Search Results - "Matucci, Tommaso"
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Pretomanid for tuberculosis treatment: an update for clinical purposes
Published in Current research in pharmacology and drug discovery (2022)“…Coronavirus disease (COVID-19) pandemic determined a 10 years-set back in tuberculosis (TB) control programs. Recent advances in available therapies may help…”
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Infectious Diseases in Internationally Adopted Children and Intercountry Discrepancies Among Screening Protocols, A Narrative Review
Published in Frontiers in pediatrics (07-11-2019)“…Internationally adopted children (IAC) require thorough health assessments at time of arrival in the host country. As these children are at higher risk for…”
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Treatment of latent tuberculosis infection in incarcerated people: a systematic review
Published in Clinical microbiology and infection (01-06-2023)“…The estimated number of people deprived of liberty is increasing, with 11.55 million incarcerated globally in 2021. Transmission of Mycobacterium tuberculosis…”
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Treating children with tuberculosis: new weapons for an old enemy
Published in Journal of chemotherapy (Florence) (04-07-2019)“…Tuberculosis has risen to worldwide attention due to its widespread diffusion and overall impact on health and life expectancy. Despite being historically…”
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Rare variants in Toll-like receptor 7 results in functional impairment and downregulation of cytokine-mediated signaling in COVID-19 patients
Published in Genes and immunity (01-02-2022)“…Toll-like receptors (TLR) are crucial components in the initiation of innate immune responses to a variety of pathogens, triggering the production of…”
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Use of Second-line Medications and Treatment Outcomes in Children With Tuberculosis in a Single Center From 2007 to 2018
Published in The Pediatric infectious disease journal (01-10-2019)“…BACKGROUND:The incidence of drug-resistant forms of tuberculosis (DR-TB) and the number of children treated with second-line drugs (SLDs) are increasing…”
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Risk of SARS-CoV-2 infection and severe COVID-19 in hematological patients who received or not pre-exposure prophylaxis with tixagevimab/cilgavimab: a target trial emulation
Published in Leukemia & lymphoma (01-10-2024)“…We emulated a hypothetical target trial in which hematological subjects cared at the University Hospital of Pisa (Italy) received or not SARS-CoV-2 prophylaxis…”
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Efficacy and Safety of Nirmatrelvir/Ritonavir, Molnupiravir, and Remdesivir in a Real-World Cohort of Outpatients with COVID-19 at High Risk of Progression: The PISA Outpatient Clinic Experience
Published in Infectious diseases and therapy (01-01-2023)“…Introduction Different antivirals are available for the treatment of outpatients with COVID-19. Our aim was to describe a real-world experience of outpatient…”
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Common, low-frequency, rare, and ultra-rare coding variants contribute to COVID-19 severity
Published in Human genetics (01-01-2022)“…The combined impact of common and rare exonic variants in COVID-19 host genetics is currently insufficiently understood. Here, common and rare variants from…”
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A genome-wide association study for survival from a multi-centre European study identified variants associated with COVID-19 risk of death
Published in Scientific reports (06-02-2024)“…The clinical manifestations of SARS-CoV-2 infection vary widely among patients, from asymptomatic to life-threatening. Host genetics is one of the factors that…”
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Ultra-rare RTEL1 gene variants associate with acute severity of COVID-19 and evolution to pulmonary fibrosis as a specific long COVID disorder
Published in Respiratory research (16-06-2023)“…Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) is a novel coronavirus that caused an ongoing pandemic of a pathology termed Coronavirus Disease…”
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Combined capillary-venous-lymphatic malformations without overgrowth in patients with Klippel-Trénaunay syndrome
Published in Journal of vascular surgery. Venous and lymphatic disorders (New York, NY) (01-03-2018)“…Klippel-Trénaunay syndrome (KTS) is described in the literature as a complex syndrome characterized by various combinations of capillary, venous, and lymphatic…”
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Uncommon Haemorrhagic Cystitis of Infectious Origin: A Narrative Review for Urologists
Published in Research and reports in urology (01-01-2023)“…Haemorrhagic cystitis may be due to different etiologies with infectious diseases representing an insidious cause to diagnose. The aim of this narrative review…”
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An explainable model of host genetic interactions linked to COVID-19 severity
Published in Communications biology (26-10-2022)“…We employed a multifaceted computational strategy to identify the genetic factors contributing to increased risk of severe COVID-19 infection from a Whole…”
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