Search Results - "Matuszczyk, Iwona"

Rapamycin prevents strong phosphorylation of p53 on serine 46 and attenuates activation of the p53 pathway in A549 lung cancer cells exposed to actinomycin D by Krześniak, Małgorzata, Zajkowicz, Artur, Matuszczyk, Iwona, Rusin, Marek

“…•Actinomycin D strongly activates the p53 pathway in the A549 lung cancer cell line.•Actinomycin D promotes phosphorylation of p53 on Ser46.•Rapamycin inhibits…”
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A novel germline TP53 mutation p.Pro190Arg detected in a patient with lung and bilateral breast cancers by Krześniak, Małgorzata, Butkiewicz, Dorota, Rachtan, Jadwiga, Matuszczyk, Iwona, Grzybowska, Ewa, Rusin, Marek

“…Li-Fraumeni syndrome (LFS) is a rare genetic disease with strong predispositions to multiple early-onset neoplasms, mostly sarcomas, breast cancers, brain…”
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Influence of DNA repair gene polymorphisms on prognosis in inoperable non-small cell lung cancer patients treated with radiotherapy and platinum-based chemotherapy by Butkiewicz, Dorota, Drosik, Anna, Suwiński, Rafał, Krześniak, Małgorzata, Rusin, Marek, Kosarewicz, Agata, Rachtan, Jadwiga, Matuszczyk, Iwona, Gawkowska-Suwińska, Marzena

“…Polymorphisms in DNA repair genes may modulate not only an individual DNA repair capacity, DNA damage levels and cancer risk but also clinical outcome after…”
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Nutlin-3a, an MDM2 antagonist and p53 activator, helps to preserve the replicative potential of cancer cells treated with a genotoxic dose of resveratrol by Zajkowicz, Artur, Krześniak, Małgorzata, Matuszczyk, Iwona, Głowala-Kosińska, Magdalena, Butkiewicz, Dorota, Rusin, Marek

“…Resveratrol is a natural compound that has been intensely studied due to its role in cancer prevention and potential as an anti-cancer therapy. Its effects…”
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