Search Results - "Matthes, Eckart"

Detection of activity of telomerase in tumor cells using fiber optical biosensors by Schmidt, Peter M, Lehmann, Christine, Matthes, Eckart, Bier, Frank F

“…Human telomerase plays an important role in the cancerogenesis as it is up-regulated in 80–90% of malignant tumors. Thus, it is considered as a potential…”
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Strong antiviral activity of the new l-hydroxycytidine derivative, l-Hyd4FC, in HBV-infected human chimeric uPA/SCID mice by Volz, Tassilo, Lütgehetmann, Marc, Allweiss, Lena, Warlich, Michael, Bierwolf, Jeanette, Pollok, Joerg M, Petersen, Joerg, Matthes, Eckart, Dandri, Maura

“…Suppression of viral replication with nucleoside/nucleotide inhibitors has been shown to greatly improve the outcome of chronic HBV infection. β-l-nucleoside…”
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Up-regulation of telomerase activity in Herpesvirus saimiri immortalized human T-lymphocytes by Harnack, U, Lehmann, C, Matthes, E, Pecher, G

“…Human T-lymphocytes can be transformed to unlimited growth by Herpesvirus saimiri (HVS). We studied the telomerase activity of a recently established HVS…”
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Real-time determination of telomerase activity in cell extracts using an optical biosensor by Schmidt, Peter M, Matthes, Eckart, Scheller, Frieder W, Bienert, Michael, Lehmann, Christine, Ehrlich, Angelika, Bier, Frank F

“…A biosensoric approach has been developed to determine the activity of telomerase in tumor cell lysates. An optical sensor, the grating coupler, was used to…”
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Newly Synthesized l-Enantiomers of 3'-Fluoro-Modified β-2'-Deoxyribonucleoside 5'-Triphosphates Inhibit Hepatitis B DNA Polymerases But Not the Five Cellular DNA Polymerases α, β, γ, δ, and ε Nor HIV-1 Reverse Transcriptase by von Janta-Lipinski, Martin, Costisella, Burkhardt, Ochs, Hansueli, Hübscher, Ulrich, Hafkemeyer, Peter, Matthes, Eckart

“…Novel β-l-2',3'-dideoxy-3'-fluoro nucleosides were synthesized and further converted to their 5'-triphosphates. Their inhibitory activities against hepatitis B…”
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Chemo-enzymatic synthesis of a new type of enantiomerically pure carbocyclic nucleoside analogues with strong inhibitory effects on terminal deoxynucleotidyl transferase by Theil, Fritz, Ballschuh, Sibylle, Flatau, Sabine, von Janta-Lipinski, Martin, Matthes, Eckart

“…The synthesis of enantiomerically pure carbocyclic adenosine derivatives which have been prepared based on the kinetic resolution of a…”
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Inhibition of adenovirus DNA polymerase by modified nucleoside triphosphate analogs correlate with their antiviral effects on cellular level by MENTEL, Renate, KUREK, Stefan, WEGNER, Ursula, JANTA-LIPINSKI, Martin V, GÜRTLER, Lutz, MATTHES, Eckart

“…Adenovirus (Ad) infection results in significant morbidity and mortality in both immunocompetent and immunosuppressed hosts. There is currently no licensed…”
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Selective endocytosis of fluorothymidine and azidothymidine coupled to LDL into HIV infected mononuclear cells by Mankertz, Joachim, Matthes, Eckart, Rokos, Katharina, von Baeyer, Hans, Pauli, Georg, Riedel, Eberhard

“…Drug targeting via lipoproteins may be of benefit for use of cytotoxic drugs like fluorothymidine (FLT) or azidothymidine (AZT). Both drugs are potent…”
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Inhibition of expression of human immunodeficiency virus-1 in vitro by antibody-targeted liposomes containing antisense RNA to the env region by Renneisen, K, Leserman, L, Matthes, E, Schröder, H C, Müller, W E

“…Previous studies revealed that antisense oligodeoxynucleotides to specific regions of the human immunodeficiency virus-1 (HIV-1) are potent inhibitors of…”
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Inhibition of HIV-replication by 3'-fluoro-modified nucleosides with low cytotoxicity by Matthes, E, Lehmann, C, von Janta-Lipinski, M, Scholz, D

