Search Results - "Maulik, D"

Monocyte-Directed RNAi Targeting CCR2 Improves Infarct Healing in Atherosclerosis-Prone Mice by Majmudar, Maulik D, Keliher, Edmund J, Heidt, Timo, Leuschner, Florian, Truelove, Jessica, Sena, Brena F, Gorbatov, Rostic, Iwamoto, Yoshiko, Dutta, Partha, Wojtkiewicz, Gregory, Courties, Gabriel, Sebas, Matt, Borodovsky, Anna, Fitzgerald, Kevin, Nolte, Marc W, Dickneite, Gerhard, Chen, John W, Anderson, Daniel G, Swirski, Filip K, Weissleder, Ralph, Nahrendorf, Matthias

“…BACKGROUND—Exaggerated and prolonged inflammation after myocardial infarction (MI) accelerates left ventricular remodeling. Inflammatory pathways may present a…”
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Using Digital Health Technology to Better Generate Evidence and Deliver Evidence-Based Care by Sharma, Abhinav, Harrington, Robert A., McClellan, Mark B., Turakhia, Mintu P., Eapen, Zubin J., Steinhubl, Steven, Mault, James R., Majmudar, Maulik D., Roessig, Lothar, Chandross, Karen J., Green, Eric M., Patel, Bakul, Hamer, Andrew, Olgin, Jeffrey, Rumsfeld, John S., Roe, Matthew T., Peterson, Eric D.

“…As we enter the information age of health care, digital health technologies offer significant opportunities to optimize both clinical care delivery and…”
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Protective effects of gelsolin in acute pulmonary thromboembolism and thrombosis in the carotid artery of mice by Gupta, Ashok Kumar, Chopra, Bhupinder Singh, Vaid, Bhavna, Sagar, Amin, Raut, Sachin, Badmalia, Maulik D, Ashish, Khatri, Neeraj

“…The present study provides first evidence on the role of plasma gelsolin in protecting pulmonary thromboembolism and thrombosis in a mouse model. Gelsolin is…”
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Targeting Xist with compounds that disrupt RNA structure and X inactivation by Aguilar, Rodrigo, Spencer, Kerrie B., Kesner, Barry, Rizvi, Noreen F., Badmalia, Maulik D., Mrozowich, Tyler, Mortison, Jonathan D., Rivera, Carlos, Smith, Graham F., Burchard, Julja, Dandliker, Peter J., Patel, Trushar R., Nickbarg, Elliott B., Lee, Jeannie T.

“…Although more than 98% of the human genome is non-coding 1 , nearly all of the drugs on the market target one of about 700 disease-related proteins. The…”
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Host Transcription Factors in Hepatitis B Virus RNA Synthesis by Turton, Kristi L, Meier-Stephenson, Vanessa, Badmalia, Maulik D, Coffin, Carla S, Patel, Trushar R

“…The hepatitis B virus (HBV) chronically infects over 250 million people worldwide and is one of the leading causes of liver cancer and hepatocellular…”
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Cardiovascular molecular imaging: the road ahead by Majmudar, Maulik D, Nahrendorf, Matthias

“…Despite significant advancements in medical and device-based therapies, cardiovascular disease remains the number one cause of death in the United States…”
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Bioinformatic Analysis of Structure and Function of LIM Domains of Human Zyxin Family Proteins by Siddiqui, M Quadir, Badmalia, Maulik D, Patel, Trushar R

“…Members of the human Zyxin family are LIM domain-containing proteins that perform critical cellular functions and are indispensable for cellular integrity…”
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Shape–function insights into bifunctional O-GlcNActransferase of Listeria monocytogenes EGD-e by Choudhary, Pravinkumar, Badmalia, Maulik D, Rao, Alka

“…Abstract O-GlcNAcylation is an important post-translational modification of proteins. O-GlcNAcylated proteins have crucial roles in several cellular contexts…”
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Observational study on wearable biosensors and machine learning-based remote monitoring of COVID-19 patients by Un, Ka-Chun, Wong, Chun-Ka, Lau, Yuk-Ming, Lee, Jeffrey Chun-Yin, Tam, Frankie Chor-Cheung, Lai, Wing-Hon, Lau, Yee-Man, Chen, Hao, Wibowo, Sandi, Zhang, Xiaozhu, Yan, Minghao, Wu, Esther, Chan, Soon-Chee, Lee, Sze-Ming, Chow, Augustine, Tong, Raymond Cheuk-Fung, Majmudar, Maulik D., Rajput, Kuldeep Singh, Hung, Ivan Fan-Ngai, Siu, Chung-Wah

“…Patients infected with SARS-CoV-2 may deteriorate rapidly and therefore continuous monitoring is necessary. We conducted an observational study involving…”
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Polymeric Nanoparticle PET/MR Imaging Allows Macrophage Detection in Atherosclerotic Plaques by Majmudar, Maulik D, Yoo, Jeongsoo, Keliher, Edmund J, Truelove, Jessica J, Iwamoto, Yoshiko, Sena, Brena, Dutta, Partha, Borodovsky, Anna, Fitzgerald, Kevin, Di Carli, Marcelo F, Libby, Peter, Anderson, Daniel G, Swirski, Filip K, Weissleder, Ralph, Nahrendorf, Matthias

