Search Results - "Mattila, Joonatan"

Analysis of thymic generation of shared T‐cell receptor α repertoire associated with recognition of tumor antigens shows no preference for neoantigens over wild‐type antigens by Mattila, Joonatan, Sormunen, Silja, Heikkilä, Nelli, Mattila, Ilkka P., Saramäki, Jari, Arstila, T. Petteri

“…Background The number of mutations in cancer cells is an important predictor of a positive response to cancer immunotherapy. It has been suggested that the…”
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Common gamma chain cytokines promote regulatory T cell development and survival at the CD4+ CD8+ stage in the human thymus by Vanhanen, Reetta, Tuulasvaara, Anni, Mattila, Joonatan, Pätilä, Tommi, Arstila, T. Petteri

“…Thymic commitment of human FOXP3+ regulatory T cells begins at the double‐positive (DP) CD4+ CD8+ stage. In the current study, we show that interleukin‐2…”
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Generation of self-reactive, shared T-cell receptor α chains in the human thymus by Heikkilä, Nelli, Sormunen, Silja, Mattila, Joonatan, Härkönen, Taina, Knip, Mikael, Ihantola, Emmi-Leena, Kinnunen, Tuure, Mattila, Ilkka P., Saramäki, Jari, Arstila, T. Petteri

“…The T-cell receptor (TCR) repertoire is generated in a semistochastic process of gene recombination and pairing of TCRα to TCRβ chains with the estimated total…”
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Common gamma chain cytokines promote regulatory T cell development and survival at the CD 4 +   CD 8 + stage in the human thymus by Vanhanen, Reetta, Tuulasvaara, Anni, Mattila, Joonatan, Pätilä, Tommi, Arstila, T. Petteri

“…Abstract Thymic commitment of human FOXP 3 + regulatory T cells begins at the double‐positive ( DP ) CD 4 +   CD 8 + stage. In the current study, we show that…”
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