Search Results - "Mattia Boeri"

Biomarkers in Lung Cancer Screening: Achievements, Promises, and Challenges by Seijo, Luis M, Peled, Nir, Ajona, Daniel, Boeri, Mattia, Field, John K, Sozzi, Gabriella, Pio, Ruben, Zulueta, Javier J, Spira, Avrum, Massion, Pierre P, Mazzone, Peter J, Montuenga, Luis M

“…The present review is an update of the research and development efforts regarding the use of molecular biomarkers in the lung cancer screening setting. The two…”
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Antibody-Fc/FcR Interaction on Macrophages as a Mechanism for Hyperprogressive Disease in Non-small Cell Lung Cancer Subsequent to PD-1/PD-L1 Blockade by Lo Russo, Giuseppe, Moro, Massimo, Sommariva, Michele, Cancila, Valeria, Boeri, Mattia, Centonze, Giovanni, Ferro, Simona, Ganzinelli, Monica, Gasparini, Patrizia, Huber, Veronica, Milione, Massimo, Porcu, Luca, Proto, Claudia, Pruneri, Giancarlo, Signorelli, Diego, Sangaletti, Sabina, Sfondrini, Lucia, Storti, Chiara, Tassi, Elena, Bardelli, Alberto, Marsoni, Silvia, Torri, Valter, Tripodo, Claudio, Colombo, Mario Paolo, Anichini, Andrea, Rivoltini, Licia, Balsari, Andrea, Sozzi, Gabriella, Garassino, Marina Chiara

“…Hyperprogression (HP), a paradoxical boost in tumor growth, was described in a subset of patients treated with immune checkpoint inhibitors (ICI). Neither…”
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Clinical Utility of a Plasma-Based miRNA Signature Classifier Within Computed Tomography Lung Cancer Screening: A Correlative MILD Trial Study by SOZZI, Gabriella, BOERI, Mattia, MARCHIANO, Alfonso, NEGRI, Eva, LA VECCHIA, Carlo, PASTORINO, Ugo, ROSSI, Marta, VERRI, Carla, SUATONI, Paola, BRAVI, Francesca, ROZ, Luca, CONTE, Davide, GRASSI, Michela, SVERZELLATI, Nicola

“…Recent screening trial results indicate that low-dose computed tomography (LDCT) reduces lung cancer mortality in high-risk patients. However, high…”
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MicroRNA signatures in tissues and plasma predict development and prognosis of computed tomography detected lung cancer by Boeri, Mattia, Verri, Carla, Conte, Davide, Roz, Luca, Modena, Piergiorgio, Facchinetti, Federica, Calabrò, Elisa, Croce, Carlo M, Pastorino, Ugo, Sozzi, Gabriella

“…The efficacy of computed tomography (CT) screening for early lung cancer detection in heavy smokers is currently being tested by a number of randomized trials…”
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Establishment of patient derived xenografts as functional testing of lung cancer aggressiveness by Moro, Massimo, Bertolini, Giulia, Caserini, Roberto, Borzi, Cristina, Boeri, Mattia, Fabbri, Alessandra, Leone, Giorgia, Gasparini, Patrizia, Galeone, Carlotta, Pelosi, Giuseppe, Roz, Luca, Sozzi, Gabriella, Pastorino, Ugo

“…Despite many years of research efforts, lung cancer still remains the leading cause of cancer deaths worldwide. Objective of this study was to set up a…”
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Baseline and postoperative C-reactive protein levels predict mortality in operable lung cancer by Pastorino, Ugo, Morelli, Daniele, Leuzzi, Giovanni, Gisabella, Mara, Suatoni, Paola, Taverna, Francesca, Bertocchi, Elena, Boeri, Mattia, Sozzi, Gabriella, Cantarutti, Anna, Corrao, Giovanni

“…Abstract Background Higher blood levels of C-reactive protein (CRP) have been associated with shorter survival in patients with cardiovascular, chronic…”
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Assessment of circulating microRNAs in plasma of lung cancer patients by Fortunato, Orazio, Boeri, Mattia, Verri, Carla, Conte, Davide, Mensah, Mavis, Suatoni, Paola, Pastorino, Ugo, Sozzi, Gabriella

“…Lung cancer is the most common cause of cancer deaths worldwide and numerous ongoing research efforts are directed to identify new strategies for its early…”
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Timeline of SARS-CoV-2 Spread in Italy: Results from an Independent Serological Retesting by Montomoli, Emanuele, Apolone, Giovanni, Manenti, Alessandro, Boeri, Mattia, Suatoni, Paola, Sabia, Federica, Marchianò, Alfonso, Bollati, Valentina, Pastorino, Ugo, Sozzi, Gabriella

“…The massive emergence of COVID-19 cases in the first phase of pandemic within an extremely short period of time suggest that an undetected earlier circulation…”
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MiR-486-5p Targets CD133+ Lung Cancer Stem Cells through the p85/AKT Pathway by Moro, Massimo, Fortunato, Orazio, Bertolini, Giulia, Mensah, Mavis, Borzi, Cristina, Centonze, Giovanni, Andriani, Francesca, Di Paolo, Daniela, Perri, Patrizia, Ponzoni, Mirco, Pastorino, Ugo, Sozzi, Gabriella, Boeri, Mattia

“…Despite improvements in therapies and screening strategies, lung cancer prognosis still remains dismal, especially for metastatic tumors. Cancer stem cells…”
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MicroRNA Based Liquid Biopsy: The Experience of the Plasma miRNA Signature Classifier (MSC) for Lung Cancer Screening by Mensah, Mavis, Borzi, Cristina, Verri, Carla, Suatoni, Paola, Conte, Davide, Pastorino, Ugo, Orazio, Fortunato, Sozzi, Gabriella, Boeri, Mattia

