiac Vegetation Composition
Published in Journal of the Pediatric Infectious Diseases Society (01-03-2016)“…In this study, we report the first case of Mycobacterium tuberculosis endocarditis in an immunocompetent child born in the United States. Mass spectrometry of…”
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