Search Results - "Matzen, Jason T."

Suppressors of Superoxide-H2O2 Production at Site IQ of Mitochondrial Complex I Protect against Stem Cell Hyperplasia and Ischemia-Reperfusion Injury by Brand, Martin D., Goncalves, Renata L.S., Orr, Adam L., Vargas, Leonardo, Gerencser, Akos A., Borch Jensen, Martin, Wang, Yves T., Melov, Simon, Turk, Carolina N., Matzen, Jason T., Dardov, Victoria J., Petrassi, H. Michael, Meeusen, Shelly L., Perevoshchikova, Irina V., Jasper, Heinrich, Brookes, Paul S., Ainscow, Edward K.

“…Using high-throughput screening we identified small molecules that suppress superoxide and/or H2O2 production during reverse electron transport through…”
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In silico activity profiling reveals the mechanism of action of antimalarials discovered in a high-throughput screen by Plouffe, David, Brinker, Achim, McNamara, Case, Henson, Kerstin, Kato, Nobutaka, Kuhen, Kelli, Nagle, Advait, Adrián, Francisco, Matzen, Jason T, Anderson, Paul, Nam, Tae-gyu, Gray, Nathanael S, Chatterjee, Arnab, Janes, Jeff, Yan, S. Frank, Trager, Richard, Caldwell, Jeremy S, Schultz, Peter G, Zhou, Yingyao, Winzeler, Elizabeth A

“…The growing resistance to current first-line antimalarial drugs represents a major health challenge. To facilitate the discovery of new antimalarials, we have…”
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Suppressors of superoxide production from mitochondrial complex III by Orr, Adam L, Vargas, Leonardo, Turk, Carolina N, Baaten, Janine E, Matzen, Jason T, Dardov, Victoria J, Attle, Stephen J, Li, Jing, Quackenbush, Douglas C, Goncalves, Renata L S, Perevoshchikova, Irina V, Petrassi, H Michael, Meeusen, Shelly L, Ainscow, Edward K, Brand, Martin D

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An Efficient Rapid System for Profiling the Cellular Activities of Molecular Libraries by Melnick, Jonathan S., Janes, Jeff, Kim, Sungjoon, Chang, Jim Y., Sipes, Daniel G., Gunderson, Drew, Jarnes, Laura, Matzen, Jason T., Garcia, Michael E., Hood, Tami L., Beigi, Ronak, Xia, Gang, Harig, Richard A., Asatryan, Hayk, Yan, S. Frank, Zhou, Yingyao, Gu, Xiang-Ju, Saadat, Alham, Zhou, Vicki, King, Frederick J., Shaw, Christopher M., Su, Andrew I., Downs, Robert, Gray, Nathanael S., Schultz, Peter G., Warmuth, Markus, Caldwell, Jeremy S.

“…Rapid quantitative methods for characterizing small molecules, peptides, proteins, or RNAs in a broad array of cellular assays would allow one to discover new…”
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Suppressors of Superoxide-H 2 O 2 Production at Site I Q of Mitochondrial Complex I Protect against Stem Cell Hyperplasia and Ischemia-Reperfusion Injury by Brand, Martin D, Goncalves, Renata L S, Orr, Adam L, Vargas, Leonardo, Gerencser, Akos A, Borch Jensen, Martin, Wang, Yves T, Melov, Simon, Turk, Carolina N, Matzen, Jason T, Dardov, Victoria J, Petrassi, H Michael, Meeusen, Shelly L, Perevoshchikova, Irina V, Jasper, Heinrich, Brookes, Paul S, Ainscow, Edward K

“…Using high-throughput screening we identified small molecules that suppress superoxide and/or H O production during reverse electron transport through…”
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Suppressors of superoxide production from mitochondrial complex III by Orr, Adam L, Vargas, Leonardo, Turk, Carolina N, Baaten, Janine E, Matzen, Jason T, Dardov, Victoria J, Attle, Stephen J, Li, Jing, Quackenbush, Douglas C, Goncalves, Renata L S, Perevoshchikova, Irina V, Petrassi, H Michael, Meeusen, Shelly L, Ainscow, Edward K, Brand, Martin D

“…High-throughput chemical screening identified several groups of compounds that selectively block superoxide production from the outer Q-binding site of…”
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