“…From a series of newly synthesized 3'-fluoro-modified nucleosides the C-5-chloro-substituted derivative of 2',3'-dideoxy-3'-fluorouridine (FddUrd) and the…”
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Inhibition of duck hepatitis B virus replication by 2',3'-dideoxy-3'-fluoroguanosine in vitro and in vivo by HAFKEMEYER, P, KEPPLER-HAFKEMEYER, A, MUNTASIR ABO AL HAYA, VON JANTA-LIPINSKI, M, MATTHES, E, LEHMANN, C, OFFENSPERGER, W.-B, OFFENSPERGER, S, GEROK, W, BLUM, H. E

“…Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit StumbleUpon…”
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Tamoxifen is a Na(+)-antagonistic inhibitor of Na+/K(+)-transporting ATPase from tumour and normal cells by Repke, K R, Matthes, E

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Avarol restores the altered prostaglandin and leukotriene metabolism in monocytes infected with human immunodeficiency virus type 1 by Schröder, H C, Bégin, M E, Klöcking, R, Matthes, E, Sarma, A S, Gasić, M, Müller, W E

“…Infection of monocytes with human immunodeficiency virus type 1 (HIV-1) (strain Ada-M) caused increased levels of leukotriene B4 (LTB4) and prostaglandin E2…”
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Inhibition of Human Immunodeficiency Virus‐1 Infection by Human Conglutinin‐like Protein: In vitro Studies by Ushijima, Hiroshi, Schröder, Heinz C., Poznanovic, Slobodan, Gasić, Miroslav J., Matthes, Eckart, Müller, Werner E. G.

“…The lectin‐like protein analogous to bovine conglutinin was purified from human serum. The carbohydrate‐binding ability of conglutinin‐like protein was…”
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Alteration of DNA topoisomerase II activity during infection of H9 cells by human immunodeficiency virus type 1 in vitro: a target for potential therapeutic agents by Matthes, E, Langen, P, Brachwitz, H, Schröder, H C, Maidhof, A, Weiler, B E, Renneisen, K, Müller, W E

“…Infection of H9 cells with human immunodeficiency virus type 1 (HIV-1) was found to decrease the phosphorylation of DNA topoisomerase II during the initial…”
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Potent inhibitory activity of chimeric oligonucleotides targeting two different sites of human telomerase by Matthes, Eckart, Lehmann, Christine, Stulich, Marianne, Wu, Yong, Dimitrova, Lora, Uhlmann, Eugen, Janta-Lipinski, Martin Von

“…Suppression of telomerase activity in tumor cells has been considered as a new anticancer strategy. Here, we present chimeric oligonucleotides (chimeric ODNs)…”
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Antisense oligodeoxynucleotide: inhibitor of splicing of mRNA of human immunodeficiency virus by Daum, T, Engels, J W, Mag, M, Muth, J, Lücking, S, Schröder, H C, Matthes, E, Müller, W E

“…Antisense oligodeoxynucleotide (ODN), which are directed against the splice acceptor site of exon II of the regulatory gene tat of the human immunodeficiency…”
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Human immunodeficiency virus: novel enzyme-linked immunoassays for quantitation of envelope glycoprotein 120 by Weiler, B E, Schäcke, H, Bachmann, M, Brigido, L, Gilbert, M, Mills, J, Matthes, E, Forrest, J M, Müller, W E

“…Two novel enzyme-linked immunoassays (ELISA) for the quantitation of human immunodeficiency virus type 1 (HIV-1) coded glycoprotein with an Mr 120 (gp120) are…”
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Lymphocyte reactivity in normal and malignant cell proliferation against a phylogenetically conserved antigen in fetal extracts by Pasternak, G, Schlott, B, Gryschek, G, Albrecht, S, Reinhöfer, J, Matthes, E, von Broen, B

“…Lymphocyte reactivity to 3-M KCl extracts from fetuses of different species of origin was shown by the macrophage electrophoretic mobility (MEMB) and/or the…”
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