Search Results - "Maurel, Patrice"

Preparation of Neonatal Rat Schwann Cells and Embryonic Dorsal Root Ganglia Neurons for In Vitro Myelination Studies by Maurel, Patrice

“…The ability to understand in great details, at the molecular level, the process of myelination in the peripheral nervous system (PNS) is, in no minor part, due…”
Get more information

Zeb2 recruits HDAC–NuRD to inhibit Notch and controls Schwann cell differentiation and remyelination by Wu, Lai Man Natalie, Wang, Jincheng, Conidi, Andrea, Zhao, Chuntao, Wang, Haibo, Ford, Zachary, Zhang, Liguo, Zweier, Christiane, Ayee, Brian G, Maurel, Patrice, Zwijsen, An, Chan, Jonah R, Jankowski, Michael P, Huylebroeck, Danny, Lu, Q Richard

“…This study shows that the transcriptional regulator Zeb2 is required for the onset of peripheral myelination and remyelination. Zeb2 recruits HDAC1–HDAC2–NuRD…”
Get full text

p38 MAPK activation promotes denervated Schwann cell phenotype and functions as a negative regulator of Schwann cell differentiation and myelination by Yang, David P, Kim, Jihyun, Syed, Neeraja, Tung, Young-John, Bhaskaran, Ambily, Mindos, Thomas, Mirsky, Rhona, Jessen, Kristjan R, Maurel, Patrice, Parkinson, David B, Kim, Haesun A

“…Physical damage to the peripheral nerves triggers Schwann cell injury response in the distal nerves in an event termed Wallerian degeneration: the Schwann…”
Get full text

Soluble neuregulin-1 has bifunctional, concentration-dependent effects on Schwann cell myelination by Syed, Neeraja, Reddy, Kavya, Yang, David P, Taveggia, Carla, Salzer, James L, Maurel, Patrice, Kim, Haesun A

“…Members of the neuregulin-1 (Nrg1) growth factor family play important roles during Schwann cell development. Recently, it has been shown that the…”
Get full text

Nectin-like proteins mediate axon-Schwann cell interactions along the internode and are essential for myelination by Maurel, Patrice, Einheber, Steven, Galinska, Jolanta, Thaker, Pratik, Lam, Isabel, Rubin, Marina B, Scherer, Steven S, Murakami, Yoshinuri, Gutmann, David H, Salzer, James L

“…Axon-glial interactions are critical for the induction of myelination and the domain organization of myelinated fibers. Although molecular complexes that…”
Get full text

E-Cadherin enhances neuregulin signaling and promotes Schwann cell myelination by Basak, Sayantani, Desai, Darshan J., Rho, Esther H., Ramos, Roselle, Maurel, Patrice, Kim, Haesun A.

“…In myelinating Schwann cells, E‐cadherin is a component of the adherens junctions that stabilize the architecture of the noncompact myelin region. In other…”
Get full text

Tissue Inhibitor of Metalloproteinase-3 Promotes Schwann Cell Myelination by Kim, Jihyun, Elias, Anthony, Lee, Taeweon, Maurel, Patrice, Kim, Haesun A.

“…Tissue inhibitor of metalloproteinase-3 (TIMP-3) inhibits the activities of various metalloproteinases including matrix metalloproteinases and ADAM family…”
Get full text

Axonal Regulation of Schwann Cell Proliferation and Survival and the Initial Events of Myelination Requires PI 3-Kinase Activity by Maurel, Patrice, Salzer, James L

“…In this report, we have investigated the signaling pathways that are activated by, and mediate the effects of, the neuregulins and axonal contact in Schwann…”
Get full text

Differential expression of proteoglycans at central and peripheral nodes of Ranvier by Melendez-Vasquez, Carmen, Carey, David J., Zanazzi, George, Reizes, Ofer, Maurel, Patrice, Salzer, James L.

“…The nodes of Ranvier are regularly spaced gaps between myelin sheaths that are markedly enriched in voltage‐gated sodium channels and associated proteins…”
Get full text

Differential Regulation of Expression of Hyaluronan-Binding Proteoglycans in Developing Brain: Aggrecan, Versican, Neurocan, and Brevican by Milev, Peter, Maurel, Patrice, Chiba, Atsuro, Mevissen, Markus, Popp, Susanna, Yamaguchi, Yu, Margolis, Renée K., Margolis, Richard U.

