Search Results - "Mauen, Sébastien"

Proof of principle: quality control of therapeutic cell preparations using senescence-associated DNA-methylation changes by Schellenberg, Anne, Mauen, Sébastien, Koch, Carmen Mareike, Jans, Ralph, de Waele, Peter, Wagner, Wolfgang

“…Tracking of replicative senescence is of fundamental relevance in cellular therapy. Cell preparations - such as mesenchymal stromal cells (MSCs) - undergo…”
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The Ets transcription factors of the PEA3 group: Transcriptional regulators in metastasis by de Launoit, Yvan, Baert, Jean-Luc, Chotteau-Lelievre, Anne, Monte, Didier, Coutte, Laurent, Mauen, Sébastien, Firlej, Virginie, Degerny, Cindy, Verreman, Kathye

“…The PEA3 group is composed of three highly conserved Ets transcription factors: Erm, Er81, and Pea3. These proteins regulate transcription of multiple genes,…”
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A Genetic Screen Identifies Topoisomerase 1 as a Regulator of Senescence by HUMBERT, Nicolas, MARTIEN, Sébastien, AUGERT, Arnaud, DA COSTA, Marco, MAUEN, Sébastien, ABBADIE, Corinne, DE LAUNOIT, Yvan, GIL, Jesús, BERNARD, David

“…Normal cell growth can be permanently blocked when cells enter a state known as senescence. This phenomenon can be triggered by various stresses, such as…”
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Clinical Grade Manufacture of CYAD-101, a NKG2D-based, First in Class, Non–Gene-edited Allogeneic CAR T-Cell Therapy by Michaux, Alexandre, Mauën, Sébastien, Breman, Eytan, Dheur, Marie-Sophie, Twyffels, Laure, Saerens, Laura, Jacques-Hespel, Céline, Gauthy, Emilie, Agaugué, Sophie, Gilham, David E., Sotiropoulou, Panagiota A.

“…Allogeneic chimeric antigen receptor (CAR) T holds the promise of taking this therapeutic approach to broader patient populations while avoiding the intensive…”
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Expression, purification, and structural prediction of the Ets transcription factor ERM by Mauen, Sébastien, Huvent, Isabelle, Raussens, Vincent, Demonte, Dominique, Baert, Jean-Luc, Tricot, Catherine, Ruysschaert, Jean-Marie, Van Lint, Carine, Moguilevsky, Nicole, de Launoit, Yvan

“…The PEA3 group within the Ets family comprises PEA3, ER81, and ERM, three transcription factors of about 500 residues. These factors are highly conserved in…”
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Expression of the Ets transcription factor Erm is regulated through a conventional PKC signaling pathway in the Molt4 lymphoblastic cell line by T’Sas, France, Brenner, Carmen, Mauen, Sébastien, Putmans, Pascale, Monté, Didier, Van Lint, Carine, Moser, Muriel, Baert, Jean-Luc, de Launoit, Yvan

“…Erm, a member of the PEA3 group within the Ets family of transcription factors, is expressed in murine and human lymphocytes. Here, we show that in the human…”
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PEA3 family of transcription factors and the regulation of oncogenesis by de Launoit, Yvan, Baert, Jean-Luc, Chotteau-Lelievre, Anne, Monte, Didier, Coutte, Laurent, Mauen, Sébastien, Firlej, Virginie, Degerny, Cindy, Verreman, Kathye

“…Erm, Er81, and Pea3 are the three members of the PEA3 group which belong to the Ets transcription factors family. These proteins regulate transcription of…”
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Cardiopoietic index predicts heart repair fitness of patient-derived stem cells by Crespo-Diaz, Ruben, Yamada, Satsuki, Bartunek, Jozef, Perez-Terzic, Carmen, de Waele, Peter, Mauën, Sébastien, Terzic, Andre, Behfar, Atta

“…Stem cell therapy shows promise for regeneration in heart disease, yet interpatient variability challenges implementation into practice. To establish a…”
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CYAD-101: An innovative non-gene edited allogeneic CAR-T for solid tumor cancer therapy by Prenen, Hans, Dekervel, Jeroen, Anguille, Sébastien, Hendlisz, Alain, Michaux, Alexandre, Sotiropoulou, Panagiota A, Gilham, David Edward, Mauen, Sébastien, Snykers, Sarah, Cerf, Emilie, Lonez, Caroline, Flament, Anne, Lehmann, Frederic, Van Cutsem, Eric

“…Abstract only 3032 Background: In contrast to autologous CAR-T cell therapies, allogeneic donor-derived CAR-T cells can be banked and used in a timely fashion…”
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TCR inhibitory molecule as a promising allogeneic NKG2D CAR-t cell approach by Gilham, David Edward, Michaux, Alexandre, Breman, Eytan, Mauen, Sébastien, Bolsée, Jennifer, Huberty, Fanny, Marijsse, Jérôme, Violle, Benjamin, Jacques-Hespel, Céline, Marchand, Céline, Ramelot, Nancy, N'Guyen, Thuy, Houssa, Julien, Agaugue, Sophie

“…Abstract only…”
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Overcoming Target Driven Fratricide for T Cell Therapy by Breman, Eytan, Demoulin, Benjamin, Agaugué, Sophie, Mauën, Sebastien, Michaux, Alexandre, Springuel, Lorraine, Houssa, Julien, Huberty, Fanny, Jacques-Hespel, Céline, Marchand, Céline, Marijsse, Jérôme, Nguyen, Thuy, Ramelot, Nancy, Violle, Benjamin, Daro, Dorothée, De Waele, Peter, Gilham, David E, Steenwinckel, Valérie

“…Chimeric Antigen Receptor (CAR) T cells expressing the fusion of the NKG2D protein with CD3ζ (NKG2D-CAR T Cells) acquire a specificity for stress-induced…”
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Clinical Grade Manufacture of CYAD-101, a NKG2D-based, First in Class, Non–Gene-edited Allogeneic CAR T-Cell Therapy by Michaux, Alexandre, Mauën, Sébastien, Breman, Eytan, Dheur, Marie-Sophie, Twyffels, Laure, Saerens, Laura, Jacques-Hespel, Céline, Gauthy, Emilie, Agaugué, Sophie, Gilham, David E., Sotiropoulou, Panagiota A.

“…Allogeneic chimeric antigen receptor (CAR) T holds the promise of taking this therapeutic approach to broader patient populations while avoiding the intensive…”
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Les facteurs de transcription du groupe PEA3 : régulateurs transcriptionnels dans le processus de cancérisation by DE LAUNOIT, Yvan, BAERT, Jean-Luc, CHOTTEAU-LELIEVRE, Anne, MONTE, Didier, COUTTE, Laurent, MAUEN, Sébastien, FIRLEJ, Virginie, DEGERNY, Cindy, VERREMAN, Kathye

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