Search Results - "Matuszczak, Sybilla"
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Mesenchymal stromal cells as carriers of IL-12 reduce primary and metastatic tumors of murine melanoma
Published in Scientific reports (15-09-2021)“…Due to immunosuppressive properties and confirmed tropism towards cancer cells mesenchymal stromal cells (MSC) have been used in many trials. In our study we…”
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2
M1-like macrophages change tumor blood vessels and microenvironment in murine melanoma
Published in PloS one (10-01-2018)“…Tumor-associated macrophages (TAMs) play a significant role in at least two key processes underlying neoplastic progression: angiogenesis and immune…”
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3
The effect of culture media on large-scale expansion and characteristic of adipose tissue-derived mesenchymal stromal cells
Published in Stem cell research & therapy (05-08-2019)“…Adipose tissue-derived mesenchymal stromal cells (ASCs) have been shown to exhibit some promising properties of their use in regenerative medicine as advanced…”
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4
Antitumor effect of anti-vascular therapy with STING agonist depends on the tumor microenvironment context
Published in Frontiers in oncology (15-08-2023)“…IntroductionTargeting tumor vasculature is an efficient weapon to fight against cancer; however, activation of alternative pathways to rebuild the disrupted…”
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5
The comparison of adipose-derived stromal cells (ADSCs) delivery method in a murine model of hindlimb ischemia
Published in Stem cell research & therapy (02-02-2024)“…Adipose-derived stromal cells (ADSCs) demonstrate ability to promote tissue healing and down-regulate excessive inflammation. ADSCs have been used to treat…”
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6
Brachytherapy in a Single Dose of 10Gy as an "in situ" Vaccination
Published in International journal of molecular sciences (28-06-2020)“…Radiotherapy (RT) is one of the major methods of cancer treatment. RT destroys cancer cells, but also affects the tumor microenvironment (TME). The delicate…”
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Human Cardiac Mesenchymal Stromal Cells with CD105+CD34- Phenotype Enhance the Function of Post-Infarction Heart in Mice
Published in PloS one (01-07-2016)“…The aim of the present study was to isolate mesenchymal stromal cells (MSC) with CD105+CD34- phenotype from human hearts, and to investigate their therapeutic…”
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The Effect of Radiotherapy on Cell Survival and Inflammatory Cytokine and Chemokine Secretion in a Co-Culture Model of Head and Neck Squamous Cell Carcinoma and Normal Cells
Published in Biomedicines (01-06-2023)“…Radiotherapy (RT) is one of the main treatments for head and neck squamous cell carcinomas (HNSCCs). Unfortunately, radioresistance is observed in many cases…”
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The Role of Glycyrrhizin, an Inhibitor of HMGB1 Protein, in Anticancer Therapy
Published in Archivum Immunologiae et Therapiae Experimentalis (01-10-2012)“…Certain anticancer drugs, such as the peptide CAMEL (aa sequence KWKLFKKIGAULKVL) induce necrotic type of cell death. During this process, a protein termed…”
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10
The Complex Composition of Trans-resveratrol, Quercetin, Vitamin E and Selenium Inhibits the Growth of Colorectal Carcinoma
Published in Anticancer research (01-10-2022)“…Background/Aim: Numerous studies have demonstrated an anti-cancer action of plant-derived polyphenols. Their action is mainly related to antioxidant,…”
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Combination of STING agonist with anti-vascular RGD-(KLAKLAK)2 peptide as a novel anti-tumor therapy
Published in Cancer Immunology, Immunotherapy : CII (04-06-2024)“…Immunotherapy is one of the most promising anti-cancer treatment. It involves activating the host's own immune system to eliminate cancer cells. Activation of…”
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12
Adipose tissue-derived stromal cells stimulated macrophages-endothelial cells interactions promote effective ischemic muscle neovascularization
Published in European journal of pharmacology (15-09-2020)“…Neovascularization, the process of new blood vessels formation in response to hypoxia induced signals, is an essential step during wound healing or ischemia…”
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13
The Proper Administration Sequence of Radiotherapy and Anti-Vascular Agent—DMXAA Is Essential to Inhibit the Growth of Melanoma Tumors
Published in Cancers (04-08-2021)“…Vascular disrupting agents (VDAs), such as DMXAA, effectively destroy tumor blood vessels and cause the formation of large areas of necrosis in the central…”
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14
D-K6L9 Peptide Combination with IL-12 Inhibits the Recurrence of Tumors in Mice
Published in Archivum Immunologiae et Therapiae Experimentalis (2014)“…D-K 6 L 9 peptide is bound by phosphatidylserine and induces necrosis in cancer cells. In our therapeutic experience, this peptide, when administered directly…”
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15
Human Cardiac Mesenchymal Stromal Cells with CD105.sup.+CD34.sup.- Phenotype Enhance the Function of Post-Infarction Heart in Mice
Published in PloS one (14-07-2016)“…Aims The aim of the present study was to isolate mesenchymal stromal cells (MSC) with CD105.sup.+ CD34.sup.- phenotype from human hearts, and to investigate…”
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16
Combined Tumor Cell-Based Vaccination and Interleukin-12 Gene Therapy Polarizes the Tumor Microenvironment in Mice
Published in Archivum Immunologiae et Therapiae Experimentalis (01-12-2015)“…Tumor progression depends on tumor milieu, which influences neovasculature formation and immunosuppression. Combining immunotherapy with…”
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Journal Article Book Review -
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Characteristic of c-Kit+ progenitor cells in explanted human hearts
Published in Clinical research in cardiology (01-09-2014)“…According to literature data, self-renewing, multipotent, and clonogenic cardiac c-Kit + progenitor cells occur within human myocardium. The aim of this study…”
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D-K^sub 6^L^sub 9^ Peptide Combination with IL-12 Inhibits the Recurrence of Tumors in Mice
Published in Archivum Immunologiae et Therapiae Experimentalis (01-08-2014)“…D-K^sub 6^L^sub 9^ peptide is bound by phosphatidylserine and induces necrosis in cancer cells. In our therapeutic experience, this peptide, when administered…”
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19
Mesenchymal stromal cells
Published in Postȩpy higieny i medycyny doświadczalnej (13-11-2014)“…Mesenchymal stromal cells (MSCs) have been among the most intensively studied cells in recent years. Lack of specific unique markers for these cells makes it…”
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Characteristic of c-Kit^sup +^ progenitor cells in explanted human hearts
Published in Clinical research in cardiology (01-09-2014)“…According to literature data, self-renewing, multipotent, and clonogenic cardiac c-Kit^sup +^ progenitor cells occur within human myocardium. The aim of this…”
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