Search Results - "Matusik, RJ"

Molecular Alterations in Primary Prostate Cancer after Androgen Ablation Therapy by BEST, Carolyn J. M, GILLESPIE, John W, GONZALEZ, Sergio, VELASCO, Alfredo, LINEHAN, W. Marston, MATUSIK, Robert J, PRICE, Douglas K, FIGG, William D, EMMERT-BUCK, Michael R, CHUAQUI, Rodrigo F, YAJUN YI, CHANDRAMOULI, Gadisetti V. R, PERLMUTTER, Mark A, GATHRIGHT, Yvonne, ERICKSON, Heidi S, GEORGEVICH, Lauren, TANGREA, Michael A, DURAY, Paul H

“…Purpose: After an initial response to androgen ablation, most prostate tumors recur, ultimately progressing to highly aggressive androgen-independent cancer…”
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SKP2 loss destabilizes EZH2 by promoting TRAF6-mediated ubiquitination to suppress prostate cancer by Lu, W, Liu, S, Li, B, Xie, Y, Izban, M G, Ballard, B R, Sathyanarayana, S A, Adunyah, S E, Matusik, R J, Chen, Z

“…EZH2 is crucial for the progression of prostate cancer (PCa) and castration-resistant prostate cancer (CRPC) through upregulation and activation of progenitor…”
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Hepsin promotes prostate cancer progression and metastasis by Klezovitch, Olga, Chevillet, John, Mirosevich, Janni, Roberts, Richard L., Matusik, Robert J., Vasioukhin, Valeri

“…The majority of cancer-related deaths are associated with metastasis; however, little is known about the mechanisms of this process. Hepsin is a cell surface…”
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The Role of Hepatocyte Nuclear Factor-3α (Forkhead Box A1) and Androgen Receptor in Transcriptional Regulation of Prostatic Genes by Gao, Nan, Zhang, Jianfeng, Rao, Mira A, Case, Thomas C, Mirosevich, Janni, Wang, Yongqing, Jin, Renjie, Gupta, Aparna, Rennie, Paul S, Matusik, Robert J

“…Androgens and mesenchymal factors are essential extracellular signals for the development as well as the functional activity of the prostate epithelium. Little…”
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A small composite probasin promoter confers high levels of prostate-specific gene expression through regulation by androgens and glucocorticoids in vitro and in vivo by Zhang, J, Thomas, T Z, Kasper, S, Matusik, R J

“…Transient transfection studies have shown that the probasin (PB) promoter confers androgen selectivity over other steroid hormones, and transgenic animal…”
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Forkhead box A1 regulates prostate ductal morphogenesis and promotes epithelial cell maturation by Gao, Nan, Ishii, Kenichiro, Mirosevich, Janni, Kuwajima, Satoru, Oppenheimer, Stacey R, Roberts, Richard L, Jiang, Ming, Yu, Xiuping, Shappell, Scott B, Caprioli, Richard M, Stoffel, Markus, Hayward, Simon W, Matusik, Robert J

“…We have previously shown that a forkhead transcription factor Foxa1 interacts with androgen signaling and controls prostate differentiated response. Here, we…”
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Foxa1 and Foxa2 Interact with the Androgen Receptor to Regulate Prostate and Epididymal Genes Differentially by YU, XIUPING, GUPTA, APARNA, WANG, YONGQING, SUZUKI, KICHIYA, MIROSEVICH, JANNI, ORGEBIN-CRIST, MARIE-CLAIRE, MATUSIK, ROBERT J.

“…: Previous studies from our group have shown that Foxa1 is expressed in the prostate and interacts with the androgen receptor (AR) to regulate…”
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A probasin-large T antigen transgenic mouse line develops prostate adenocarcinoma and neuroendocrine carcinoma with metastatic potential by Masumori, N, Thomas, T Z, Chaurand, P, Case, T, Paul, M, Kasper, S, Caprioli, R M, Tsukamoto, T, Shappell, S B, Matusik, R J

“…Neuroendocrine (NE) cells may be involved not only in growth and differentiation of the normal prostate but also in carcinogenesis and progression of prostate…”
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NE-10 neuroendocrine cancer promotes the LNCaP xenograft growth in castrated mice by REN JIE JIN, YONGQING WANG, MASUMORI, Naoya, ISHII, Kenichiro, TSUKAMOTO, Taiji, SHAPPELL, Scott B, HAYWARD, Simon W, KASPER, Susan, MATUSIK, Robert J

“…Increases in neuroendocrine (NE) cells and their secretory products are closely correlated with tumor progression and androgen-independent prostate cancer…”
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Selective activation of the probasin androgen-responsive region by steroid hormones by Kasper, S, Rennie, PS, Bruchovsky, N, Lin, L, Cheng, H, Snoek, R, Dahlman-Wright, K, Gustafsson, JA, Shiu, RP, Sheppard, PC, Matusik, RJ

“…Glucocorticoid and androgen receptors have been shown to function through the same palindromic glucocorticoid response element (GRE) and yet have differential…”
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Prostate Cancer in a Transgenic Mouse by Greenberg, N. M., DeMayo, F., Finegold, M. J., Medina, D., Tilley, W. D., Aspinall, J. O., Cunha, G. R., Donjacour, A. A., Matusik, R. J., Rosen, J. M.

