Search Results - "Matwyshyn, G A"
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Dizocilpine (MK-801) blocks tolerance to the analgesic but not to the hyperthermic effect of morphine in the rat
Published in Pharmacology (01-12-1993)“…The effect of dizocilpine (MK-801), an N-methyl-D-aspartate receptor antagonist, on the development of tolerance to the analgesic and hyperthermic effects of…”
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2
Activation of signal transduction kinases by tamoxifen
Published in Pharmaceutical research (01-02-1997)“…To study the signal transduction mechanisms of tamoxifen via the activation of MAPKs, JNK and ERK in order to understand its regulation of gene expression. The…”
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3
Transcription regulation of rat glutathione S-transferase Ya subunit gene expression by chemopreventive agents
Published in Pharmaceutical research (01-07-1996)“…To study the transcription regulation of rat glutathione S-transferase Ya (rGSTya) subunit gene expression by chemopreventive agents. The effects of…”
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4
Regulation of gene expression of various Phase I and Phase II drug-metabolizing enzymes by tamoxifen in rat liver
Published in Biochemical pharmacology (22-11-1996)“…The objective of the present investigation was to evaluate the effect of tamoxifen (TAM) on the gene expression of different phase I and phase II…”
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5
beta-Endorphin-like immunoreactivity in discrete brain regions, spinal cord, pituitary gland and peripheral tissues of U-50,488H-tolerant and -abstinent rats
Published in The Journal of pharmacology and experimental therapeutics (01-02-1994)“…The effect was determined of trans-3,4-dichloro-N-methyl-N-[2-(1-pyrrolidinyl)cyclohexyl]benzene- acetamide methane sulfonate (U-50,488H), a kappa opioid…”
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6
cDNA cloning of the mouse bilirubin/phenol family of UDP-glucuronosyltransferase (mUGTbr2-like)
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7
Brain and spinal cord kappa opiate receptors and pharmacological responses to U-50,488H in rats of differing ages
Published in Pharmacology, biochemistry and behavior (01-05-1994)“…The analgesic and hypothermic responses to U-50,488H (25 mg/kg IP), a kappa opiate receptor agonist, were determined in male Sprague-Dawley rats aged 4, 8, and…”
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8
The effect of U-50,488H tolerance-dependence and abstinence on the levels of dynorphin (1-13) in brain regions, spinal cord, pituitary gland and peripheral tissues of the rat
Published in Brain research (08-01-1993)“…Male Sprague-Dawley rats were rendered tolerant to and physically dependent on U-50,488H, a kappa-opiate agonist, by injecting 25 mg/kg of the drug…”
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9
Opioid peptides in pituitary gland, brain regions and peripheral tissues of spontaneously hypertensive and Wistar-Kyoto normotensive rats
Published in Brain research (09-02-1988)“…The concentrations of beta-endorphin (beta-END), dynorphin (DYN) and methionine-enkephalin (MEK) in pituitary, brain regions, heart, kidney and adrenal of 8…”
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10
Methionine-enkephalin concentrations in discrete brain regions, spinal cord, pituitary gland and peripheral tissues of U-50,488H-tolerant and abstinent rats
Published in Pharmacology (01-04-1994)“…Effects were determined of chronic administration and withdrawal of a highly selective kappa-opioid receptor agonist, U-50,488H, on methionine-enkephalin…”
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11
Comparative effects of thyrotropin releasing hormone, MK-771 and DN-1417 on morphine abstinence syndrome
Published in Psychopharmacologia (01-01-1985)“…The effects of thyrotropin releasing hormone (TRH) were compared with two of its analogs, L-N-(2-oxopiperidine-6-yl-carbonyl)-L-histidyl-L-thiazolidine-4-carbo…”
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12
Brain and pituitary receptors for thyrotropin-releasing hormone in hypothyroid rats
Published in Pharmacology (1989)“…The effect of hypothyroidism on the thyrotropin-releasing hormone (TRH) receptors in several brain regions and pituitary of rats was determined. TRH receptors…”
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13
Comparative effects of NG-monomethyl-L-arginine and MK-801 on the abstinence syndrome in morphine-dependent mice
Published in Brain research (11-04-1994)“…The effects of NG-monomethyl-L-arginine (L-NMMA), an inhibitor of nitric oxide (NO) synthase and MK-801, an NMDA receptor antagonist on abrupt and…”
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14
Effects of acute and chronic administration of dizocilpine on the pharmacological responses to U-50,488H and brain and spinal cord kappa-opioid receptors in the rat
Published in Pharmacology (01-11-1995)“…In male Sprague-Dawley rats, acute and chronic effects of dizocilpine (MK-801), a noncompetitive antagonist of the N-methyl-D-aspartate (NMDA) receptor, were…”
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15
Effect of morphine tolerance and abstinence on the binding of [3H]naltrexone to discrete brain regions and spinal cord of the rat
Published in General pharmacology (01-03-1994)“…1. The effect of morphine tolerance and abstinence on the binding of [3H]naltrexone to discrete brain regions and spinal cord of the rat was determined. 2…”
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16
Effects of naltrexone pellet implantation on morphine tolerance and physical dependence in the rat
Published in General pharmacology (01-01-1994)“…1. The effect of naltrexone pellets containing either 10 or 30 mg of naltrexone base on the development of tolerance and physical dependence on morphine was…”
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17
The binding of 3H-(3-MeHis2) thyrotropin releasing hormone to brain membranes and temperature response to thyrotropin releasing hormone in different strains of mice
Published in Neuropharmacology (01-08-1986)“…The effect of thyrotropin releasing hormone (TRH) on the colonic temperature of five strains of mice, namely, Swiss Webster, ICR, C57 BL, BALB and DBA, was…”
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18
Influence of thyrotropin releasing hormone and histidyl-proline diketopiperazine on spontaneous locomotor activity and analgesia induced by delta 9-tetrahydrocannabinol in the mouse
Published in European journal of pharmacology (21-11-1980)“…The influence of thyrotropin releasing hormone (TRH) and its postulated metabolite histidyl-proline diketopiperazine (HPD) on sedation and analgesia produced…”
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19
Effects of Pro-Leu-Gly-NH2 and cyclo (Leu-Gly) on the binding of 3H-quinuclidinyl benzilate to striatal cholinergic muscarinic receptors
Published in Peptides (New York, N.Y. : 1980) (01-01-1986)“…The effects of Pro-Leu-Gly-NH2 (melanotropin release inhibiting factor, MIF) and its analog, cyclo (Leu-Gly) on the mouse and rat striatal cholinergic…”
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20
Brain serotonin turnover and morphine tolerance-dependence induced by multiple injections in the rat
Published in European journal of pharmacology (01-07-1977)“…Tolerance to and physical dependence on morphine in the rat was induced by injecting increasing doses of morphine sulfate (M.S.) administered i.p. twice daily…”
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