Search Results - "Matzke, M A"
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Transcriptional silencing and promoter methylation triggered by double-stranded RNA
Published in The EMBO journal (02-10-2000)“…Double‐stranded RNA induces a post‐transcriptional gene silencing process, termed RNAi, in diverse organisms. It is shown here that transcriptional gene…”
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How and why do plants inactivate homologous (trans)genes?
Published in Plant physiology (Bethesda) (01-03-1995)Get full text
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Integrated pararetroviral sequences define a unique class of dispersed repetitive DNA in plants
Published in Proceedings of the National Academy of Sciences - PNAS (09-11-1999)“…Although integration of viral DNA into host chromosomes occurs regularly in bacteria and animals, there are few reported cases in plants, and these involve…”
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Transgene silencing by the host genome defense: implications for the evolution of epigenetic control mechanisms in plants and vertebrates
Published in Plant molecular biology (01-06-2000)“…Increasing evidence supports the idea that various transgene silencing phenomena reflect the activity of diverse host defense responses that act ordinarily on…”
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5
Endogenous viral sequences and their potential contribution to heritable virus resistance in plants
Published in The EMBO journal (01-02-2002)“…Tobacco endogenous pararetroviruses (TEPRVs) represent the first virus‐derived repetitive sequence family found in plants. The sequence conservation of TEPRVs…”
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Gene silencing mediated by promoter homology occurs at the level of transcription and results in meiotically heritable alterations in methylation and gene activity
Published in The Plant journal : for cell and molecular biology (01-02-1996)“…The promoter homology‐dependent inactivation of a 35Spro‐hygromycin phosphotransferase (hpt) gene, which is present at the H2 locus, by the multipurpose 271…”
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Reversible methylation and inactivation of marker genes in sequentially transformed tobacco plants
Published in The EMBO journal (01-03-1989)“…Doubly transformed tobacco plants were obtained following sequential transformation steps using two T‐DNAs encoding different selection and screening markers:…”
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8
Exploring and explaining epigenetic effects
Published in Trends in genetics (01-08-1997)“…Epigenetic phenomena in diverse organisms comprise some of the most intriguing and actively investigated problems in genetics. The term `epigenetics' was…”
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Epigenetic silencing of plant transgenes as a consequence of diverse cellular defence responses
Published in Cellular and molecular life sciences : CMLS (01-01-1998)“…Linked and unlinked copies of transgenes and related endogenous genes in plants can be epigenetically silenced by homology-based mechanisms that operate at…”
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10
Production of aberrant promoter transcripts contributes to methylation and silencing of unlinked homologous promoters in trans
Published in The EMBO journal (04-01-1999)“…Previous work has suggested that de novo methylation of plant nuclear genes can be triggered by an RNA–DNA interaction. To test whether transcription of a…”
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11
Rapid structural and epigenetic changes in polyploid and aneuploid genomes
Published in BioEssays (01-09-1999)“…Recent work with plants has demonstrated that genome instability can be triggered by a change in chromosome number arising from either whole genome…”
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The use of combined FISH/GISH in conjunction with DAPI counterstaining to identify chromosomes containing transgene inserts in amphidiploid tobacco
Published in Chromosoma (01-10-1996)“…We have used combined fluorescent and genomic in situ hybridization (FISH/GISH) together with 4',6-diamidino-2-phenylindole (DAPI) counterstaining to determine…”
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13
Homology-dependent gene silencing in transgenic plants: what does it really tell us?
Published in Trends in genetics (1995)“…Few recent developments have created more of a stir among plant molecular biologists than the discovery that the presence of multiple copies of homologous…”
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14
Host defenses to transposable elements and the evolution of genomic imprinting
Published in Cytogenetic and genome research (01-01-2005)“…Genomic imprinting is the differential expression of maternally and paternally inherited alleles of specific genes. Several organismic level hypotheses have…”
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15
Resistance of RNA-mediated TGS to HC-Pro, a viral suppressor of PTGS, suggests alternative pathways for dsRNA processing
Published in Current biology (24-07-2001)“…In plants, double-stranded (ds) RNA that is degraded to small (sm) RNAs that are ∼23 nucleotides in length can trigger the degradation of homologous RNAs in…”
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Polyploidy and transposons
Published in Trends in ecology & evolution (Amsterdam) (01-06-1998)Get full text
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Differential inactivation and methylation of a transgene in plants by two suppressor loci containing homologous sequences
Published in Plant molecular biology (01-05-1991)“…In a previous study on doubly transformed tobacco plants, we observed the unexpected inactivation in trans of T-DNA-I (encoding KanrNOS) following the…”
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18
Cloning Problems Don't Surprise Plant Biologists
Published in Science (American Association for the Advancement of Science) (30-06-2000)Get full text
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Homology-dependent gene silencing in transgenic plants: epistatic silencing loci contain multiple copies of methylated transgenes
Published in Molecular & general genetics (02-08-1994)“…Previous work has shown that two homologous, unlinked transgene loci can interact in plant nuclei, leading to non-reciprocal trans-inactivation and methylation…”
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Epigenetics: Regulation Through Repression
Published in Science (American Association for the Advancement of Science) (15-10-1999)“…Epigenetics is the study of heritable changes in gene expression that occur without a change in DNA sequence. Epigenetic phenomena have major economic and…”
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