Search Results - "Mauri, Lucio"
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Differentiation of Generic Enoxaparins Marketed in the United States by Employing NMR and Multivariate Analysis
Published in Analytical chemistry (Washington) (18-08-2015)“…The U.S. Food and Drug Administration defines criteria for the equivalence of Enoxaparin with Lovenox, comprising the equivalence of physiochemical properties,…”
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Probing small network differences in sulfur-cured rubber compounds by combining nuclear magnetic resonance and swelling methods
Published in Journal of applied polymer science (15-11-2015)“…ABSTRACT We studied the network structure of elastomers based on polyisoprene, polybutadiene, and their blends in the narrow range of formulations compatible…”
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Combining NMR Spectroscopy and Chemometrics to Monitor Structural Features of Crude Hep-arin
Published in Molecules (Basel, Switzerland) (08-07-2017)“…Because of the complexity and global nature of the heparin supply chain, the control of heparin quality during manufacturing steps is essential to ensure the…”
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1D and 2D-HSQC NMR: Two Methods to Distinguish and Characterize Heparin From Different Animal and Tissue Sources
Published in Frontiers in medicine (27-06-2019)“…The US Food and Drug Administration has encouraged the reintroduction of bovine heparin drug product to the US market to mitigate the risks of heparin…”
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Qualification of HSQC methods for quantitative composition of heparin and low molecular weight heparins
Published in Journal of pharmaceutical and biomedical analysis (20-03-2017)“…•Robust heparin mono- and di-saccharide composition measurements are a key tests for ensuring drug quality.•NMR HSQC data enables quick and detailed heparin…”
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NMR spectroscopy and chemometric models to detect a specific non-porcine ruminant contaminant in pharmaceutical heparin
Published in Journal of pharmaceutical and biomedical analysis (30-05-2022)“…Heparin has been used successfully as a clinical antithrombotic for almost one century. Its isolation from animal sources (mostly porcine intestinal mucosa)…”
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Multivariate analysis applied to complex biological medicines
Published in Faraday discussions (15-08-2019)“…A biological medicine (or biologicals) is a term for a medicinal compound that is derived from a living organism. By their very nature, they are complex and…”
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Structural peculiarity and antithrombin binding region profile of mucosal bovine and porcine heparins
Published in Journal of pharmaceutical and biomedical analysis (25-01-2016)“…The major compositional differences between bovine mucosal heparin (BMH) and the currently employed porcine mucosal heparin (PMH) have been reported to…”
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Petrografia e termobarometria de granitoides diatexíticos portadores de anfibólio da Região de São José de Ubá e São João do Paraíso (RJ)
Published in Geologia USP. Série Científica (09-12-2020)“…Na região norte do Rio de Janeiro afloram rochas orto e paraderivadas neoproterozoicas de alto grau metamórfico, englobadas no Terreno Oriental da Faixa…”
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