“…We have used a slot-blot radioimmunoassay to quantitate the levels of hyaluronan-binding chondroitin sulfate proteoglycans in developing rat brain from…”
Get full text

Lentiviral Transduction of Rat Schwann Cells and Dorsal Root Ganglia Neurons for In Vitro Myelination Studies by Heffernan, Corey, Maurel, Patrice

“…Lentiviral transduction is a gene delivery method that provides numerous advantages over direct transfection and traditional retroviral or adenoviral delivery…”
Get more information

Localization of aggrecan and versican in the developing rat central nervous system by Popp, Susanna, Andersen, Julie S., Maurel, Patrice, Margolis, Richard U.

“…The localization of aggrecan and mRNA splice variants of versican in the developing rat central nervous system has been examined by using specific polyclonal…”
Get full text

Chondroitin sulfate proteoglycans in the developing central nervous system. I. Cellular sites of synthesis of neurocan and phosphacan by Engel, Margit, Maurel, Patrice, Margolis, Richard U., Margolis, Renée K.

“…We have used in situ hybridization histochemistry to examine the cellular sites of synthesis of two major nervous tissue proteoglycans, neurocan and…”
Get full text

Versican/PG-M Isoforms in Vascular Smooth Muscle Cells by Lemire, Joan M, Braun, Kathleen R, Maurel, Patrice, Kaplan, Elizabeth D, Schwartz, Stephen M, Wight, Thomas N

“…The expression of increased amounts of proteoglycans in the extracellular matrix may play a role in vascular stenosis and lipid retention. The large…”
Get full text

Mechanical stretch induces myelin protein loss in oligodendrocytes by activating Erk1/2 in a calcium‐dependent manner by Kim, Jihyun, Adams, Alexandra A., Gokina, Pradeepa, Zambrano, Brayan, Jayakumaran, Jeyanthan, Dobrowolski, Radek, Maurel, Patrice, Pfister, Bryan J., Kim, Haesun A.

“…Myelin loss in the brain is a common occurrence in traumatic brain injury (TBI) that results from impact‐induced acceleration forces to the head. Fast and…”
Get full text

TFEB/3 Govern Repair Schwann Cell Generation and Function Following Peripheral Nerve Injury by Patel, Akash A, Kim, Hyukmin, Ramesh, Raghu, Marquez, Anthony, Faraj, Moler M, Antikainen, Henri, Lee, Andrew S, Torres, Adriana, Khawaja, Imran M, Heffernan, Corey, Bonder, Edward M, Maurel, Patrice, Svaren, John, Son, Young-Jin, Dobrowolski, Radek, Kim, Haesun A

“…TFEB and TFE3 (TFEB/3), key regulators of lysosomal biogenesis and autophagy, play diverse roles depending on cell type. This study highlights a hitherto…”
Get more information

Cadm3 (Necl-1) interferes with the activation of the PI3 kinase/Akt signaling cascade and inhibits Schwann cell myelination in vitro: Cadm3 Inhibits Schwann Cell Myelination by Chen, Ming-Shuo, Kim, Hyosung, Jagot-Lacoussiere, Léonard, Maurel, Patrice

Get full text

Necl‐4/Cadm4 recruits Par‐3 to the Schwann cell adaxonal membrane by Meng, Xiaosong, Maurel, Patrice, Lam, Isabel, Heffernan, Corey, Stiffler, Michael A., McBeath, Gavin, Salzer, James L.

“…Interactions between axons and Schwann cells are essential for the acquisition of Schwann cell radial and longitudinal polarity and myelin sheath assembly. In…”
Get full text

Nectin-like 4 Complexes with Choline Transporter-like Protein-1 and Regulates Schwann Cell Choline Homeostasis and Lipid Biogenesis in Vitro by Heffernan, Corey, Jain, Mohit R., Liu, Tong, Kim, Hyosung, Barretto, Kevin, Li, Hong, Maurel, Patrice

“…Nectin-like 4 (NECL4, CADM4) is a Schwann cell-specific cell adhesion molecule that promotes axo-glial interactions. In vitro and in vivo studies have shown…”
Get full text

Cadm3 (Necl-1) interferes with the activation of the PI3 kinase/Akt signaling cascade and inhibits Schwann cell myelination in vitro by Chen, Ming-Shuo, Kim, Hyosung, Jagot-Lacoussiere, Léonard, Maurel, Patrice

“…Axo‐glial interactions are critical for myelination and the domain organization of myelinated fibers. Cell adhesion molecules belonging to the Cadm family, and…”
Get full text