Search Results - "Matthias Schmidt"

Afferent and efferent connections of the nucleus posterior tuberis in the firemouth cichlid, Thorichthys meeki by Schmidt, Matthias

“…The nucleus posterior tuberis (NPT) in teleost fishes, also called posterior tuberal nucleus, is situated in the posterior tuberculum of the diencephalon. It…”
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Power generation based on the Ca(OH)2/ CaO thermochemical storage system – Experimental investigation of discharge operation modes in lab scale and corresponding conceptual process design by Schmidt, Matthias, Linder, Marc

“…•Experimental investigation of thermal discharging in a lab scale reactor.•Operation of storage system at 4–470kPa and temperatures of 280–600°C.•Demonstration…”
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Cryo-EM structure and polymorphism of Aβ amyloid fibrils purified from Alzheimer’s brain tissue by Kollmer, Marius, Close, William, Funk, Leonie, Rasmussen, Jay, Bsoul, Aref, Schierhorn, Angelika, Schmidt, Matthias, Sigurdson, Christina J., Jucker, Mathias, Fändrich, Marcus

“…The formation of Aβ amyloid fibrils is a neuropathological hallmark of Alzheimer’s disease and cerebral amyloid angiopathy. However, the structure of Aβ…”
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Cryo-EM structure of a transthyretin-derived amyloid fibril from a patient with hereditary ATTR amyloidosis by Schmidt, Matthias, Wiese, Sebastian, Adak, Volkan, Engler, Jonas, Agarwal, Shubhangi, Fritz, Günter, Westermark, Per, Zacharias, Martin, Fändrich, Marcus

“…ATTR amyloidosis is one of the worldwide most abundant forms of systemic amyloidosis. The disease is caused by the misfolding of transthyretin protein and the…”
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Regulation of G2/M Transition by Inhibition of WEE1 and PKMYT1 Kinases by Schmidt, Matthias, Rohe, Alexander, Platzer, Charlott, Najjar, Abdulkarim, Erdmann, Frank, Sippl, Wolfgang

“…In the cell cycle, there are two checkpoint arrests that allow cells to repair damaged DNA in order to maintain genomic integrity. Many cancer cells have…”
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Noether’s theorem in statistical mechanics by Hermann, Sophie, Schmidt, Matthias

“…Noether’s calculus of invariant variations yields exact identities from functional symmetries. The standard application to an action integral allows to…”
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Comparison of Objective Image Quality Metrics to Expert Radiologists' Scoring of Diagnostic Quality of MR Images by Mason, Allister, Rioux, James, Clarke, Sharon E., Costa, Andreu, Schmidt, Matthias, Keough, Valerie, Huynh, Thien, Beyea, Steven

“…Image quality metrics (IQMs) such as root mean square error (RMSE) and structural similarity index (SSIM) are commonly used in the evaluation and optimization…”
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Peptide dimer structure in an Aβ(1–42) fibril visualized with cryo-EM by Schmidt, Matthias, Rohou, Alexis, Lasker, Keren, Yadav, Jay K., Schiene-Fischer, Cordelia, Fändrich, Marcus, Grigorieff, Nikolaus

“…Alzheimer’s disease (AD) is a fatal neurodegenerative disorder in humans and the main cause of dementia in aging societies. The disease is characterized by the…”
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Variance of fluctuations from Noether invariance by Hermann, Sophie, Schmidt, Matthias

“…The strength of fluctuations, as measured by their variance, is paramount in the quantitative description of a large class of physical systems, ranging from…”
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Cryo-EM structure of a light chain-derived amyloid fibril from a patient with systemic AL amyloidosis by Radamaker, Lynn, Lin, Yin-Hsi, Annamalai, Karthikeyan, Huhn, Stefanie, Hegenbart, Ute, Schönland, Stefan O., Fritz, Günter, Schmidt, Matthias, Fändrich, Marcus

“…Amyloid fibrils derived from antibody light chains are key pathogenic agents in systemic AL amyloidosis. They can be deposited in multiple organs but cardiac…”
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Experimental results of a 10 kW high temperature thermochemical storage reactor based on calcium hydroxide by Schmidt, Matthias, Szczukowski, Christoph, Roßkopf, Christian, Linder, Marc, Wörner, Antje