“…Progress toward understanding the biology of prostate cancer has been slow due to the few animal research models available to study the spectrum of this…”
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15S-Hydroxyeicosatetraenoic acid activates peroxisome proliferator-activated receptor γ and inhibits proliferation in PC3 prostate carcinoma cells by SHAPPELL, Scott B, GUPTA, Rajnish A, MATUSIK, Robert J, BRASH, Alan R, DUBOIS, Raymond N, MANNING, Suzanne, WHITEHEAD, Robert, BOEGLIN, William E, SCHNEIDER, Claus, CASE, Tom, PRICE, James, JACK, Gregory S, WHEELER, Thomas M

“…15-Lipoxygenase (15-LOX)-2 is expressed in benign prostate secretory cells and benign prostate produces 15S-hydroxyeicosatetraenoic acid (15S-HETE) from…”
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Molecular evolution of epididymal lipocalin genes localized on mouse chromosome 2 by Suzuki, Kichiya, Lareyre, Jean-Jacques, Sánchez, Diego, Gutierrez, Gabriel, Araki, Yoshihiko, Matusik, Robert J., Orgebin-Crist, Marie-Claire

“…We previously identified two murine secretory proteins, mE-RABP(Lcn5) and mEP17(Lcn8), belonging to the lipocalin family and specifically expressed in the…”
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Murine androgen-independent neuroendocrine carcinoma promotes metastasis of human prostate cancer cell line LNCaP by Uchida, Kohsuke, Masumori, Naoya, Takahashi, Atsushi, Itoh, Naoki, Kato, Kazunori, Matusik, Robert J., Tsukamoto, Taiji

“…BACKGROUND Although neuroendocrine (NE) cells in prostate cancer have been speculated to accelerate the growth and progression of surrounding cancer cells, the…”
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The Loss of TGF-β Signaling Promotes Prostate Cancer Metastasis by Tu, William H., Thomas, Tania Z., Masumori, Naoya, Bhowmick, Neil A., Gorska, Agnieszka E., Shyr, Yu, Kasper, Susan, Case, Tom, Roberts, Richard L., Shappell, Scott B., Moses, Harold L., Matusik, Robert J.

“…In breast and colon cancers, transforming growth factor (TGIF)-β signaling initially has an antineoplastic effect, inhibiting tumor growth, but eventually…”
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Elevated expression of 12/15-lipoxygenase and cyclooxygenase-2 in a transgenic mouse model of prostate carcinoma by SHAPPELL, Scott B, OLSON, Sandra J, SHOOK, M. Frances, THOMAS, Tania Z, FUNK, Colin D, BRASH, Alan R, MATUSIK, Robert J, HANNAH, S. Erin, MANNING, Suzanne, ROBERTS, Richard L, MASUMORI, Naoya, JISAKA, Mitsuo, BOEGLIN, William E, VADER, Virginia, DAVE, Dhiren S

“…Changes in expression of arachidonic acid (AA) metabolizing enzymes are implicated in the development and progression of human prostate carcinoma (Pca)…”
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Mutations at the boundary of the hinge and ligand binding domain of the androgen receptor confer increased transactivation function by Buchanan, G, Yang, M, Harris, J M, Nahm, H S, Han, G, Moore, N, Bentel, J M, Matusik, R J, Horsfall, D J, Marshall, V R, Greenberg, N M, Tilley, W D

“…The androgen receptor (AR), a member of the steroid receptor superfamily of nuclear transcription factors, mediates androgen signaling in diverse target…”
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Fibroblast growth factor 8 isoform b overexpression in prostate epithelium: A new mouse model for prostatic intraepithelial neoplasia by ZHIGANG SONG, XIANTUO WU, POWELL, William C, CARDIFF, Robert D, COHEN, Michael B, TIN, Robert T, MATUSIK, Robert J, MILLER, Gary J, ROY-BURMAN, Pradip

“…Fibroblast growth factor 8 isoform b (FGF8b), a mitogenic and transforming polypeptide, was demonstrated to be naturally up-regulated in prostatic premalignant…”
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Adenovirus-mediated tissue-targeted expression of a caspase-9-based artificial death switch for the treatment of prostate cancer by XIAOMING XIE, XIUQIN ZHAO, YUANFANG LIU, JIANFENG ZHANG, MATUSIK, Robert J, SLAWIN, Kevin M, SPENCER, David M

“…Clinical experience with suicide gene therapy for prostate cancer using first-generation approaches has provided a basis for developing improved strategies…”
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Tissue-Specific Transcriptional Targeting of a Replication-Competent Retroviral Vector by Logg, Christopher R, Logg, Aki, Matusik, Robert J, Bochner, Bernard H, Kasahara, Noriyuki

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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