Search Results - "Matthews, Vance B"

Role of the sympathetic nervous system in regulation of the sodium glucose cotransporter 2 by Matthews, Vance B, Elliot, Rosemary H, Rudnicka, Caroline, Hricova, Jana, Herat, Lakshini, Schlaich, Markus P

“…BACKGROUND:The sympathetic nervous system (SNS) regulates glucose metabolism in various organs including the kidneys. The sodium glucose cotransporter 2…”
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Blocking IL-6 trans-Signaling Prevents High-Fat Diet-Induced Adipose Tissue Macrophage Recruitment but Does Not Improve Insulin Resistance by Kraakman, Michael J., Kammoun, Helene L., Allen, Tamara L., Deswaerte, Virginie, Henstridge, Darren C., Estevez, Emma, Matthews, Vance B., Neill, Bronwyn, White, David A., Murphy, Andrew J., Peijs, Lone, Yang, Christine, Risis, Steve, Bruce, Clinton R., Du, Xiao-Jun, Bobik, Alex, Lee-Young, Robert S., Kingwell, Bronwyn A., Vasanthakumar, Ajithkumar, Shi, Wei, Kallies, Axel, Lancaster, Graeme I., Rose-John, Stefan, Febbraio, Mark A.

“…Interleukin-6 (IL-6) plays a paradoxical role in inflammation and metabolism. The pro-inflammatory effects of IL-6 are mediated via IL-6 “trans-signaling,” a…”
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Multi-organ denervation: a novel approach to combat cardiometabolic disease by Kiuchi, Márcio Galindo, Carnagarin, Revathy, Matthews, Vance B, Schlaich, Markus P

“…Cardiometabolic disorders are associated with a substantial loss in quality of life and pose a large burden on healthcare systems worldwide. Overactivation of…”
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Interaction between sodium-glucose co-transporter 2 and the sympathetic nervous system by Azzam, Omar, Matthews, Vance B., Schlaich, Markus P.

“…Sodium-glucose co-transporter 2 (SGLT2) inhibitors have taken centre stage in research and therapeutic efforts to modulate hard clinical outcomes in patients…”
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Isoquercetin and inulin synergistically modulate the gut microbiome to prevent development of the metabolic syndrome in mice fed a high fat diet by Tan, Si, Caparros-Martin, Jose A., Matthews, Vance B., Koch, Henrietta, O’Gara, Fergal, Croft, Kevin D., Ward, Natalie C.

“…Dietary fibre positively influences gut microbiome composition, enhancing the metabolism of dietary flavonoids to produce bioactive metabolites. These…”
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Evaluation of Circulating Platelet Extracellular Vesicles and Hypertension Mediated Organ Damage by Lugo-Gavidia, Leslie Marisol, Burger, Dylan, Nolde, Janis M, Matthews, Vance B, Schlaich, Markus P

“…Elevated circulating platelet-derived extracellular vesicles (pEVs) have been associated with arterial hypertension. The role of hypertension-mediated organ…”
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Sympathetic Nervous System Activation and Its Modulation: Role in Atrial Fibrillation by Carnagarin, Revathy, Kiuchi, Marcio G, Ho, Jan K, Matthews, Vance B, Schlaich, Markus P

“…The autonomic nervous system (ANS) has a significant influence on the structural integrity and electrical conductivity of the atria. Aberrant activation of the…”
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Metabolic Dysfunction-Associated Fatty Liver Disease (MAFLD)-A Condition Associated with Heightened Sympathetic Activation by Carnagarin, Revathy, Tan, Kearney, Adams, Leon, Matthews, Vance B, Kiuchi, Marcio G, Marisol Lugo Gavidia, Leslie, Lambert, Gavin W, Lambert, Elisabeth A, Herat, Lakshini Y, Schlaich, Markus P

“…Metabolic dysfunction-associated fatty liver disease (MAFLD) is the most common liver disease affecting a quarter of the global population and is often…”
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Association of Circulating Platelet Extracellular Vesicles and Pulse Wave Velocity with Cardiovascular Risk Estimation by Lugo-Gavidia, Leslie Marisol, Nolde, Janis M, Carnagarin, Revathy, Burger, Dylan, Chan, Justine, Robinson, Sandi, Bosio, Erika, Matthews, Vance B, Schlaich, Markus P

“…Elevated circulating platelet-derived extracellular vesicles (EVs) have been reported in conditions associated with thrombotic risk. The present study aimed to…”
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Retinal capillary rarefaction is associated with arterial and kidney damage in hypertension by Frost, Shaun, Nolde, Janis Marc, Chan, Justine, Joyson, Anu, Gregory, Cynthia, Carnagarin, Revathy, Herat, Lakshini Y., Matthews, Vance B., Robinson, Liam, Vignarajan, Janardhan, Prentice, David, Kanagasingam, Yogesan, Schlaich, Markus P.

“…Microvascular disease and rarefaction are key pathological hallmarks of hypertension. The retina uniquely allows direct, non-invasive investigation of the…”
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Role of exercise-induced brain-derived neurotrophic factor production in the regulation of energy homeostasis in mammals by Pedersen, Bente K., Pedersen, Maria, Krabbe, Karen S., Bruunsgaard, Helle, Matthews, Vance B., Febbraio, Mark A.

