Search Results - "Maulloo, Chitavi D"
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Lymph Node-Targeted Synthetically Glycosylated Antigen Leads to Antigen-Specific Immunological Tolerance
Published in Frontiers in immunology (24-09-2021)“…Inverse vaccines that tolerogenically target antigens to antigen-presenting cells (APCs) offer promise in prevention of immunity to allergens and protein drugs…”
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Synthetically glycosylated antigens for the antigen-specific suppression of established immune responses
Published in Nature biomedical engineering (01-09-2023)“…Inducing antigen-specific tolerance during an established immune response typically requires non-specific immunosuppressive signalling molecules. Hence,…”
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Glycosylation-modified antigens as a tolerance-inducing vaccine platform prevent anaphylaxis in a pre-clinical model of food allergy
Published in Cell reports. Medicine (16-01-2024)“…The only FDA-approved oral immunotherapy for a food allergy provides protection against accidental exposure to peanuts. However, this therapy often causes…”
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Synthetically glycosylated antigens as an inverse vaccine platform to prevent and treat food allergies
Published in The Journal of immunology (1950) (01-05-2022)“…Abstract The only FDA-approved oral immunotherapy for a food allergy provides protection against accidental exposure to peanuts. However, this therapy often…”
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Targeting antigen to lymph node lymphatic endothelial cells under steady-state to promote archiving and memory
Published in The Journal of immunology (1950) (01-05-2019)“…Abstract Lymphatic endothelial cells (LECs) have been shown to archive antigen (Ag), i.e. retain Ag in its native form, for weeks after exposure. We have…”
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