“…The development of a minimally invasive test, such as liquid biopsy, for early lung cancer detection in its preclinical phase is crucial to improve the outcome…”
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Baseline and Postoperative C-reactive Protein Levels Predict Long-Term Survival After Lung Metastasectomy by Pastorino, Ugo, Morelli, Daniele, Leuzzi, Giovanni, Rolli, Luigi, Suatoni, Paola, Taverna, Francesca, Bertocchi, Elena, Boeri, Mattia, Sozzi, Gabriella, Cantarutti, Anna, Corrao, Giovanni, Gronchi, Alessandro

“…Background Blood level of C-reactive protein (CRP) at diagnosis is a well-know prognostic bio-marker in different primary tumors, but its role has not been…”
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A Cross-Comparison of High-Throughput Platforms for Circulating MicroRNA Quantification, Agreement in Risk Classification, and Biomarker Discovery in Non-Small Cell Lung Cancer by Gargiuli, Chiara, De Cecco, Loris, Mariancini, Andrea, Iannò, Maria Federica, Micali, Arianna, Mancinelli, Elisa, Boeri, Mattia, Sozzi, Gabriella, Dugo, Matteo, Sensi, Marialuisa

“…BackgroundCirculating microRNAs (ct-miRs) are promising cancer biomarkers. This study focuses on platform comparison to assess performance variability,…”
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Prognostic determinants in epithelioid sarcoma by Gasparini, Patrizia, Facchinetti, Federica, Boeri, Mattia, Lorenzetto, Erica, Livio, Anna, Gronchi, Alessandro, Ferrari, Andrea, Massimino, Maura, Spreafico, Filippo, Giangaspero, Felice, Forni, Marco, Maestro, Roberta, Alaggio, Rita, Pilotti, Silvana, Collini, Paola, Modena, Piergiorgio, Sozzi, Gabriella

“…Abstract Background Epithelioid sarcoma (ES) is a rare soft tissue neoplasm that usually arises in the distal extremities of young adults, presents a high rate…”
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Gene Signatures Stratify Computed Tomography Screening Detected Lung Cancer in High-Risk Populations by Hu, Jiangting, Boeri, Mattia, Sozzi, Gabriella, Liu, Dongxia, Marchianò, Alfonso, Roz, Luca, Pelosi, Giuseppe, Gatter, Kevin, Pastorino, Ugo, Pezzella, Francesco

“…Although screening programmes of smokers have detected resectable early lung cancers more frequently than expected, their efficacy in reducing mortality…”
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Potential biomarkers for lung cancer screening by Sozzi, Gabriella, Boeri, Mattia

“…Notwithstanding the encouraging results of the National Lung Screening Trial (NLST) the scientific community still debates on the cost-benefit profile of low…”
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Exo-miRNAs as a New Tool for Liquid Biopsy in Lung Cancer by Fortunato, Orazio, Gasparini, Patrizia, Boeri, Mattia, Sozzi, Gabriella

“…Lung cancer is the predominant cause of cancer-related deaths. The high mortality rates are mainly due to the lack of diagnosis before the cancer is at a late…”
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Role of microRNAs in lung cancer: microRNA signatures in cancer prognosis by Boeri, Mattia, Pastorino, Ugo, Sozzi, Gabriella

“…Lung cancer-related mortality is the most common cause of cancer death worldwide. Detecting lung cancer at an earlier stage and, ideally, predicting who will…”
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Unexpected detection of SARS-CoV-2 antibodies in the prepandemic period in Italy by Apolone, Giovanni, Montomoli, Emanuele, Manenti, Alessandro, Boeri, Mattia, Sabia, Federica, Hyseni, Inesa, Mazzini, Livia, Martinuzzi, Donata, Cantone, Laura, Milanese, Gianluca, Sestini, Stefano, Suatoni, Paola, Marchianò, Alfonso, Bollati, Valentina, Sozzi, Gabriella, Pastorino, Ugo

“…There are no robust data on the real onset of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and spread in the prepandemic period…”
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Circulating miRNAs and PD-L1 Tumor Expression Are Associated with Survival in Advanced NSCLC Patients Treated with Immunotherapy: a Prospective Study by Boeri, Mattia, Milione, Massimo, Proto, Claudia, Signorelli, Diego, Lo Russo, Giuseppe, Galeone, Carlotta, Verri, Carla, Mensah, Mavis, Centonze, Giovanni, Martinetti, Antonia, Sottotetti, Elisa, Pastorino, Ugo, Garassino, Marina Chiara, Sozzi, Gabriella

“…Immune-checkpoint inhibitors (ICI) have improved the survival of patients with non-small cell lung cancer (NSCLC). However, only a subset of patients benefit…”
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Cytisine Therapy Improved Smoking Cessation in the Randomized Screening and Multiple Intervention on Lung Epidemics Lung Cancer Screening Trial by Pastorino, Ugo, Ladisa, Vito, Trussardo, Sara, Sabia, Federica, Rolli, Luigi, Valsecchi, Camilla, Ledda, Roberta E, Milanese, Gianluca, Suatoni, Paola, Boeri, Mattia, Sozzi, Gabriella, Marchianò, Alfonso, Munarini, Elena, Boffi, Roberto, Gallus, Silvano, Apolone, Giovanni

“…Cytisine, a partial agonist-binding nicotine acetylcholine receptor, is a promising cessation intervention. We conducted a single-center, randomized,…”
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