Search Results - "Matuszak, Ryan P."

Design, Synthesis, and Biological Investigation of Thailanstatin A and Spliceostatin D Analogues Containing Tetrahydropyran, Tetrahydrooxazine, and Fluorinated Structural Motifs by Nicolaou, K. C, Rekula, Santhosh Reddy, Kumar, S. Mothish, Podilapu, Ananda Rao, Matuszak, Ryan P, Jung, Paul M, Lam, Lloyd T, Phillips, Andrew C, Lyssikatos, Joseph, Munneke, Stefan, Gu, Christine, Sarvaiya, Hetal, Sandoval, Joseph, Hammond, Mikhail, Aujay, Monette, Purcell, James W, Reilly, Regina M, Gavrilyuk, Julia

“…Thailanstatin A and spliceostatin D, two naturally occurring molecules endowed with potent antitumor activities by virtue of their ability to bind and inhibit…”
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Abstract 6311: ABBV-400: An ADC delivering a novel topoisomerase 1 inhibitor to c-Met-positive solid tumors by Reilly, Regina M., Ji, Cheng, Matuszak, Ryan P., Anderson, Mark G., Tucker, Lora, Klunder, Nadezda, Lazo, Adelyn L., Boghaert, Erwin R., Pysz, Marybeth A., D’Souza, Aloma, Kreckler, Laura, Bruncko, Milan, Mills, Brittney J., Ravn, Matthew, Doherty, George, Freise, Kevin J., Phillips, Andrew C.

“…Antibody-drug conjugate (ADC) technology is founded on the premise that antigen-mediated payload delivery selectively targets tumor cells and spares normal…”
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