Search Results - "Matthews, E J"

The epidemiology of published norovirus outbreaks: a review of risk factors associated with attack rate and genogroup by MATTHEWS, J. E., DICKEY, B. W., MILLER, R. D., FELZER, J. R., DAWSON, B. P., LEE, A. S., ROCKS, J. J., KIEL, J., MONTES, J. S., MOE, C. L., EISENBERG, J. N. S., LEON, J. S.

“…The purpose of this study was to examine global epidemiological trends in human norovirus (NoV) outbreaks by transmission route and setting, and describe…”
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Norovirus outbreaks: a systematic review of commonly implicated transmission routes and vehicles by BITLER, E. J., MATTHEWS, J. E., DICKEY, B. W., EISENBERG, J. N. S., LEON, J. S.

“…Causal mechanisms of norovirus outbreaks are often not revealed. Understanding the transmission route (e.g. foodborne, waterborne, or environmental) and…”
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Safety, tolerability, pharmacodynamics and pharmacokinetics of albiglutide, a long-acting glucagon-like peptide-1 mimetic, in healthy subjects by Bush, M.A, Matthews, J.E, De Boever, E.H, Dobbins, R.L, Hodge, R.J, Walker, S.E, Holland, M.C, Gutierrez, M, Stewart, M.W

“…Albiglutide is a glucagon-like peptide-1 (GLP-1) mimetic generated by genetic fusion of a dipeptidyl peptidase-IV-resistant GLP-1 dimer to human albumin…”
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Innovations in osteosynthesis and fracture care by Matthews, Stuart J.E, Nikolaou, Vassilios S, Giannoudis, Peter V

“…Summary Over the years giant steps have been made in the evolution of fracture fixation and the overall clinical care of patients. Better understanding of the…”
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An analysis of genetic toxicity, reproductive and developmental toxicity, and carcinogenicity data: I. Identification of carcinogens using surrogate endpoints by Matthews, Edwin J., Kruhlak, Naomi L., Cimino, Michael C., Benz, R. Daniel, Contrera, Joseph F.

“…A retrospective analysis of standard genetic toxicity (genetox) tests, reproductive and developmental toxicity (reprotox) studies, and rodent carcinogenicity…”
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Food intake inhibition and reduction in body weight gain in lean and obese rodents treated with GW438014A, a potent and selective NPY-Y5 receptor antagonist by Daniels, A.J., Grizzle, M.K., Wiard, R.P., Matthews, J.E., Heyer, D.

“…Numerous reports have implicated theY5 receptor as the ‘feeding’ receptor mediating the orexigenic action of neuropeptide Y (NPY). This notion is supported by…”
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A new highly specific method for predicting the carcinogenic potential of pharmaceuticals in rodents using enhanced MCASE QSAR-ES software by MATTHEWS, E. J, CONTRERA, J. F

“…This report describes in detail a new quantitative structure-activity relational expert system (QSAR-ES) method for predicting the carcinogenic potential of…”
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Fractures of the distal humerus in the elderly: is internal fixation the treatment of choice? by Srinivasan, K, Agarwal, M, Matthews, S J E, Giannoudis, P V

“…The incidence of osteoporotic fractures of the distal humerus is increasing, and the treatment of these injuries merits closer review. We assessed the results…”
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High-Affinity Neuropeptide Y Receptor Antagonists by Daniels, Alejandro J., Matthews, Jessica E., Slepetis, Ruta J., Jansen, Marilyn, Viveros, O. Humberto, Tadepalli, Anjaneyulu, Harrington, Wallace, Heyer, Dennis, Landavazo, Antonio, Leban, Johann J., Spaltenstein, Andrew

“…Neuropeptide Y (NPY) is one of the most abundant peptide transmitters in the mammalian brain. In the periphery it is costored and coreleased with…”
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An in silico expert system for the identification of eye irritants by Verma, R.P., Matthews, E.J.

“…This report describes development of an in silico, expert rule-based method for the classification of chemicals into irritants or non-irritants to eye, as…”
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The Biogeochemistry of Polychlorinated Biphenyls (PCBs) in the Clyde: Distribution and Source Evaluation by Edgar, P.J., Davies, I.M., Hursthouse, A.S., Matthews, J.E.

