Search Results - "Maurer, H. Rainer"

Prothymosin .alpha.: A Biologically Active Protein with Random Coil Conformation by Gast, Klaus, Damaschun, Hilde, Eckert, Klaus, Schulze-Forster, Kai, Maurer, H. Rainer, Mueller-Frohne, Marlies, Zirwer, Dietrich, Czarnecki, Jan, Damaschun, Gregor

“…Prothymosin is an acidic protein with an unusual amino acid composition. Though its exact function is not yet known, its high evolutionary conservation and…”
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Bromelain Reversibly Inhibits Invasive Properties of Glioma Cells by Tysnes, Berit B., Maurert, H. Rainer, Porwol, Torsten, Probst, Beatrice, Bjerkvig, Rolf, Hoover, Frank

“…Bromelain is an aqueous extract from pineapple stem that contains proteinases and exhibits pleiotropic therapeutic effects, i.e., antiedematous,…”
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Tributyrin-induced differentiation promotes apoptosis of LS 174T colon cancer cells in vitro by Schröder, Claudia P, Maurer, H Rainer

“…Tributyrin (glyceryl tributyrate, TB) is known to induce malignant cells to differentiate followed by arrest of cell growth and death via apoptosis. We…”
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Development and application of a simple assay to quantify cellular adducts of platinum complexes with DNA by KLOFT, C, EICKHOFF, C, SCHULZE-FORSTER, K, MAURER, H. R, SCHUNACK, W, JAEHDE, U

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Effects of differentiation inducers on cell phenotypes of cultured nontransformed and immortalized mammary epithelial cells: a comparative immunocytochemical analysis by Grünberg, E, Eckert, K, Karsten, U, Maurer, H R

“…We examined the effects of the differentiation-inducing agents 1, 25-dihydroxyvitamin D(3) (calcitriol), phorbol myristate acetate (PMA), the cytokine…”
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Antineoplastic activity and tolerability of a novel heterocyclic alkylphospholipid, D-20133 by STEKAR, J, HILGARD, P, VOEGELI, R, MAURER, H. R, ENGEL, J, KUTSCHER, B, NÖSSNER, G, SCHUMACHER, W

“…Octadecyl-[2-(N-methylpiperidinio)ethyl]-phosphate (OMPEP, D-20133), a heterocyclic analogue of hexadecylphosphocholine (MIL), has been synthesized in an…”
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Tributyrin induces growth inhibitory and differentiating effects on HT-29 colon cancer cells in vitro by Schröder, C, Eckert, K, Maurer, H R

“…Tributyrin (TB) is a prodrug of butyrate known to induce tumor cells to differentiate. We examined its effects on cell growth, viability, cellular morphology…”
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Bromelain proteases reduce human platelet aggregation in vitro, adhesion to bovine endothelial cells and thrombus formation in rat vessels in vivo by Metzig, C, Grabowska, E, Eckert, K, Rehse, K, Maurer, H R

“…The thiol protease, bromelain, an extract from pineapple stem, was suggested to have antithrombotic and anticoagulant activities in vivo. We studied the…”
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Isolation and characterization of two forms of an acidic bromelain stem proteinase by Harrach, T, Eckert, K, Maurer, H R, Machleidt, I, Machleidt, W, Nuck, R

“…Two forms of an acidic bromelain proteinase isolated from crude bromelain, an extract from pineapple stem, were found by a two-step FPLC purification…”
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Tributyrin enhances the cytotoxic activity of interleukin-2 interleukin-12 stimulated human natural killer cells against LS 174T colon cancer cells in vitro by SCHRÖDER, Claudia P, MAURER, H. Rainer

“…Tributyrin has been shown to be cytostatic to tumor cells by inducing differentiation and apoptosis. On the other hand, immunological NK cells can kill tumor…”
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Docetaxel treatment of HT-29 colon carcinoma cells reinforces the adhesion and immunocytotoxicity of peripheral blood lymphocytes in vitro by Grünberg, E, Eckert, K, Maurer, H R

“…In vitro effects of docetaxel on the human colon carcinoma cell line HT-29 were studied with respect to the expression of different adhesion and surface marker…”
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Expression and modulation of the Lewis x antigen (CD15) on the T cell line Molt-4 by Schulze-Forster, Kai, Maurer, H.Rainer

“…The T cell lines Molt-4 and H9 exhibited a characteristic distribution of the cell adhesion molecule Lewis x (CD15, lacto- N-fucopentanose III) showing an…”
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Evaluation of the MTT and SRB assays for testing LAK cell-mediated growth inhibition of various adherent and non-adherent tumor target cells by Garbin, F, Eckert, K, Maurer, H R

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A rapid and sensitive fluorometric screening assay using YO-PRO-1 to quantify tumour cell invasion through Matrigel by Gohla, A, Eckert, K, Maurer, H R

“…A new quantitative assay for the study of tumour cell invasion in vitro is described. Employing the novel fluorescent dye YO-PRO-1, cells that penetrate…”
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Induction of the c- myc but not the cH- ras promoter by platinum compounds by Eliopoulos, Aristides G., Kerr, David J., Maurer, H.Rainer, Hilgard, Peter, Spandidos, Demetrios A.

“…The recombinant plasmids p324, p330 and p323 carrying the aminoglycoside phosphotransferase ( aph) gene and 5′ flanking c- myc sequences linked to the reporter…”
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The thymus extract Thymex-L potentiates the retinoic acid-induced differentiation of the human myeloid leukemia cell line HL-60 by Schulze-Forster, Kai, Eckert, Klaus, Rainer Maurer, H.

“…The human promyelocytic cell line HL-60 can be differentiated with retinoic acid (RA) along the granulocytic pathway. Numerous studies have identified many…”
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Growth kinetics of L1210 leukemic cells exposed to different concentration courses of methotrexate in vitro by GIMMEL, S, MAURER, H. R

“…At present, pharmacokinetic aspects in existing in vitro assays for cytotoxic drug screening are considered only insufficiently. Using a new microperfusion…”
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Prothymosin α1 effects, in vitro, on the antitumor activity and cytokine production of blood monocytes from colorectal tumor patients by Garbin, Frank, Eckert, Klaus, Immenschuh, Peter, Kreuser, E.D., Maurer, H.Rainer

“…Recent animal studies demonstrate that prothymosin α1 (ProTα) enhances the antitumor response by stimulation of mononuclear phagocyte functions. The present…”
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Lymphokine-activated killer cells: determination of their tumor cytolytic capacity by a clonogenic microassay using agar capillaries by Echarti, C, Maurer, H R

“…A lymphokine activated killer (LAK) cell assay has been developed using a clonogenic microassay in agar-containing capillaries with KB tumor target cells. The…”
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Agar capillary clonogenic microassays for cellular immunocytotoxic activities in human leukaemia and lymphoma by Maurer, H R, Hassan, H T

“…Current concepts of immunotherapeutic approaches in leukemias and lymphomas using activated cytotoxic lymphocytes and macrophages are briefly reviewed…”
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