Search Results - "Mauna, Jocelyn C."
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NUP62 localizes to ALS/FTLD pathological assemblies and contributes to TDP-43 insolubility
Published in Nature communications (13-06-2022)“…A G4C2 hexanucleotide repeat expansion in the C9orf72 gene is the most common genetic cause of ALS and FTLD (C9-ALS/FTLD) with cytoplasmic TDP-43 inclusions…”
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Protein phosphatases 1 and 2A are both required for long-term depression and associated dephosphorylation of cAMP response element binding protein in hippocampal area CA1 in vivo
Published in Hippocampus (01-10-2011)“…Evidence shows that the serine/threonine protein phosphatase 1 (PP1) plays a critical role in synaptic plasticity and memory. Little is known about the…”
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RNA Binding Antagonizes Neurotoxic Phase Transitions of TDP-43
Published in Neuron (Cambridge, Mass.) (17-04-2019)“…TDP-43 proteinopathy is a pathological hallmark of amyotrophic lateral sclerosis and frontotemporal dementia where cytoplasmic TDP-43 inclusions are observed…”
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Cue-Elicited Reward-Seeking Requires Extracellular Signal-Regulated Kinase Activation in the Nucleus Accumbens
Published in The Journal of neuroscience (06-02-2008)“…The motivation to seek out rewards can come under the control of stimuli associated with reward delivery. The ability of cues to motivate reward-seeking…”
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Axotomy-induced neurotrophic withdrawal causes the loss of phenotypic differentiation and downregulation of NGF signalling, but not death of septal cholinergic neurons
Published in Molecular neurodegeneration (19-01-2010)“…Septal cholinergic neurons account for most of the cholinergic innervations of the hippocampus, playing a key role in the regulation of hippocampal synaptic…”
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Appetitive Cue-Evoked ERK Signaling in the Nucleus Accumbens Requires NMDA and D1 Dopamine Receptor Activation and Regulates CREB Phosphorylation
Published in Learning & memory (Cold Spring Harbor, N.Y.) (01-11-2014)“…Conditioned stimuli (CS) can modulate reward-seeking behavior. This modulatory effect can be maladaptive and has been implicated in excessive reward seeking…”
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Critical Involvement of Postsynaptic Protein Kinase Activation in Long-Term Potentiation at Hippocampal Mossy Fiber Synapses on CA3 Interneurons
Published in The Journal of neuroscience (24-02-2010)“…Hippocampal mossy fiber (MF) synapses on area CA3 lacunosum-moleculare (L-M) interneurons are capable of undergoing a Hebbian form of NMDA receptor…”
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Appetitive Pavlovian conditioned stimuli increase CREB phosphorylation in the nucleus accumbens
Published in Neurobiology of learning and memory (01-10-2009)“…The transcription factor cAMP response element-binding protein (CREB) in the nucleus accumbens (NAc) has been shown to regulate an animal’s behavioral…”
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Properties and functional implications of Ih in hippocampal area CA3 interneurons
Published in Pflügers Archiv (01-12-2011)“…The present study examines the biophysical properties and functional implications of I h in hippocampal area CA3 interneurons with somata in strata radiatum…”
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Properties and functional implications of I h in hippocampal area CA3 interneurons
Published in Pflügers Archiv (01-12-2011)Get full text
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Properties and functional implications of I ^sub h^ in hippocampal area CA3 interneurons
Published in Pflügers Archiv (01-12-2011)“…The present study examines the biophysical properties and functional implications of I ^sub h^ in hippocampal area CA3 interneurons with somata in strata…”
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Properties and functional implications of I sub(h) in hippocampal area CA3 interneurons
Published in Pflügers Archiv (01-12-2011)“…The present study examines the biophysical properties and functional implications of I sub(h) in hippocampal area CA3 interneurons with somata in strata…”
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13
Properties and functional implications of I (h) in hippocampal area CA3 interneurons
Published in Pflügers Archiv (01-12-2011)“…The present study examines the biophysical properties and functional implications of I (h) in hippocampal area CA3 interneurons with somata in strata radiatum…”
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