Search Results - "Mattila, Polly E."

Loss of CREBRF Reduces Anxiety-like Behaviors and Circulating Glucocorticoids in Male and Female Mice by Frahm, Krystle A, Williams, Akeem A, Wood, Ashlee N, Ewing, Michael C, Mattila, Polly E, Chuan, Byron W, Guo, Lanping, Shah, Faraaz A, O’Donnell, Christopher P, Lu, Ray, DeFranco, Donald B

“…Abstract Glucocorticoid signaling controls many key biological functions ranging from stress responses to affective states. The putative transcriptional…”
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Taking the Scenic Route: Biosynthetic Traffic to the Plasma Membrane in Polarized Epithelial Cells by Fölsch, Heike, Mattila, Polly E, Weisz, Ora A

“…The maintenance of epithelial cell function requires the establishment and continuous renewal of differentiated apical and basolateral plasma membrane domains…”
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A murine model of the human CREBRFR457Q obesity-risk variant does not influence energy or glucose homeostasis in response to nutritional stress by Kanshana, Jitendra S, Mattila, Polly E, Ewing, Michael C, Wood, Ashlee N, Schoiswohl, Gabriele, Meyer, Anna C, Kowalski, Aneta, Rosenthal, Samantha L, Gingras, Sebastien, Kaufman, Brett A, Lu, Ray, Weeks, Daniel E, McGarvey, Stephen T, Minster, Ryan L, Hawley, Nicola L, Kershaw, Erin E

“…Obesity and diabetes have strong heritable components, yet the genetic contributions to these diseases remain largely unexplained. In humans, a missense…”
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Rab11a-positive compartments in proximal tubule cells sort fluid-phase and membrane cargo by Mattila, Polly E, Raghavan, Venkatesan, Rbaibi, Youssef, Baty, Catherine J, Weisz, Ora A

“…The proximal tubule (PT) reabsorbs the majority of sodium, bicarbonate, and chloride ions, phosphate, glucose, water, and plasma proteins from the glomerular…”
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Neutrophil adhesion to E-selectin under shear promotes the redistribution and co-clustering of ADAM17 and its proteolytic substrate L-selectin by Schaff, Ulrich, Mattila, Polly E., Simon, Scott I., Walcheck, Bruce

“…E‐selectin is expressed by the vascular endothelium and binds flowing neutrophils in the blood to facilitate their recruitment into the underlying tissue at…”
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Multiple Biosynthetic Trafficking Routes for Apically Secreted Proteins in MDCK Cells by Mattila, Polly E., Youker, Robert T., Mo, Di, Bruns, Jennifer R., Cresawn, Kerry O., Hughey, Rebecca P., Ihrke, Gudrun, Weisz, Ora A.

“…Many newly synthesized membrane proteins traverse endocytic intermediates en route to the surface in polarized epithelial cells; however, the biosynthetic…”
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Dectin-1 Fc Targeting of Aspergillus fumigatus Beta-Glucans Augments Innate Defense against Invasive Pulmonary Aspergillosis by MATTILA, Polly E, METZ, Allison E, RAPAKA, Rekha R, BAUER, Lynne D, STEELE, Chad

“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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ADAM17 activity during human neutrophil activation and apoptosis by Walcheck, Bruce, Herrera, Amy H., Hill, Catherine St, Mattila, Polly E., Whitney, Adeline R., DeLeo, Frank R.

“…Substrates of the metalloprotease ADAM17 (also known as TNF‐α converting enzyme or TACE) undergo ectodomain shedding and include various inflammatory…”
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Core-glycosylated Mucin-like Repeats from MUC1 Are an Apical Targeting Signal by Kinlough, Carol L., Poland, Paul A., Gendler, Sandra J., Mattila, Polly E., Mo, Di, Weisz, Ora A., Hughey, Rebecca P.

“…MUC1 is efficiently delivered to the apical surface of polarized Madin-Darby canine kidney (MDCK) cells by transit through apical recycling endosomes, a route…”
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MUC1 traverses apical recycling endosomes along the biosynthetic pathway in polarized MDCK cells by Mattila, Polly E, Kinlough, Carol L, Bruns, Jennifer R, Weisz, Ora A, Hughey, Rebecca P

“…MUC1 is a heavily glycosylated transmembrane protein localized at the apical surface of polarized epithelial cells. Here, we examined the biosynthetic route of…”
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Cytoskeletal interactions regulate inducible L-selectin clustering by Mattila, Polly E, Green, Chad E, Schaff, Ulrich, Simon, Scott I, Walcheck, Bruce

“…L-selectin (CD62L) amplifies neutrophil capture within the microvasculature at sites of inflammation. Activation by G protein-coupled stimuli or through…”
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The monoclonal antibody CHO-131 binds to a core 2 O-glycan terminated with sialyl-Lewis x, which is a functional glycan ligand for P-selectin by Walcheck, Bruce, Leppanen, Anne, Cummings, Richard D., Knibbs, Randall N., Stoolman, Lloyd M., Alexander, Shelia R., Mattila, Polly E., McEver, Rodger P.

“…Core 2 O-glycans terminated with sialyl-Lewis x (sLeX) are functionally important oligosaccharides that endow particular macromolecules with high-affinity…”
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A murine model of the human CREBRF.sup.R457Q obesity-risk variant does not influence energy or glucose homeostasis in response to nutritional stress by Kanshana, Jitendra S, Mattila, Polly E, Ewing, Michael C, Wood, Ashlee N, Schoiswohl, Gabriele, Meyer, Anna C, Kowalski, Aneta, Rosenthal, Samantha L, Gingras, Sebastien, Kaufman, Brett A, Lu, Ray, Weeks, Daniel E, McGarvey, Stephen T, Minster, Ryan L, Hawley, Nicola L, Kershaw, Erin E

“…Obesity and diabetes have strong heritable components, yet the genetic contributions to these diseases remain largely unexplained. In humans, a missense…”
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Role of Rab11a Positive Compartments in Endocytic Traffic in Primary Proximal Tubule Cells by Raghavan, Venkatesan, Mattila, Polly E., Rbaibi, Youssef, Weisz, Ora A.

“…Abstract only The proximal tubule (PT) reabsorbs ~ 70% of sodium, bicarbonate, chloride ions, phosphate, glucose, water, and the majority of the plasma…”
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Taking the scenic route: Biosynthetic traffic to the plasma membrane in polarized epithelial cells by Fölsch, Heike, Mattila, Polly E., Weisz, Ora A.

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A soluble Dectin-1 Fc fusion protein enhances innate immunity against invasive pulmonary aspergillosis (51.8) by Mattila, Polly E, Metz, Allison E, Repaka, Rekha R, Steele, Chad

“…The Dectin-1 beta-glucan receptor is essential for alveolar macrophage (AM)-mediated defense against Aspergillus fumigatus. Increased incidence of invasive…”
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