Search Results - "Matthies, H. J. G"

Closer Look at Amphetamine-Induced Reverse Transport and Trafficking of the Dopamine and Norepinephrine Transporters by Robertson, S. D, Matthies, H. J. G, Galli, A

“…Amphetamine (AMPH) and its derivatives are regularly used in the treatment of a wide array of disorders such as attention-deficit hyperactivity disorder…”
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SLC6A3 coding variant Ala559Val found in two autism probands alters dopamine transporter function and trafficking by Bowton, E, Saunders, C, Reddy, I A, Campbell, N G, Hamilton, P J, Henry, L K, Coon, H, Sakrikar, D, Veenstra-VanderWeele, J M, Blakely, R D, Sutcliffe, J, Matthies, H J G, Erreger, K, Galli, A

“…Emerging evidence associates dysfunction in the dopamine (DA) transporter (DAT) with the pathophysiology of autism spectrum disorder (ASD). The human DAT…”
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De novo mutation in the dopamine transporter gene associates dopamine dysfunction with autism spectrum disorder by Hamilton, P J, Campbell, N G, Sharma, S, Erreger, K, Herborg Hansen, F, Saunders, C, Belovich, A N, Sahai, M A, Cook, E H, Gether, U, Mchaourab, H S, Matthies, H J G, Sutcliffe, J S, Galli, A

“…De novo genetic variation is an important class of risk factors for autism spectrum disorder (ASD). Recently, whole-exome sequencing of ASD families has…”
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mTORC2/rictor signaling disrupts dopamine-dependent behaviors via defects in striatal dopamine neurotransmission by Dadalko, Olga I, Siuta, Michael, Poe, Amanda, Erreger, Kevin, Matthies, Heinrich J G, Niswender, Kevin, Galli, Aurelio

“…Disrupted neuronal protein kinase B (Akt) signaling has been associated with dopamine (DA)-related neuropsychiatric disorders, including schizophrenia, a…”
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Rab11 supports amphetamine-stimulated norepinephrine transporter trafficking by Matthies, Heinrich J G, Moore, Jessica L, Saunders, Christine, Matthies, Dawn Signor, Lapierre, Lynne A, Goldenring, James R, Blakely, Randy D, Galli, Aurelio

“…The norepinephrine transporter (NET) is a presynaptic plasma membrane protein that mediates reuptake of synaptically released norepinephrine. NET is also a…”
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Drosophila melanogaster: a novel animal model for the behavioral characterization of autism-associated mutations in the dopamine transporter gene by Hamilton, P J, Campbell, N G, Sharma, S, Erreger, K, Hansen, F H, Saunders, C, Belovich, A N, Sahai, M A, Cook, E H, Gether, U, Mchaourab, H S, Matthies, H J G, Sutcliffe, J S, Galli, A

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Calmodulin binding to and cAMP-dependent phosphorylation of kinesin light chains modulate kinesin ATPase activity by Matthies, H.J., Miller, R.J., Palfrey, H.C.

“…Kinesin is an ubiquitous heterotetrameric microtubule-based motor which translocates membrane-bound organelles. Since organelle motility and motor protein…”
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Down regulation of protein kinase C in neuronal cells: effects on neurotransmitter release by Matthies, HJ, Palfrey, HC, Hirning, LD, Miller, RJ

“…We investigated the effects of phorbol esters on protein kinase C (PKC) activity and on neurotransmitter release from cultured neuronal cells. Both…”
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Transfer of cholesterol from its site of synthesis to the plasma membrane by Lange, Y, Matthies, H J

“…We have followed the transfer of newly synthesized cholesterol to the plasma membrane in cultured fibroblasts using cholesterol oxidase as a probe. Since the…”
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Calmodulin- and protein phosphorylation-independent release of catecholamines from PC-12 cells by Matthies, Heinrich J.G., Palfrey, H.Clive, Miller, Richard J.

“…Catecholamine secretion from PC-12 cells can be triggered by agents that increase intracellular Ca 2+ and is enhanced by phorbol esters and agents that elevate…”
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The effect of down regulation of protein kinase C on the inhibitory modulation of dorsal root ganglion neuron Ca2+ currents by neuropeptide Y by Ewald, DA, Matthies, HJ, Perney, TM, Walker, MW, Miller, RJ

“…Dorsal root ganglion (DRG) neurons cultured from neonatal rats contained high concentrations of protein kinase C (PKC). Normally, the majority of the enzyme…”
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