Search Results - "Maurer, Meghan"

adaptor protein Dab2 sorts LDL receptors into coated pits independently of AP-2 and ARH by Maurer, Meghan E, Cooper, Jonathan A

“…Clathrin-mediated endocytosis requires cargo-specific adaptor proteins that recognize specific receptors and recruit them into coated pits. ARH [also called…”
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Preclinical characterization of MTX-101: a novel bispecific CD8 Treg modulator that restores CD8 Treg functions to suppress pathogenic T cells in autoimmune diseases by Gardell, Jennifer L., Maurer, Meghan E., Childs, Monica M., Pham, Minh N., Meengs, Brent, Julien, Susan H., Tan, Cong, Boster, Daniel R., Quach, Phoenicia, Therriault, Jon H., Hermansky, Gleda, Patton, Daniel T., Bowser, Justin, Chen, Alex, Morgan, Nadine N., Gilbertson, Emily A., Bogatzki, Lisa, Encarnacion, Kaelen, McMahan, Catherine J., Crane, Courtney A., Swiderek, Kristine M.

“…Introduction Regulatory CD8 T cells (CD8 Treg) are responsible for the selective killing of self-reactive and pathogenic CD4 T cells. In autoimmune disease,…”
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Endocytosis of megalin by visceral endoderm cells requires the Dab2 adaptor protein by Maurer, Meghan E, Cooper, Jonathan A

“…Rapid endocytosis of lipoprotein receptors involves NPxY signals contained in their cytoplasmic tails. Several proteins, including ARH and Dab2, can bind these…”
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Epigenetic downregulation of human disabled homolog 2 switches TGF-beta from a tumor suppressor to a tumor promoter by Hannigan, Adèle, Smith, Paul, Kalna, Gabriela, Lo Nigro, Cristiana, Orange, Clare, O'Brien, Darren I, Shah, Reshma, Syed, Nelofer, Spender, Lindsay C, Herrera, Blanca, Thurlow, Johanna K, Lattanzio, Laura, Monteverde, Martino, Maurer, Meghan E, Buffa, Francesca M, Mann, Jelena, Chu, David C K, West, Catharine M L, Patridge, Max, Oien, Karin A, Cooper, Jonathan A, Frame, Margaret C, Harris, Adrian L, Hiller, Louise, Nicholson, Linda J, Gasco, Milena, Crook, Tim, Inman, Gareth J

“…The cytokine TGF-beta acts as a tumor suppressor in normal epithelial cells and during the early stages of tumorigenesis. During malignant progression, cancer…”
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Sa1117: A NEWLY DISCOVERED REGULATORY CD8 T CELL NETWORK HAS THE POTENTIAL TO REGULATE AND ELIMINATE PATHOGENIC CD4 T CELLS IN AUTOIMMUNE MEDIATED DIGESTIVE DISEASE by Crane, Courtney, Bowser, Justin, Fasnacht, Rachael, Gardell, Jennifer, Julien, Susan, Maurer, Meghan, Templeton, Megan L., Therriault, Jon, Swiderek, Kristine M.

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A NEWLY DISCOVERED REGULATORY CD8 T CELL NETWORK HAS THE POTENTIAL TO REGULATE AND ELIMINATE PATHOGENIC CD4 T CELLS IN AUTOIMMUNE MEDIATED DISEASE OF THE GUT by Crane, Courtney, Bowser, Justin, Fasnacht, Rachael, Gardell, Jennifer, Maurer, Meghan, Julien, Susan, Templeton, Megan, Therriault, Jon Henry, Swiderek, Kristine

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A NOVEL BISPECIFIC CD8 TREG MODULATOR TARGETING CYTOLYTIC CD8 REGULATORY T CELLS REDUCES PATHOGENIC CD4 T CELLS AND INFLAMMATION IN TRANSLATIONAL MODELS OF INTESTINAL AUTOIMMUNE AND INFLAMMATORY DISEASE by Gardell, Jennifer, Boster, Daniel, Bowser, Justin, Crane, Courtney, Fasnacht, Rachael, Fitzpatrick, Kristin, Hermansky, Gleda, Julien, Susan, Maurer, Meghan, McMahan, Cathy, Meengs, Brent, Patton, Dan, Pham, Minh, Swiderek, Kristine

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A NEWLY DISCOVERED REGULATORY CD8 T CELL NETWORK HAS THE POTENTIAL TO REGULATE AND ELIMINATE PATHOGENIC CD4 T CELLS IN AUTOIMMUNE MEDIATED DISEASE OF THE GUT by Crane, Courtney, Bowser, Justin, Fasnacht, Rachael, Gardell, Jennifer, Maurer, Meghan, Julien, Susan, Templeton, Megan, Therriault, Jon Henry, Swiderek, Kristine

“…Abstract INTRODUCTION Several groups have described a subset of CD8 T cells with immunosuppressive characteristics in inflammatory disease settings. The…”
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Demonstration of regulatory CD8 T cell prevalence, phenotype, and functions in autoimmune patients treated with a tolerizing peptide vaccine by Maurer, Meghan, Bowser, Justin, Fasnacht, Rachael, Gardell, Jennifer L, Julien, Susan, Templeton, Megan, Therriault, Jon, Yang, Su J, Swiderek, Kristine, Crane, Courtney

