Search Results - "Matyas, Jessica J."
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Function and Mechanisms of Truncated BDNF Receptor TrkB.T1 in Neuropathic Pain
Published in Cells (Basel, Switzerland) (11-05-2020)“…Brain-derived neurotrophic factor (BDNF), a major focus for regenerative therapeutics, has been lauded for its pro-survival characteristics and involvement in…”
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Dissecting Genetic Mechanisms of Differential Locomotion, Depression, and Allodynia after Spinal Cord Injury in Three Mouse Strains
Published in Cells (Basel, Switzerland) (01-05-2024)“…Strain differences have been reported for motor behaviors, and only a subset of spinal cord injury (SCI) patients develop neuropathic pain, implicating genetic…”
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Inhibition of NOX2 signaling limits pain-related behavior and improves motor function in male mice after spinal cord injury: Participation of IL-10/miR-155 pathways
Published in Brain, behavior, and immunity (01-08-2019)“…•Inhibition of NOX2 alleviates post-SCI pain-related behavior and motor dysfunction.•NOX2 deficiency alters microglial/macrophage activation.•NOX2−/− reduces…”
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Delayed microglial depletion after spinal cord injury reduces chronic inflammation and neurodegeneration in the brain and improves neurological recovery in male mice
Published in Theranostics (01-01-2020)“…Neuropsychological deficits, including impairments in learning and memory, occur after spinal cord injury (SCI). In experimental SCI models, we and others have…”
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Truncated TrkB.T1-Mediated Astrocyte Dysfunction Contributes to Impaired Motor Function and Neuropathic Pain after Spinal Cord Injury
Published in The Journal of neuroscience (05-04-2017)“…Following spinal cord injury (SCI), astrocytes demonstrate long-lasting reactive changes, which are associated with the persistence of neuropathic pain and…”
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Effects of Bone-Marrow–Derived MSC Transplantation on Functional Recovery in a Rat Model of Spinal Cord Injury: Comparisons of Transplant Locations and Cell Concentrations
Published in Cell transplantation (01-08-2017)“…Spinal cord injury (SCI) is a widely disabling condition, constraining those affected by it to wheelchairs and requiring intense daily care and assistance…”
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Cell cycle inhibition reduces inflammatory responses, neuronal loss, and cognitive deficits induced by hypobaria exposure following traumatic brain injury
Published in Journal of neuroinflammation (01-12-2016)“…Traumatic brain injury (TBI) patients in military settings can be exposed to prolonged periods of hypobaria (HB) during aeromedical evacuation. Hypobaric…”
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Effects of Bone-Marrow–Derived MSC Transplantation on Functional Recovery in a Rat Model of Spinal Cord Injury
Published in Cell transplantation (01-08-2017)“…Spinal cord injury (SCI) is a widely disabling condition, constraining those affected by it to wheelchairs and requiring intense daily care and assistance…”
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