“…One promising possibility to store thermal energy is by means of reversible gas solid reactions. In this context, the endothermal dehydration of calcium…”
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Physical basis of amyloid fibril polymorphism by Close, William, Neumann, Matthias, Schmidt, Andreas, Hora, Manuel, Annamalai, Karthikeyan, Schmidt, Matthias, Reif, Bernd, Schmidt, Volker, Grigorieff, Nikolaus, Fändrich, Marcus

“…Polymorphism is a key feature of amyloid fibril structures but it remains challenging to explain these variations for a particular sample. Here, we report…”
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Cryo-EM structure of a catalytic amyloid fibril by Heerde, Thomas, Bansal, Akanksha, Schmidt, Matthias, Fändrich, Marcus

“…Catalytic amyloid fibrils are novel types of bioinspired, functional materials that combine the chemical and mechanical robustness of amyloids with the ability…”
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Cryo-EM reveals structural breaks in a patient-derived amyloid fibril from systemic AL amyloidosis by Radamaker, Lynn, Baur, Julian, Huhn, Stefanie, Haupt, Christian, Hegenbart, Ute, Schönland, Stefan, Bansal, Akanksha, Schmidt, Matthias, Fändrich, Marcus

“…Systemic AL amyloidosis is a debilitating and potentially fatal disease that arises from the misfolding and fibrillation of immunoglobulin light chains (LCs)…”
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Experimental Study on Heat Recovery in a CaO/Ca(OH)2-Based Mechanical Fluidized Bed Thermochemical Energy Storage Reactor by Kühl, Viktor, Linder, Marc, Schmidt, Matthias

“…Long-term storage of seasonally available solar energy and its provision to balance heating energy demand can contribute significantly to the sustainable use…”
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Self-bound dipolar droplets and supersolids in molecular Bose-Einstein condensates by Schmidt, Matthias, Lassablière, Lucas, Quéméner, Goulven, Langen, Tim

“…We numerically study the many-body physics of molecular Bose-Einstein condensates with strong dipole-dipole interactions. We observe the formation of…”
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Cryo-EM structure of an ATTRwt amyloid fibril from systemic non-hereditary transthyretin amyloidosis by Steinebrei, Maximilian, Gottwald, Juliane, Baur, Julian, Röcken, Christoph, Hegenbart, Ute, Schönland, Stefan, Schmidt, Matthias

“…Wild type transthyretin-derived amyloid (ATTRwt) is the major component of non-hereditary transthyretin amyloidosis. Its accumulation in the heart of elderly…”
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High resolution microscopy to evaluate the efficiency of surface sterilization of Zea Mays seeds by Davoudpour, Yalda, Schmidt, Matthias, Calabrese, Federica, Richnow, Hans Hermann, Musat, Niculina

“…Surface sterilization of seeds is a key step in providing microorganisms-free seeds for numerous applications like understanding the role of seed-borne…”
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AA amyloid fibrils from diseased tissue are structurally different from in vitro formed SAA fibrils by Bansal, Akanksha, Schmidt, Matthias, Rennegarbe, Matthies, Haupt, Christian, Liberta, Falk, Stecher, Sabrina, Puscalau-Girtu, Ioana, Biedermann, Alexander, Fändrich, Marcus

“…Systemic AA amyloidosis is a world-wide occurring protein misfolding disease of humans and animals. It arises from the formation of amyloid fibrils from serum…”
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Cryo-EM fibril structures from systemic AA amyloidosis reveal the species complementarity of pathological amyloids by Liberta, Falk, Loerch, Sarah, Rennegarbe, Matthies, Schierhorn, Angelika, Westermark, Per, Westermark, Gunilla T., Hazenberg, Bouke P. C., Grigorieff, Nikolaus, Fändrich, Marcus, Schmidt, Matthias

“…Systemic AA amyloidosis is a worldwide occurring protein misfolding disease of humans and animals. It arises from the formation of amyloid fibrils from the…”
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