“…Brain-derived neurotrophic factor (BDNF) has been shown to regulate neuronal development and plasticity and plays a role in learning and memory. Moreover, it…”
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Maternal high fat diet compromises survival and modulates lung development of offspring, and impairs lung function of dams (female mice) by Smoothy, Jordan, Larcombe, Alexander N, Chivers, Emily K, Matthews, Vance B, Gorman, Shelley

“…Epidemiological studies have identified strong relationships between maternal obesity and offspring respiratory dysfunction; however, the causal direction is…”
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Correction to: Maternal high fat diet compromises survival and modulates lung development of offspring, and impairs lung function of dams (female mice) by Smoothy, Jordan, Larcombe, Alexander N, Chivers, Emily K, Matthews, Vance B, Gorman, Shelley

“…An amendment to this paper has been published and can be accessed via the original article…”
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Circulating platelet‐derived extracellular vesicles correlate with night‐time blood pressure and vascular organ damage and may represent an integrative biomarker of vascular health by Lugo‐Gavidia, Leslie Marisol, Carnagarin, Revathy, Burger, Dylan, Nolde, Janis M., Chan, Justine, Robinson, Sandi, Bosio, Erika, Matthews, Vance B., Schlaich, Markus P.

“…Elevated office blood pressure (BP) has previously been associated with increased levels of circulating extracellular vesicles (EVs). The present study aimed…”
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New Approaches in the Management of Sudden Cardiac Death in Patients with Heart Failure-Targeting the Sympathetic Nervous System by Kiuchi, Márcio Galindo, Nolde, Janis Marc, Villacorta, Humberto, Carnagarin, Revathy, Chan, Justine Joy Su-Yin, Lugo-Gavidia, Leslie Marisol, Ho, Jan K, Matthews, Vance B, Dwivedi, Girish, Schlaich, Markus P

“…Cardiovascular diseases (CVDs) have been considered the most predominant cause of death and one of the most critical public health issues worldwide. In the…”
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Sympathetic Activation in Hypertensive Chronic Kidney Disease - A Stimulus for Cardiac Arrhythmias and Sudden Cardiac Death? by Kiuchi, Márcio Galindo, Ho, Jan K, Nolde, Janis Marc, Gavidia, Leslie Marisol Lugo, Carnagarin, Revathy, Matthews, Vance B, Schlaich, Markus P

“…Studies have revealed a robust and independent correlation between chronic kidney disease (CKD) and cardiovascular (CV) events, including death, heart failure,…”
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TNFSF14-Derived Molecules as a Novel Treatment for Obesity and Type 2 Diabetes by Agostino, Mark, Rooney, Jennifer, Herat, Lakshini, Matthews, Jennifer, Simonds, Allyson, Northfield, Susan E., Hopper, Denham, Schlaich, Markus P., Matthews, Vance B.

“…Obesity is one of the most prevalent metabolic diseases in the Western world and correlates directly with glucose intolerance and insulin resistance, often…”
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Contraction-induced Interleukin-6 Gene Transcription in Skeletal Muscle Is Regulated by c-Jun Terminal Kinase/Activator Protein-1 by Whitham, Martin, Chan, M.H. Stanley, Pal, Martin, Matthews, Vance B., Prelovsek, Oja, Lunke, Sebastian, El-Osta, Assam, Broenneke, Hella, Alber, Jens, Brüning, Jens C., Wunderlich, F. Thomas, Lancaster, Graeme I., Febbraio, Mark A.

“…Exercise increases the expression of the prototypical myokine IL-6, but the precise mechanism by which this occurs has yet to be identified. To mimic exercise…”
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Interleukin-18 Activates Skeletal Muscle AMPK and Reduces Weight Gain and Insulin Resistance in Mice by LINDEGAARD, Birgitte, MATTHEWS, Vance B, RUDNICKA, Caroline, ABILDGAARD, Julie, PILEGAARD, Henriette, HIDALGO, Juan, DITLEVSEN, Susanne, ALSTED, Thomas J, MADSEN, Andreas N, PEDERSEN, Bente K, FEBBRAIO, Mark A, BRANDT, Claus, HOJMAN, Pernille, ALLEN, Tamara L, ESTEVEZ, Emma, WATT, Matthew J, BRUCE, Clinton R, MORTENSEN, Ole H, SYBERG, Susanne

“…Circulating interleukin (IL)-18 is elevated in obesity, but paradoxically causes hypophagia. We hypothesized that IL-18 may attenuate high-fat diet…”
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Sympathetic Activation Promotes Sodium Glucose Co-Transporter-1 Protein Expression in Rodent Skeletal Muscle by Matthews, Jennifer R, Herat, Lakshini Y, Schlaich, Markus P, Matthews, Vance B

“…The hyperactivation of the sympathetic nervous system (SNS) is linked to obesity, hypertension, and type 2 diabetes, which are characterized by elevated…”
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