“…Abstract INTRODUCTION Others have described a subset of CD8 T cells with immunosuppressive characteristics in inflammatory disease settings. CD8 Treg…”
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Bispecific CD8 Treg modulators regulate a novel regulatory CD8 T cell network and eliminate pathogenic CD4 T cells in live cell co-culture system by Gardell, Jennifer L, Crane, Courtney, Bowser, Justin, Fasnacht, Rachael, Julien, Susan, Maurer, Meghan E, Templeton, Megan, Therriault, Jon, Yang, Su Jung, Swiderek, Kristine M

“…Abstract INTRODUCTION Others have described a subset of CD8 T cells (CD8 Treg) with immunosuppressive characteristics in inflammatory disease settings. CD8…”
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A NOVEL BISPECIFIC CD8 TREG MODULATOR TARGETING CYTOLYTIC CD8 REGULATORY T CELLS REDUCES PATHOGENIC CD4 T CELLS AND INFLAMMATION IN TRANSLATIONAL MODELS OF INTESTINAL AUTOIMMUNE AND INFLAMMATORY DISEASE by Gardell, Jennifer, Boster, Daniel, Bowser, Justin, Crane, Courtney, Fasnacht, Rachael, Fitzpatrick, Kristin, Hermansky, Gleda, Julien, Susan, Maurer, Meghan, McMahan, Cathy, Meengs, Brent, Patton, Dan, Pham, Minh, Swiderek, Kristine

“…Abstract INTRODUCTION We have characterized a novel CD8 Treg network in autoimmune patient peripheral blood and tissues, in which a subset of cytolytic CD8…”
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Su1210 A NOVEL BISPECIFIC CD8 TREG MODULATOR TARGETING CYTOLYTIC CD8 REGULATORY T CELLS REDUCES PATHOGENIC CD4 T CELLS AND INFLAMMATION IN TRANSLATIONAL MODELS OF INTESTINAL AUTOIMMUNE AND INFLAMMATORY DISEASE by Gardell, Jennifer L., Boster, Daniel, Bowser, Justin, Crane, Courtney, Fasnacht, Rachael, Fitzpatrick, Kristin, Hermansky, Gleda, Julien, Susan, Maurer, Meghan, McMahan, Catherine J., Meengs, Brent, Patton, Daniel, Pham, Minh, Therriault, Jon, Swiderek, Kristine M.

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A KIR x CD8 targeting bispecific modulator enhances regulatory CD8 T cell functions, and reduces inflammation in models of autoimmune disease by Gardell, Jennifer L, Boster, Daniel, Bowser, Justin, Fasnacht, Rachael, Fitzpatrick, Kristin, Hermansky, Gleda, Julien, Susan, Maurer, Meghan, McMahan, Catherine, Meengs, Brent, Patton, Daniel, Pham, Minh, Therriault, Jon, Swiderek, Kristine M, Crane, Courtney

“…Abstract INTRODUCTION: We have characterized a subset of CD8 T cells (CD8 Treg) with immunosuppressive characteristics in inflammatory disease settings. CD8…”
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Su1736 MTX-101, A BISPECIFIC CD8 TREG MODULATOR, CORRECTS THE DYSFUNCTION IN CROHN'S PATIENT CD8 TREG TO RESTORE IMMUNE BALANCE by Gardell, Jennifer L., Bogatzki, Lisa, Boster, Daniel, Bowser, Justin, Childs, Monica, Fasnacht, Rachael, Hermansky, Gleda, Julien, Susan, Maurer, Meghan, Meengs, Brent, Morgan, Nadine, Patton, Daniel, Pham, Minh, Quach, Phoenicia, Tan, Cong, Therriault, Jon, McMahan, Catherine J., Crane, Courtney, Swiderek, Kristine M.

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A Study on the Effect of READ 180 on Reading Achievement and Growth Among Students with Disabilities by Maurer, Meghan M

“…This study investigated the Scholastic reading intervention program READ 180 and the impact its implementation had on reading achievement and growth in sixth…”
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Epigenetic downregulation of human disabled homolog 2 switches TGF-[Beta] from a tumor suppressor to a tumor promoter by Hannigan, Adèle, Smith, Paul, Kalna, Gabriela, Lo Nigro, Cristiana, Orange, Clare, O'Brien, Darren I, Shah, Reshma, Syed, Nelofer, Spender, Lindsay C, Herrera, Blanca, Thurlow, Johanna K, Lattanzio, Laura, Monteverde, Martino, Maurer, Meghan E, Buffa, Francesca M, Mann, Jelena, Chu, David C K, West, Catharine M L, Patridge, Max, Oien, Karin A, Cooper, Jonathan A, Frame, Margaret C, Harris, Adrian L, Hiller, Louise, Nicholson, Linda J, Gasco, Milena, Crook, Tim, Inman, Gareth J

“…The cytokine TGF-beta acts as a tumor suppressor in normal epithelial cells and during the early stages of tumorigenesis. During malignant progression, cancer…”
Get full text