Search Results - "Matute, Juan D"
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Epithelial endoplasmic reticulum stress orchestrates a protective IgA response
Published in Science (American Association for the Advancement of Science) (01-03-2019)“…Immunoglobulin A (IgA) is the major secretory immunoglobulin isotype found at mucosal surfaces, where it regulates microbial commensalism and excludes luminal…”
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2
Intestinal epithelial cell endoplasmic reticulum stress promotes MULT1 up-regulation and NKG2D-mediated inflammation
Published in The Journal of experimental medicine (02-10-2017)“…Endoplasmic reticulum (ER) stress is commonly observed in intestinal epithelial cells (IECs) and can, if excessive, cause spontaneous intestinal inflammation…”
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3
Intelectin-1 binds and alters the localization of the mucus barrier-modifying bacterium Akkermansia muciniphila
Published in The Journal of experimental medicine (02-01-2023)“…Intelectin-1 (ITLN1) is a lectin secreted by intestinal epithelial cells (IECs) and upregulated in human ulcerative colitis (UC). We investigated how ITLN1…”
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4
Human alkaline phosphatase dephosphorylates microbial products and is elevated in preterm neonates with a history of late-onset sepsis
Published in PloS one (27-04-2017)“…A host defense function for Alkaline phosphatases (ALPs) is suggested by the contribution of intestinal ALP to detoxifying bacterial lipopolysaccharide…”
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5
Characterizing CD4 T cell differentiation in mouse small intestine using T cell transfer, lamina propria preparation, and flow cytometry
Published in STAR protocols (15-09-2023)“…Studying gene function in T cells is crucial for understanding physiology and disease pathogenesis. Here, we provide a protocol to examine the role of specific…”
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Establishment of a pediatric COVID-19 biorepository: unique considerations and opportunities for studying the impact of the COVID-19 pandemic on children
Published in BMC medical research methodology (11-09-2020)“…COVID-19, the disease caused by the highly infectious and transmissible coronavirus SARS-CoV-2, has quickly become a morbid global pandemic. Although the…”
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7
Rapid establishment of a COVID-19 perinatal biorepository: early lessons from the first 100 women enrolled
Published in BMC medical research methodology (26-08-2020)“…Collection of biospecimens is a critical first step to understanding the impact of COVID-19 on pregnant women and newborns - vulnerable populations that are…”
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Correction: Human alkaline phosphatase dephosphorylates microbial products and is elevated in preterm neonates with a history of late-onset sepsis
Published in PloS one (10-05-2018)“…[This corrects the article DOI: 10.1371/journal.pone.0175936.]…”
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9
IL-22: Immunity's bittersweet symphony
Published in The Journal of experimental medicine (06-11-2023)“…Epithelial cells play a crucial role in barrier defense. Here, Moniruzzaman et al. (2023. J. Exp. Med.https://doi.org/10.1084/jem.20230106) discovered that…”
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10
Compromised SARS-CoV-2-specific placental antibody transfer
Published in Cell (04-02-2021)“…SARS-CoV-2 infection causes more severe disease in pregnant women compared to age-matched non-pregnant women. Whether maternal infection causes changes in the…”
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11
Microbial RNAs Pressure Piezo1 to Respond
Published in Cell (06-08-2020)“…Serotonin production by enterochromaffin cells (ECs) is microbiota-dependent, but the mechanism of this is unknown. In this issue of Cell, Sugisawa et al…”
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12
The healing power of language: caring for patients with limited english proficiency and COVID-19
Published in Pediatric research (01-02-2022)Get full text
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13
Endoplasmic reticulum stress in the intestinal epithelium initiates purine metabolite synthesis and promotes Th17 cell differentiation in the gut
Published in Immunity (Cambridge, Mass.) (09-05-2023)“…Intestinal IL-17-producing T helper (Th17) cells are dependent on adherent microbes in the gut for their development. However, how microbial adherence to…”
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14
Necrotizing Enterocolitis in Neonates With Hyperinsulinemic Hypoglycemia Treated With Diazoxide
Published in Pediatrics (Evanston) (01-02-2021)“…The most common cause of persistent hypoglycemia in the neonatal period is hyperinsulinism. Severe, refractory hypoglycemia resulting from hyperinsulinism can…”
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15
Case 30-2022: A Newborn Girl with Hypoglycemia
Published in The New England journal of medicine (29-09-2022)“…A newborn girl was admitted to the neonatal ICU with prolonged hypoglycemia. At 34 weeks of gestation, an ultrasonographic survey of the fetal anatomy had…”
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16
Sterile activation of invariant natural killer T cells by ER-stressed antigen-presenting cells
Published in Proceedings of the National Academy of Sciences - PNAS (19-11-2019)“…Invariant NKT (iNKT) cells have the unique ability to shape immunity during antitumor immune responses and other forms of sterile and nonsterile inflammation…”
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17
Standardizing the Evaluation and Management of Necrotizing Enterocolitis in a Level IV NICU
Published in Pediatrics (Evanston) (01-10-2022)“…Necrotizing enterocolitis (NEC) is a severe intestinal inflammatory disease and a leading cause of morbidity and mortality in NICUs. Management of NEC is…”
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Single-cell immunophenotyping of the fetal immune response to maternal SARS-CoV-2 infection in late gestation
Published in Pediatric research (01-04-2022)“…Background During the COVID-19 pandemic, thousands of pregnant women have been infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The…”
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19
Screening for modulators of the cellular composition of gut epithelia via organoid models of intestinal stem cell differentiation
Published in Nature biomedical engineering (01-04-2022)“…The cellular composition of barrier epithelia is essential to organismal homoeostasis. In particular, within the small intestine, adult stem cells establish…”
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Activation of neutrophil respiratory burst by fungal particles requires phosphatidylinositol 3-phosphate binding to p40(phox) in humans but not in mice
Published in Blood (18-10-2012)Get full text
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