Search Results - "Mattie, D. R."

Toxicity and human health assessment of an alcohol-to-jet (ATJ) synthetic kerosene developed under an international agreement with Sweden by Mattie, D.R., Wong, B.A., Mumy, K.L., McInturf, S.M., Shafer, L.M., Allen, R., Edwards, J.T., Sibomana, I., Sterner, T.R.

“…Alcohol-to-jet (ATJ) Synthetic Kerosene with Aromatics (SKA) fuels are produced by dehydration and refining of alcohol feed stocks. ATJ SKA fuel known as SB-8…”
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Subchronic Jp-8 Jet Fuel Exposure Enhances Vulnerability To Noise-Induced Hearing Loss In Rats by Fechter, L. D., Fisher, J. W., Chapman, G. D., Mokashi, V. P., Ortiz, P. A., Reboulet, J. E., Stubbs, J. E., Lear, A. M., McInturf, S. M., Prues, S. L., Gearhart, C. A., Fulton, S., Mattie, D. R.

“…Both laboratory and epidemiological studies published over the past two decades have identified the risk of excess hearing loss when specific chemical…”
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Sensitive high-performance liquid chromatography method for the determination of low levels of perchlorate in biological samples by Narayanan, L, Buttler, G.W, Yu, K.O, Mattie, D.R, Fisher, J.W

“…A rapid and sensitive high-performance liquid chromatography (HPLC) method was developed to detect perchlorate in tissues of male and female rats, both…”
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A 90-day continuous vapor inhalation toxicity study of JP-8 jet fuel followed by 20 or 21 months of recovery in Fischer 344 rats and C57BL/6 mice by Mattie, D R, Alden, C L, Newell, T K, Gaworski, C L, Flemming, C D

“…The kerosene-type jet fuel, JP-8, consists of a complex mixture of aliphatic and aromatic hydrocarbons. Because of the utility of JP-8, studies have been…”
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Predicting Age-Appropriate Pharmacokinetics of Six Volatile Organic Compounds in the Rat Utilizing Physiologically Based Pharmacokinetic Modeling by Rodriguez, Chester E., Mahle, Deirdre A., Gearhart, Jeff M., Mattie, David R., Lipscomb, John C., Cook, Robert S., Barton, Hugh A.

“…The capability of physiologically based pharmacokinetic models to incorporate age-appropriate physiological and chemical-specific parameters was utilized to…”
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Dermal absorption of neat and aqueous volatile organic chemicals in the Fischer 344 rat by Morgan, D L, Cooper, S W, Carlock, D L, Sykora, J J, Sutton, B, Mattie, D R, McDougal, J N

“…Quantification of dermal absorption of volatile organic chemicals (VOCs) from aqueous solutions is required to understand the potential health hazards…”
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An overview of the risk assessment of hazardous materials and the role of toxicology by Mattie, D R

“…The chemical risk assessment process and the need for health-based approaches to identify and characterize potential hazardous substances will be discussed…”
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A 90-day drinking water toxicity study in rats of the environmental contaminant ammonium perchlorate by SIGLIN, Joseph C, MATTIE, David R, DODD, Darol E, HILDEBRANDT, Paul K, BAKER, William H

“…Perchlorate (ClO(4)(-)), the dissociated anion of perchlorate salts such as ammonium, potassium, and sodium perchlorate, has been recently recognized as a…”
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A REVIEW OF THE NEUROTOXICITY RISK OF SELECTED HYDROCARBON FUELS by Ritchie, G D, Still, K R, Alexander, W K, Nordholm, A F, Wilson, C L, Rossi, 3rd, J, Mattie, D R

“…Over 1.3 million civilian and military personnel are occupationally exposed to hydrocarbon fuels, emphasizing gasoline, jet fuel, diesel fuel, or kerosene…”
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The metabolism of n-nonane in male Fischer 344 rats by Serve', M.Paul, Bombick, D.D., Baughman, Todd M., Jarnot, Bruce M., Ketcha, Marcia, Mattie, David R.

“…The urinary metabolites of n-nonane in male Fischer 344 rats, after administering the hydrocarbon by gavage, included γ-valerolactone, δ-hexanolactone,…”
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Program development in military toxicology laboratories by Mattie, David R., Martin, Lana S., Childress, Terry A.

“…Military toxicology evolved from needs identified during the World Wars. The Army, Navy and Air Force developed toxicological capabilities in response to their…”
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Lack of detectable metabolism for solubilized 2,3,4-trimethylpentane by rat kidney proximal tubules by DelRaso, N J, Mattie, D R, Godin, C S

“…Primary proximal tubule suspension cultures exposed to solubilized 2,3,4-trimethylpentane (2,3,4-TMP) resulted in a linear dose response, as determined by…”
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In Vitro Toxicity of Solubilized 2,3,4-Trimethylpentane I. Cytotoxicity and Metabolism of TMP Using Primary Hepatocytes by Delraso, N. J., Mattie, D. R., Godin, C. S.

“…Primary rat hepatocyte suspension cultures (∼2 × 10⁶ cells) exposed to solubilized 2,3,4-trimethylpentane at concentrations ranging from 7.9 to 31.5 mM under…”
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The comparative toxicity of operational Air Force hydraulic fluids by Mattie, D R, Hoeflich, T J, Jones, C E, Horton, M L, Whitmire, R E, Godin, C S, Flemming, C D, Andersen, M E

“…The subchronic (26 day) oral toxicities of two AF hydraulic fluids (MIL-H-5606 [H5], MIL-H-83282 [H8]), a commercial phosphate ester (PE), and two candidate…”
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Effects of short-term oral dosing of polychlorotrifluoroethylene (polyCTFE) on the rhesus monkey by Jones, C E, Ballinger, M B, Mattie, D R, DelRaso, N J, Seckel, C, Vinegar, A

“…Polychlorotrifluoroethylene (polyCTFE--primarily oligomers with 3-4 monomer units), a non-flammable hydraulic fluid for aircraft, was given daily for 15 days…”
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The cytopathologic effects of specific aromatic hydrocarbons by Norton, WN, Mattie, DR, Kearns, CL

“…A heterogeneous mixture of the aromatic hydrocarbons benzene, toluene, and xylene is capable of inducing cellular lesions among selected organs of the fat-head…”
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Occupational exposure to hydrazines: treatment of acute central nervous system toxicity by Zelnick, Sanford D, Mattie, David R, Stepaniak, Philip C

“…Exposure to hydrazine and hydrazines' alkylated derivatives is an important occupational health issue, which will increase in significance as space…”
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Developmental Toxicity of JP‐8 Jet Fuel in the Rat by Cooper, James R., Mattie, David R.

“…JP‐8 aviation fuel is being phased in as a replacement for both JP‐4 and JP‐5 jet fuels presently in use by the Air Force and Navy, respectively. At the…”
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Lysosomal changes in renal proximal tubular epithelial cells of male Sprague Dawley rats following decalin exposure by Eurell, T E, Eurell, J A, Schaeffer, D J, Mattie, D R, Alden, C L

“…A histochemical stain for acid phosphatase served as a marker for lysosomal alterations in renal tubular cells associated with male rat hyaline droplet…”
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Alterations in alveolar clearance after 4-ipomeanol-induced necrosis of Clara and ciliated cells in the terminal bronchiole of the rat by Newton, P E, Latendresse, 2nd, J R, Mattie, D R, Pfledderer, C

“…The administration of 4-ipomeanol, [0, 10 (LD), and 25 (HD) mg/kg, ip], to rats resulted in dose-dependent degeneration and necrosis of the nonciliated (Clara)…”
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