Search Results - "Matthäi, Elvira"
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Combinations of Low-Frequency Genetic Variants Might Predispose to Familial Pancreatic Cancer
Published in Journal of personalized medicine (02-07-2021)“…Familial pancreatic cancer (FPC) is an established but rare inherited tumor syndrome that accounts for approximately 5% of pancreatic ductal adenocarcinoma…”
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German national case collection for familial pancreatic cancer (FaPaCa): ten years experience
Published in Familial cancer (01-06-2011)“…Familial pancreatic cancer (FPC) is a rare hereditary tumor syndrome. The 10-years experience of the national case collection for familial pancreatic cancer of…”
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MicroRNA-196a and -196b as Potential Biomarkers for the Early Detection of Familial Pancreatic Cancer
Published in Translational oncology (01-08-2014)“…Abstract Screening programs are recommended for individuals at risk (IAR) from families with familial pancreatic cancer (FPC). However, reliable imaging…”
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German National Case Collection for familial pancreatic Cancer (FaPaCa) - acceptance and psychological aspects of a pancreatic cancer screening program
Published in Hereditary cancer in clinical practice (29-11-2018)“…Pancreatic cancer screening is recommended to individuals at risk (IAR) of familial pancreatic cancer (FPC) families, but little is known about the acceptance…”
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The Combination of MiRNA-196b, LCN2, and TIMP1 is a Potential Set of Circulating Biomarkers for Screening Individuals at Risk for Familial Pancreatic Cancer
Published in Journal of clinical medicine (20-09-2018)“…Individuals at risk (IAR) of familial pancreatic cancer (FPC) are good candidates for screening. Unfortunately, neither reliable imaging modalities nor…”
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Benefit of Surveillance for Pancreatic Cancer in High-Risk Individuals: Outcome of Long-Term Prospective Follow-Up Studies From Three European Expert Centers
Published in Journal of clinical oncology (10-06-2016)“…Pancreatic ductal adenocarcinoma (PDAC) has a poor prognosis. Hereditary factors play a role in the development of PDAC in 3% to 5% of all patients…”
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LCN2 and TIMP1 as Potential Serum Markers for the Early Detection of Familial Pancreatic Cancer
Published in Translational oncology (01-04-2013)“…Abstract High-risk individuals of familial pancreatic cancer (FPC) families are considered to be good candidates for screening programs to detect early PC or…”
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Joint Linkage and Association Analysis Using GENEHUNTER-MODSCORE with an Application to Familial Pancreatic Cancer
Published in Human heredity (01-01-2024)“…Joint linkage and association (JLA) analysis combines two disease gene mapping strategies: linkage information contained in families and association…”
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Incidental findings in pancreas screening programs for high-risk individuals: Results from three European expert centers
Published in United European gastroenterology journal (01-06-2019)“…Background Widespread abdominal imaging has led to a substantial increase in the detection of incidentalomas. Currently, an increasing number of centers offer…”
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The German National Case Collection for Familial Pancreatic Cancer (FaPaCa): Knowledge Gained in 20 Years
Published in Deutsches Ärzteblatt international (12-03-2021)Get full text
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Characteristics of familial pancreatic cancer families with additional colorectal carcinoma
Published in Familial cancer (01-07-2023)“…Familial pancreatic cancer (FPC) is a rare hereditary tumor entity with broad phenotypic heterogeneity, including colorectal carcinoma (CRC) in some families…”
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Pancreatic cancer screening is effective in individuals at risk with predisposing germline gene variants, but not in gene variant-negative familial pancreatic cancer families
Published in United European gastroenterology journal (19-07-2024)“…To evaluate the diagnostic yield of pancreatic cancer screening in individuals at risk (IAR) from familial pancreatic cancer (FPC) families with respect to the…”
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The German National Case Collection for Familial Pancreatic Carcinoma (FaPaCa)—Knowledge Gained in 20 Years
Published in Deutsches Ärzteblatt international (12-03-2021)“…Familial pancreatic carcinoma (FPC) is a rare hereditary tumor syndrome with a heterogeneous clinical phenotype. The study of FPC also contributes to a better…”
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Prevalence of BRCA2 and CDKN2a mutations in German familial pancreatic cancer families
Published in Familial cancer (01-09-2010)“…Previous small scale studies reported that deleterious BRCA2 and CDKN2a germline mutations contribute to a subset of families with inherited pancreatic cancer…”
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The German National Case Collection for Familial Pancreatic Cancer (FaPaCa)
Published in Deutsches Ärzteblatt international (12-03-2021)Get full text
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LCN2 and TIMP1 as Potential Serum Markers for the Early Detection of Familial Pancreatic Cancer1
Published in Translational oncology (01-04-2013)“…High-risk individuals of familial pancreatic cancer (FPC) families are considered to be good candidates for screening programs to detect early PC or its…”
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