Search Results - "Matys, Ronald"

GRP Receptor-Targeted PET of a Rat Pancreas Carcinoma Xenograft in Nude Mice with a 68Ga-Labeled Bombesin(6-14) Analog by Schuhmacher, Jochen, Zhang, Hanwen, Doll, Josef, Macke, Helmut R, Matys, Ronald, Hauser, Harald, Henze, Marcus, Haberkorn, Uwe, Eisenhut, Michael

“…Bombesin (BN), a 14-amino-acid peptide, shows high affinity for the human gastrin-releasing peptide receptor (GRP-r), which is overexpressed on several types…”
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Pretargeting of human mammary carcinoma xenografts with bispecific anti-MUC1/anti-Ga chelate antibodies and immunoscintigraphy with PET by SCHUHMACHER, Jochen, KLIVENYI, Gabor, KAUL, Sepp, HENZE, Marcus, MATYS, Ronald, HAUSER, Harald, CLORIUS, John

“…We recently demonstrated the feasibility of combining enhanced tumor-to-tissue contrast and PET imaging for immunoscintigraphic tumor localization in pancreas…”
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Bispecific tandem diabody for tumor therapy with improved antigen binding and pharmacokinetics by Kipriyanov, Sergey M, Moldenhauer, Gerhard, Schuhmacher, Jochen, Cochlovius, Björn, Von der Lieth, Claus-Wilhelm, Matys, E.Ronald, Little, Melvyn

“…To increase the valency, stability and therapeutic potential of bispecific antibodies, we designed a novel recombinant molecule that is bispecific and…”
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Multistep tumor targeting in nude mice using bispecific antibodies and a Gallium chelate suitable for immunoscintigraphy with positron emission tomography by SCHUHMACHER, J, KLIVENYI, G, MATYS, R, STADLER, M, REGIERT, T, HAUSER, H, DOLL, J, MAIER-BORST, W, ZÖLLER, M

“…To improve tumor:tissue ratios in immunoscintigraphy, a three-step targeting method has been developed. The reagents used were (a) a radioactive, low molecular…”
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Gallium-68 Chelate Imaging of Human Colon Carcinoma Xenografts Pretargeted with Bispecific Anti-CD44V6/Anti-Gallium Chelate Antibodies by Klivenyi, Gabor, Schuhmacher, Jochen, Patzelt, Erik, Hauser, Harald, Matys, Ronald, Moock, Marion, Regiert, Thomas, Maier-Borst, Wolfgang

“…Recently, we demonstrated the feasibility of combining improved tumor-to-tissue contrasts and PET imaging for immunoscintigraphic tumor localization using a…”
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Immunoscintigraphy of human mammary carcinoma xenografts using monoclonal antibodies 12H12 and BM-2 labeled with 99mTc and radioiodine by BRÜMMENDORF, T. H, KAUL, S, SCHUHMACHER, J, BAUM, R. P, MATYS, R, KLIVENYI, G, ADAMS, S, BASTERT, G

“…For immunoscintigraphic localization of human breast cancer two monoclonal antibodies (mabs) 12H12 (immunoglobulin G1) and BM-2 (immunoglobulin G3) were…”
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Uptake of Indium-111 in the Liver of Mice Following Administration of Indium-111-DTPA-Labeled Monoclonal Antibodies: Influence of Labeling Parameters, Physiologic Parameters, and Antibody Dose by Schuhmacher, Jochen, Klivenyi, Gabor, Matys, Ronald, Kirchgebner, Henning, Hauser, Harald, Maier-Borst, Wolfgang, Matzku, Siegfried

“…Liver uptake of indium-111 (111In) in mice was investigated following administration of 111In-DTPA murine monoclonal antibodies (111In-DTPA-MAbs) labeled by…”
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Labeling of monoclonal antibodies with a 67Ga-phenolic aminocarboxylic acid chelate. Part I. Chemistry and labeling technique by Schuhmacher, J, Matys, R, Hauser, H, Maier-Borst, W, Matzku, S

“…As a chelating agent for labeling antibodies (Abs) with metallic radionuclides, a propionic acid substituted ethylenediamine N,N'-di-[(o-hydroxyphenyl) acetic…”
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Antineoplastic activity of ASTA Z 7557 (INN mafosfamide) in transplanted and autochthonous experimental rodent tumors by Zeller, W J, Berger, M R, Matys, R, Schuhmacher, J

“…The antineoplastic activities of ASTA Z 7557 and cyclophosphamide (CPA) were compared in advanced transplanted AKR lymphoma by determining the optimal dose…”
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A Ga-68-Labeled Tetrabromophthalein (Ga-68 BP-IDA) for Positron Imaging of Hepatobiliary Function: Concise Communication by Schuhmacher, Jochen, Matys, Ronald, Hauser, Harald, Clorius, John H, Maier-Borst, Wolfgang

“…We describe the chemical synthesis of an iminodiacetic-acid-substituted tetrabromo-o-cresolphthalein (BP-IDA), which complexes Ga-68 tightly. The liver uptake,…”
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A bifunctional HBED-derivative for labeling of antibodies with 67Ga, 111In and 59Fe. Comparative biodistribution with 111In-DPTA and 131I-labeled antibodies in mice bearing antibody internalizing and non-internalizing tumors by Schuhmacher, J, Klivényi, G, Hull, W E, Matys, R, Hauser, H, Kalthoff, H, Schmiegel, W H, Maier-Borst, W, Matzku, S

“…To investigate whether bifunctional ligands containing chelating structures other than EDTA and DTPA and metallic radiotracers other than 111In will reduce the…”
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