Search Results - "Mauldin, Jeremy P"
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Tumor endothelial marker 8 promotes cancer progression and metastasis
Published in Oncotarget (10-07-2018)“…Every year more than 8 million people suffer from cancer-related deaths worldwide [1]. Metastasis, the spread of cancer to distant sites, accounts for 90% of…”
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Reduction in ABCG1 in Type 2 Diabetic Mice Increases Macrophage Foam Cell Formation
Published in The Journal of biological chemistry (28-07-2006)“…Atherosclerosis development is accelerated severalfold in patients with Type 2 diabetes. In the initial stages of disease, monocytes transmigrate into the…”
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Reduced Expression of ATP-Binding Cassette Transporter G1 Increases Cholesterol Accumulation in Macrophages of Patients With Type 2 Diabetes Mellitus
Published in Circulation (New York, N.Y.) (27-05-2008)“…Patients with type 2 diabetes mellitus are at increased risk for the development of atherosclerosis. A pivotal event in the development of atherosclerosis is…”
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Cytotoxicity of human recombinant arginase I (Co)-PEG5000 in the presence of supplemental L-citrulline is dependent on decreased argininosuccinate synthetase expression in human cells
Published in Anti-cancer drugs (01-01-2012)“…Human recombinant arginase I cobalt [HuArgI (Co)] coupled with polyethylene glycol 5000 [HuArgI (Co)-PEG5000] has shown potent in-vitro depletion of arginine…”
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Recombinant Human Arginase Toxicity in Mice Is Reduced by Citrulline Supplementation
Published in Translational oncology (01-02-2012)“…Human recombinant arginase I cobalt coupled to polyethylene glycol 5000 (HuArg I [Co]-PEG5000) achieved potent in vitro depletion of arginine from tissue…”
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In-vivo evaluation of human recombinant Co-arginase against A375 melanoma xenografts
Published in Melanoma research (01-12-2014)“…Metastatic melanoma is a deadly form of cancer with few therapeutic options and the cause of more than 9480 deaths annually in the USA alone. Novel treatment…”
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Abstract B17: Disrupting tumor growth through targeting TEM8
Published in Cancer research (Chicago, Ill.) (01-08-2016)“…Abstract Tumor Endothelial Marker 8 (TEM8) is an integrin-like cell-surface receptor originally identified being specific to tumor endothelial cells in…”
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An Update On The Clinical Activity Of Resimmune, a Targeted Therapy Directed To CD3 Receptor, In Patients With Cutaneous T Cell Lymphomas--CTCL
Published in Blood (15-11-2013)“…Cutaneous T cell lymphoma—CTCL is a malignancy of skin-tropic T cells. CTCL cells have ubiquitous overexpression of CD3. Although uncommon, CTCL has been…”
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An Update On The Robust Clinical Activity Of SL-401, a Targeted Therapy Directed To The Interleukin-3 Receptor On Cancer Stem Cells and Tumor Bulk, In Patients With Blastic Plasmacytoid Dendritic Cell Neoplasm (BPDCN)
Published in Blood (15-11-2013)“…Blastic Plasmacytoid Dendritic Cell Neoplasm (BPDCN) is an aggressive hematologic malignancy derived from plasmacytoid dendritic cells. The clinical…”
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The Murine ABCG1 Gene Can Be Regulated In Part By Glucose Sensitive E‐boxes and the Transcriptional Regulators E47 and Id3
Published in The FASEB journal (01-04-2007)“…The ABC transporter, ABCG1, plays a major role in macrophage reverse cholesterol transport. Here we show that overexpression of ABCG1 in diabetic db/db…”
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Reduced Expression of ABCG1 Increases Cholesterol Accumulation in Macrophages of Patients with Type 2 Diabetes
Published in Circulation (New York, N.Y.) (19-05-2008)Get full text
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Recombinant Human Arginase Toxicity in Mice Is Reduced by Citrulline Supplementation1
Published in Translational oncology (01-02-2012)“…Human recombinant arginase I cobalt coupled to polyethylene glycol 5000 (HuArg I [Co]-PEG5000) achieved potent in vitro depletion of arginine from tissue…”
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