“…The River Clyde, on the West coast of Scotland, has a long history as a recipient of waste from heavy industries, including shipbuilding, textile…”
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IMPLEMENTATION OF A SCHOOL-BASED HIV PREVENTION CURRICULUM FOLLOWING NATIONAL DISSEMINATION IN NYANZA PROVINCE, KENYA by Matthews, E J, Puffer, E S, Meade, C S, Broverman, S A

“…Primary School Action for Better Health (PSABH) became the national HIV prevention curriculum of Kenya in 2005. To examined implementation of PSABH and student…”
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Early internal fixation and soft tissue cover of severe open tibial pilon fractures by CONROY, J, AGARWAL, M, GIANNOUDIS, P. V, MATTHEWS, S. J. E

“…We studied 32 consecutive patients with open distal tibial pilon fractures. All patients had radical debridement with immediate skeletal stabilisation and…”
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Food intake inhibition and reduction in body weight gain in rats treated with GI264879A, a non-selective NPY-Y1 receptor antagonist by Danielsa, A.J, Chance, W.T, Grizzle, M.K, Heyer, D, Matthews, J.E

“…Neuropeptide Y has been proposed to play a major role in the hypothalamic regulation of feeding behavior through the activation of specific, central NPY…”
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ICare-ACS (Improving Care Processes for Patients With Suspected Acute Coronary Syndrome): A Study of Cross-System Implementation of a National Clinical Pathway by Than, Martin P, Pickering, John W, Dryden, Jeremy M, Lord, Sally J, Aitken, S Andrew, Aldous, Sally J, Allan, Kate E, Ardagh, Michael W, Bonning, John W.N, Callender, Rosie, Chapman, Laura R.E, Christiansen, Jonathan P, Cromhout, Andre P.J, Cullen, Louise, Deely, Joanne M, Devlin, Gerard P, Ferrier, Katherine A, Florkowski, Christopher M, Frampton, Christopher M.A, George, Peter M, Hamilton, Gregory J, Jaffe, Allan S, Kerr, Andrew J, Larkin, G Luke, Makower, Richard M, Matthews, Timothy J.E, Parsonage, William A, Peacock, W Frank, Peckler, Bradley F, van Pelt, Niels C, Poynton, Louise, Richards, A Mark, Scott, Anthony G, Simmonds, Mark B, Smyth, David, Thomas, Oliver P, To, Andrew C.Y, Du Toit, Stephen A, Troughton, Richard W, Yates, Kim M

“…BACKGROUND:Efforts to safely reduce length of stay for emergency department patients with symptoms suggestive of acute coronary syndrome (ACS) have had mixed…”
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Use of toxicological information in drug design by Matthews, E J, Benz, R D, Contrera, J F

“…This paper is an extension of the keynote address and another talk at the Symposium on the Use of Toxiciological Information in Drug Design. The symposium was…”
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Novel cypermethrin formulation for the control of sea lice on salmon (Salmo salar) by Hart, J. L., Thacker, J. R. M., Braidwood, J. C., Fraser, N. R., Matthews, J. E.

“…A novel formulation of cypermethrin was applied as a bath treatment to Atlantic salmon infested with sea lice on a commercial fish farm on the Isle of Skye,…”
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An analysis of genetic toxicity, reproductive and developmental toxicity, and carcinogenicity data: II. Identification of genotoxicants, reprotoxicants, and carcinogens using in silico methods by Matthews, Edwin J., Kruhlak, Naomi L., Cimino, Michael C., Benz, R. Daniel, Contrera, Joseph F.

“…This study examined a novel method to identify carcinogens that employed expanded data sets composed of in silico data pooled with actual experimental genetic…”
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Understanding Genetic Toxicity Through Data Mining: The Process of Building Knowledge by Integrating Multiple Genetic Toxicity Databases by Yang, C., Hasselgren, C. H., Boyer, S., Arvidson, K., Aveston, S., Dierkes, P., Benigni, R., Benz, R. D., Contrera, J., Kruhlak, N. L., Matthews, E. J., Han, X., Jaworska, J., Kemper, R. A., Rathman, J. F., Richard, A. M.

“…ABSTRACT Genetic toxicity data from various sources were integrated into a rigorously designed database using the ToxML schema. The public database sources…”
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Threshold of estimated toxicity for regulation of indirect food additives by Matthews, E.J., Machuga, E.J.

“…In response to the objectives of this ATSDR workshop, 2 new procedures are described for assessing the safe use of indirect food additives. First, this…”
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