“…RATIONALE:Myeloid cell content in atherosclerotic plaques associates with rupture and thrombosis. Thus, imaging of lesional monocytes and macrophages could…”
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Visualizing Temperature Mediated Activation of Gelsolin and Its Deactivation By Pip2: A Saxs Based Study by Badmalia, Maulik D., Singh, Shikha, Garg, Renu, Ashish

“…This is the first report describing temperature based initiation of gelsolin’s F-actin depolymerization activity, even in absence of free Ca 2+ or low pH…”
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2017 Roadmap for Innovation-ACC Health Policy Statement on Healthcare Transformation in the Era of Digital Health, Big Data, and Precision Health: A Report of the American College of Cardiology Task Force on Health Policy Statements and Systems of Care by Bhavnani, Sanjeev P, Parakh, Kapil, Atreja, Ashish, Druz, Regina, Graham, Garth N, Hayek, Salim S, Krumholz, Harlan M, Maddox, Thomas M, Majmudar, Maulik D, Rumsfeld, John S, Shah, Bimal R

“…Generate Evidence-Based Best Practices for Guideline Consensus and Patient Care It is unclear how the healthcare community should develop the resources…”
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Antioxidant and Wound Healing Property of Gelsolin in 3T3-L1 Cells by Khatri, Neeraj, Badmalia, Maulik D., Sagar, Amin, Raut, Sachin, Chopra, Bhupinder Singh, Vaid, Bhavna, Ashish, Renu

“…Delineation of factors which affect wound healing would be of immense value to enable on-time or early healing and reduce comorbidities associated with…”
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Heat induces end to end repetitive association in P. furiosus L-asparaginase which enables its thermophilic property by Sharma, Pankaj, Tomar, Rachana, Yadav, Shivpratap Singh, Badmalia, Maulik D, Nath, Samir Kumar, Ashish, Kundu, Bishwajit

“…It remains undeciphered how thermophilic enzymes display enhanced stability at elevated temperatures. Taking L-asparaginase from P. furiosus (PfA) as an…”
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Myocardial infarction accelerates atherosclerosis by Dutta, Partha, Courties, Gabriel, Wei, Ying, Leuschner, Florian, Gorbatov, Rostic, Robbins, Clinton S., Iwamoto, Yoshiko, Thompson, Brian, Carlson, Alicia L., Heidt, Timo, Majmudar, Maulik D., Lasitschka, Felix, Etzrodt, Martin, Waterman, Peter, Waring, Michael T., Chicoine, Adam T., van der Laan, Anja M., Niessen, Hans W. M., Piek, Jan J., Rubin, Barry B., Butany, Jagdish, Stone, James R., Katus, Hugo A., Murphy, Sabina A., Morrow, David A., Sabatine, Marc S., Vinegoni, Claudio, Moskowitz, Michael A., Pittet, Mikael J., Libby, Peter, Lin, Charles P., Swirski, Filip K., Weissleder, Ralph, Nahrendorf, Matthias

“…During progression of atherosclerosis, myeloid cells destabilize lipid-rich plaques in the arterial wall and cause their rupture, thus triggering myocardial…”
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Postpartum haemorrhage refractory to uterotonics by Vilchez, G, Patel, N, Maulik, D

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Visualizing Temperature Mediated Activation of Gelsolin and Its Deactivation By Pip 2 : A Saxs Based Study by Badmalia, Maulik D, Singh, Shikha, Garg, Renu, Ashish

“…This is the first report describing temperature based initiation of gelsolin's F-actin depolymerization activity, even in absence of free Ca or low pH. Small…”
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Smartphone camera based assessment of adiposity: a validation study by Majmudar, Maulik D., Chandra, Siddhartha, Yakkala, Kiran, Kennedy, Samantha, Agrawal, Amit, Sippel, Mark, Ramu, Prakash, Chaudhri, Apoorv, Smith, Brooke, Criminisi, Antonio, Heymsfield, Steven B., Stanford, Fatima Cody

“…Body composition is a key component of health in both individuals and populations, and excess adiposity is associated with an increased risk of developing…”
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Identification and characterisation of G-quadruplexes from viral genomes by Gemmill, Darren L., Pereira, Higor S., Badmalia, Maulik D., Nelson, Corey R., Wolfinger, Michael T., Patel, Trushar R.

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Bonsai Gelsolin Survives Heat Induced Denaturation by Forming β-Amyloids which Leach Out Functional Monomer by Badmalia, Maulik D., Sharma, Pankaj, Yadav, Shiv Pratap Singh, Singh, Shikha, Khatri, Neeraj, Garg, Renu, Ashish

“…Here, we report that minimal functional gelsolin i . e . fragment 28–161 can display F-actin depolymerizing property even after heating the protein to 80 °C…”
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